Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Lynn Raymond"'
Autor:
Anne Rosser, Roger Alistair Barker, Thomas Warner, Lynn Raymond, Judith Bek, Jane Paulsen, Jeffrey Long, Janet Karen Williams, Vincent Magnotta
Publikováno v:
European Journal of Human Genetics
Clinical trials to improve day-to-day function in Huntington disease (HD) require accurate outcome measures. The DSM-5 recommends the World Health Organization Disability Assessment Schedule (WHODAS) 2.0 for use in neuropsychiatric disorders. The DSM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b5ef36f35ea895947821807c6389424
http://europepmc.org/articles/PMC4350592
http://europepmc.org/articles/PMC4350592
Autor:
Haller, Gary J., Lynn, Raymond J.
Publikováno v:
The Journal of Infectious Diseases, 1968 Apr 01. 118(2), 160-164.
Externí odkaz:
https://www.jstor.org/stable/30102478
Autor:
Eric Epping, Anne Rosser, Nellie Georgiou-Karistianis, Roger Alistair Barker, Stacie Vik, Mirza Faisal Beg, Blair Leavitt, Katherine Koenig, Julie Stout, David Moser, Lynn Raymond, Anita Goh, Phyllis Chua, Hans Johnson, Thomas Wassink, Nicole Mans, WR Wayne Martin, Carissa Gehl, Michael Hayden, Georg Bernhard Landwehrmeyer, Jane Paulsen, Jeffrey Long, Vincent Magnotta, Jess Fiedorowicz
Publikováno v:
Neurobiology of Disease, Vol 46, Iss 3, Pp 625-634 (2012)
Leukocyte 8-hydroxydeoxyguanosine (8OHdG) is an indicator of oxidative stress, impaired metabolism, and mitochondrial dysfunction, features that have been implicated in Huntington disease (HD). Increased levels of 8OHdG have been reported in the caud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c0316a37b101659a79187ff26d59cdd
http://www.sciencedirect.com/science/article/pii/S0969996112000678
http://www.sciencedirect.com/science/article/pii/S0969996112000678
Autor:
Eric Epping, Anne Rosser, Nellie Georgiou-Karistianis, Roger Alistair Barker, Stacie Vik, Mirza Faisal Beg, Katherine Koenig, Julie Stout, Deborah Harrington, David Moser, Lynn Raymond, Judith Bek, Anita Goh, Phyllis Chua, Hans Johnson, Thomas Wassink, WR Wayne Martin, Carissa Gehl, Michael Hayden, Georg Bernhard Landwehrmeyer, Jane Paulsen, Jeffrey Long, Samantha Loi, Janet Karen Williams, Vincent Magnotta, Jess Fiedorowicz
Publikováno v:
Journal of Neurology, Neurosurgery & Psychiatry. 83:612-619
BACKGROUND: Prodromal Huntington's disease (prHD) is associated with a myriad of cognitive changes but the domains that best predict time to clinical diagnosis have not been studied. This is a notable gap because some domains may be more sensitive to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a135f5732535f76320f512b8d9237324
https://doi.org/10.1136/jnnp-2011-301732
https://doi.org/10.1136/jnnp-2011-301732
Autor:
Anne-Catherine Bachoud-Lévi, Lynn Raymond, Jerome De Seze, Carissa Gehl, Francis Walker, Kathleen Shannon, Jane Paulsen
Publikováno v:
Psychiatry Research. 188:372-376
Huntington disease (HD) is a neurodegenerative condition characterized by cognitive impairments, motor abnormalities, and psychiatric disturbance. An increased risk for suicide has been documented. The majority of HD research has focused on cognitive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84ce098dd158cc3d5ae89838081f517d
https://doi.org/10.1016/j.psychres.2011.05.006
https://doi.org/10.1016/j.psychres.2011.05.006
Autor:
Peggy Nopoulos, Anne Rosser, Stefan Klöppel, Roger Alistair Barker, Stacie Vik, Douglas Langbehn, Thomas Warner, Lynn Raymond, Hans Johnson, Georg Bernhard Landwehrmeyer, Jane Paulsen, Vincent Magnotta
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 3, Pp 544-554 (2010)
