Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Lynn Robbins"'
Autor:
Debora L. Gisch, Michelle Brennan, Blue B. Lake, Jeannine Basta, Mark S. Keller, Ricardo Melo Ferreira, Shreeram Akilesh, Reetika Ghag, Charles Lu, Ying-Hua Cheng, Kimberly S. Collins, Samir V. Parikh, Brad H. Rovin, Lynn Robbins, Lisa Stout, Kimberly Y. Conklin, Dinh Diep, Bo Zhang, Amanda Knoten, Daria Barwinska, Mahla Asghari, Angela R. Sabo, Michael J. Ferkowicz, Timothy A. Sutton, Katherine J. Kelly, Ian H. De Boer, Sylvia E. Rosas, Krzysztof Kiryluk, Jeffrey B. Hodgin, Fadhl Alakwaa, Seth Winfree, Nichole Jefferson, Aydın Türkmen, Joseph P. Gaut, Nils Gehlenborg, Carrie L. Phillips, Tarek M. El-Achkar, Pierre C. Dagher, Takashi Hato, Kun Zhang, Jonathan Himmelfarb, Matthias Kretzler, Shamim Mollah, the Kidney Precision Medicine Project (KPMP), Sanjay Jain, Michael Rauchman, Michael T. Eadon
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract There is a need to define regions of gene activation or repression that control human kidney cells in states of health, injury, and repair to understand the molecular pathogenesis of kidney disease and design therapeutic strategies. Comprehe
Externí odkaz:
https://doaj.org/article/8d81e0f3c4d54dd6b9a6681fc0df894c
Autor:
Chunling Ma, Fang Wang, Bing Han, Xiaoli Zhong, Fusheng Si, Jian Ye, Eddy C. Hsueh, Lynn Robbins, Susan M. Kiefer, Yanping Zhang, Pamela Hunborg, Mark A. Varvares, Michael Rauchman, Guangyong Peng
Publikováno v:
Molecular Cancer, Vol 21, Iss 1, Pp 1-2 (2022)
Externí odkaz:
https://doaj.org/article/2276d13ee0fa4b939f1d4f3d63820ecb
Autor:
Jeannine Basta, Lynn Robbins, Lisa Stout, Michael J. Prinsen, David W. Griggs, Michael Rauchman
Publikováno v:
Physiological Reports, Vol 8, Iss 7, Pp n/a-n/a (2020)
Abstract Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine–glycine–aspartic acid (RGD)‐binding integrins are important mediators of the pro‐fibrotic response by activating latent TGF‐β
Externí odkaz:
https://doaj.org/article/d341b803727d47eb838a4fef44f6b15e
Autor:
Katherine A. Burns, MD., Lynn Robbins, PA-C., Angela R. LeMarr, RN., BSN., ONC., Amber L. Childress, BS., RN., ONC., Diane J. Morton, MS., Melissa L. Wilson, MPH., PhD.
Publikováno v:
Arthroscopy, Sports Medicine, and Rehabilitation, Vol 1, Iss 2, Pp e123-e130 (2019)
Purpose: To determine the cost-effectiveness of knotted (KT) versus knotless (KL) methods for rotator cuff surgical repair and to assess differences in patients’ outcomes. Methods: We retrospectively identified all patients who underwent arthroscop
Externí odkaz:
https://doaj.org/article/fa40f014a60946b7a32648aec486de2b
Autor:
Chunling Ma, Fang Wang, Bing Han, Xiaoli Zhong, Fusheng Si, Jian Ye, Eddy C. Hsueh, Lynn Robbins, Susan M. Kiefer, Yanping Zhang, Pamela Hunborg, Mark A. Varvares, Michael Rauchman, Guangyong Peng
Publikováno v:
Molecular Cancer, Vol 17, Iss 1, Pp 1-21 (2018)
Abstract Background SALL1 is a multi-zinc finger transcription factor that regulates organogenesis and stem cell development, but the role of SALL1 in tumor biology and tumorigenesis remains largely unknown. Methods We analyzed SALL1 expression level
Externí odkaz:
https://doaj.org/article/c806a99500d34e7aa4ee46b94f160569
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e43098 (2012)
During kidney development, canonical Wnt signaling activates differentiation, while the transcription factor Six2 maintains the progenitor pool. These opposing signals help to regulate nephron formation and ensure the full complement of nephrons are
Externí odkaz:
https://doaj.org/article/c09a8c1e0dfa4a928491b1b204dcecbb
Autor:
Lynn Robbins
Histone post-translational modifications are key epigenetic features that define gene regulatory elements in the genome. Identifying changes in the epigenome has the potential to uncover novel disease signatures. Chromatin immunoprecipitation with se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da97a6decc1c3a031e37c4a86ee9faff
https://doi.org/10.17504/protocols.io.bp2l615o1vqe/v1
https://doi.org/10.17504/protocols.io.bp2l615o1vqe/v1
Publikováno v:
Dev Biol
Chromatin-remodeling complexes play critical roles in establishing gene expression patterns in response to developmental signals. How these epigenetic regulators determine the fate of progenitor cells during development of specific organs is not well
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f10ca9092064a0905aaeb66caa4e097
https://doi.org/10.1016/j.ydbio.2020.05.008
https://doi.org/10.1016/j.ydbio.2020.05.008
Autor:
Lynn Robbins, Michael Rauchman, Michael J. Prinsen, Jeannine Basta, David W. Griggs, Lisa Stout
Publikováno v:
Physiological Reports
Physiological Reports, Vol 8, Iss 7, Pp n/a-n/a (2020)
Physiological Reports, Vol 8, Iss 7, Pp n/a-n/a (2020)
Fibrosis is a final common pathway for many causes of progressive chronic kidney disease (CKD). Arginine–glycine–aspartic acid (RGD)‐binding integrins are important mediators of the pro‐fibrotic response by activating latent TGF‐β at sites
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1380fa2e897826743c41a16cd7101c40
https://doi.org/10.14814/phy2.14329
https://doi.org/10.14814/phy2.14329
Autor:
M. Todd Valerius, Amrita Das, Thomas L. Carroll, Michael Rauchman, Alicia R. Fessler, Leif Oxburgh, Andrew P. McMahon, Aaron C. Brown, Lynn Robbins, Jeannine Basta, Harini Ramalingam
Publikováno v:
Developmental Biology. 440:13-21
Formation of a functional kidney depends on the balance between renewal and differentiation of nephron progenitors. Failure to sustain this balance can lead to kidney failure or stem cell tumors. For nearly 60 years, we have known that signals from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9373ae4589058ccafafb1cd48930c09
https://doi.org/10.1016/j.ydbio.2018.04.020
https://doi.org/10.1016/j.ydbio.2018.04.020