Zobrazeno 1 - 10
of 1 042
pro vyhledávání: '"Lynn N"'
Autor:
Davide Monteferrario, Marion David, Satish K. Tadi, Yuanyue Zhou, Irène Marchetti, Caroline Jeanneau, Gaëlle Saviane, Coralie F. Dupont, Angélique E. Martelli, Lynn N. Truong, Jason A. Eshleman, Colman C. Ng, Marshall W. Huston, Gregory D. Davis, Jason D. Fontenot, Andreas Reik, Maurus de la Rosa, David Fenard
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 32, Iss 2, Pp 101255- (2024)
Gene silencing without gene editing holds great potential for the development of safe therapeutic applications. Here, we describe a novel strategy to concomitantly repress multiple genes using zinc finger proteins fused to Krüppel-Associated Box rep
Externí odkaz:
https://doaj.org/article/269b2cd01d1848aea9b701b0a3bea73b
Publikováno v:
Pharmaceutics, Vol 15, Iss 11, p 2624 (2023)
The purpose of this literature review is to comprehensively summarize changes in the expression of phase II drug-metabolizing enzymes and drug transporters in both the pregnant woman and the placenta. Using PubMed®, a systematic search was conducted
Externí odkaz:
https://doaj.org/article/a96c35c23eea4e178c7fec153ecf8106
Publikováno v:
Journal of Glaciology, Vol 68, Pp 417-430 (2022)
This paper presents a physics-based macroscale model for the densification of dry snow which provides for a smooth transition between densification by grain-boundary sliding (stage 1) and densification by power-law creep (stage 2). The model uses est
Externí odkaz:
https://doaj.org/article/dbee26ba302242f6b1a9248d1f2cc23a
Publikováno v:
Ecosphere, Vol 14, Iss 2, Pp n/a-n/a (2023)
Abstract Ranges of species around the world are expected to contract in response to climate change. Species distribution models (SDMs) are a powerful tool for predicting changes in habitat availability, but the variables selected to create SDMs influ
Externí odkaz:
https://doaj.org/article/adc2452da9704143b2db7b97c2149497
Autor:
Lynn N Jena, Lindsey A Bennie, Emma M McErlean, Sreekanth Pentlavalli, Kim Glass, James F Burrows, Vicky L Kett, Niamh E Buckley, Jonathan A Coulter, Nicholas J Dunne, Helen O McCarthy
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-18 (2021)
Abstract Glioblastoma multiforme (GBM) is an incurable aggressive brain cancer in which current treatment strategies have demonstrated limited survival benefit. In recent years, nitrogen-containing bisphosphonates (N-BPs) have demonstrated direct ant
Externí odkaz:
https://doaj.org/article/ff00e18b61e540388dddf96e6bc47180
Autor:
Thangavelautham Suhitharan, Christopher Weiyang Liu, Lynn N Chen, Amalina Anwar, Boyu Lu Zhao, Clin K Y Lai, Wei Heng Ng, Vui Kian Ho, Jean C J Liu
Publikováno v:
BMJ Open, Vol 11, Iss 11 (2021)
Objectives Intensive care audits point to family refusal as a major barrier to organ donation. In this study, we sought to understand refusal by accounting for the decision-maker’s mindset. This focused on: (1) how decisions compare when made on be
Externí odkaz:
https://doaj.org/article/40e2e6c8c2db44e7b2481d33a21cc31a
Autor:
Zach Aralis, Stewart Comer, Henning Ansorg, Carl Palmer, Jennifer Smith, Stuart C. Feinstein, Lynn N. Fitzgibbons, Carolina Arias
Publikováno v:
Diagnostics, Vol 12, Iss 11, p 2805 (2022)
The emergence of the SARS-CoV-2 Omicron variant in 2021 is associated with a global surge of cases in late 2021 and early 2022. Identifying the introduction of novel SARS-CoV-2 variants to a population is imperative to inform decisions by clinicians
Externí odkaz:
https://doaj.org/article/14238a0d9def455d841f253ac50b5900
Autor:
David E. Paschon, Stephanie Lussier, Tenzin Wangzor, Danny F. Xia, Patrick W. Li, Sarah J. Hinkley, Nicholas A. Scarlott, Stephen C. Lam, Adam J. Waite, Lynn N. Truong, Nimisha Gandhi, Bhakti N. Kadam, Deepak P. Patil, David A. Shivak, Gary K. Lee, Michael C. Holmes, Lei Zhang, Jeffrey C. Miller, Edward J. Rebar
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Genome editing often requires cleavage within a narrow sequence window. Here the authors develop an expanded set of zinc finger nuclease architectures that increase the available configurations by a factor of 64 and can target almost every base at lo
Externí odkaz:
https://doaj.org/article/52399a6682884a7196ea64923e436811
Autor:
Breeanne K. Jackson, Sarah L. Stock, Leila S. Harris, Joseph M. Szewczak, Lynn N. Schofield, Michelle A. Desrosiers
Publikováno v:
Ecosphere, Vol 11, Iss 6, Pp n/a-n/a (2020)
Abstract River regulation can modify natural flow regimes with deleterious effects on aquatic communities. While the effects of flow manipulation on the physical environment and populations and assemblages of aquatic organisms have been described tho
Externí odkaz:
https://doaj.org/article/7b3cfbce8b8c43768aab1c531240c5af
Autor:
Lucien Barnes, Douglas M. Heithoff, Scott P. Mahan, Gary N. Fox, Andrea Zambrano, Jane Choe, Lynn N. Fitzgibbons, Jamey D. Marth, Jeffrey C. Fried, H. Tom Soh, Michael J. Mahan
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 73-82 (2018)
Background: There is an urgent need for rapid, sensitive, and affordable diagnostics for microbial infections at the point-of-care. Although a number of innovative systems have been reported that transform mobile phones into potential diagnostic tool
Externí odkaz:
https://doaj.org/article/dc03a096f3b54706969e9747b2141ada