Neuroimaging studies of subjects who are gene-expanded for Huntington Disease, but not yet diagnosed (termed prodromal HD), report that the cortex is "spared," despite the decrement in striatal and cerebral white-matter volume. Measurement of whole-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b61cb4a0ebc3bb364c8b17d40e3aec8c
http://www.sciencedirect.com/science/article/pii/S096999611000238X
http://www.sciencedirect.com/science/article/pii/S096999611000238X
Autor:
Eric Epping, Peggy Nopoulos, Anne Rosser, Nellie Georgiou-Karistianis, Stefan Klöppel, Roger Alistair Barker, Stacie Vik, Yongxia (Sharon) Zhou, Mirza Faisal Beg, Douglas Langbehn, Thomas Warner, Julie Stout, David Moser, Lynn Raymond, Ergun Uc, Anita Goh, Phyllis Chua, Hans Johnson, Kylie Radford, Thomas Wassink, Alexandra Margaret Ure, Charlotte Soneson, William Coryell, Carmela Pestell, WR Wayne Martin, Michael Hayden, Georg Bernhard Landwehrmeyer, Jane Paulsen, Vincent Magnotta
Publikováno v:
Neurobiology of Disease, Vol 40, Iss 3, Pp 531-543 (2010)
Huntington disease (HD) is a fatal neurodegenerative disorder caused by an expanded CAG repeat. Its length can be used to estimate the time of clinical diagnosis, which is defined by overt motor symptoms. Non-motor symptoms begin before motor onset,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b9b1556aa6f8f6b0bcd5f97f8c6b9ef
https://doi.org/10.1016/j.nbd.2010.07.013
https://doi.org/10.1016/j.nbd.2010.07.013
Autor:
Peggy Nopoulos, Anne Rosser, Nellie Georgiou-Karistianis, Stefan Klöppel, Roger Alistair Barker, Stacie Vik, Douglas Langbehn, Thomas Warner, Julie Stout, David Moser, Lynn Raymond, Ergun Uc, Anita Goh, Phyllis Chua, Hans Johnson, Kylie Radford, Alexandra Margaret Ure, William Coryell, WR Wayne Martin, Michael Hayden, Georg Bernhard Landwehrmeyer, Jane Paulsen, J. Timothy Greenamyre, Janet Karen Williams, Vincent Magnotta
Publikováno v:
Movement Disorders. 25:2595-2603
The basic aim of this study was to evaluate the current accepted standard clinical endpoint for the earliest-studied HD participants likely to be recruited into clinical trials. As the advent of genetic testing for HD, it is possible to identify gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::62311fd27fe1af2d0f90d054172de7c1
https://doi.org/10.1002/mds.23337
https://doi.org/10.1002/mds.23337
Autor:
Anne-Catherine Bachoud-Lévi, Kelly Ormond, Lynn Raymond, Carissa Gehl, Francis Walker, Jane Paulsen
Publikováno v:
Journal of Nervous & Mental Disease. 198:334-338
Although current reports document a high rate of obsessive and compulsive symptoms (O/Cs) in Huntington's disease (HD), there have been no studies published that have made an attempt to identify comorbidities of O/Cs in HD. We examined O/Cs in 1642 i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45fcd7e18399f7fca11609eb5cb91184
https://doi.org/10.1097/nmd.0b013e3181da852a
https://doi.org/10.1097/nmd.0b013e3181da852a
Autor:
Anne Rosser, Stefan Klöppel, Roger Alistair Barker, Stacie Vik, Douglas Langbehn, Thomas Warner, Julie Stout, Lynn Raymond, Hans Johnson, Michael Hayden, Georg Bernhard Landwehrmeyer, Jane Paulsen, Vincent Magnotta
Publikováno v:
Movement Disorders. 24:1763-1772
The PREDICT-HD study seeks to identify clinical and biological markers of Huntington's disease in premanifest individuals who have undergone predictive genetic testing. We compared baseline motor data between gene-expansion carriers (cases) and nonge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36ab0aa8c1196ce4cbf4e1778f374bfd
https://doi.org/10.1002/mds.22601
https://doi.org/10.1002/mds.22601