Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Lynn Miao"'
Autor:
Jiangling Peng, Wei Tang, Jeffrey Rawson, Lynn Miao, Nelson Gonzalez, Runkai Yin, Jiaqi Chen, Melinda Ji, Zhixuan Li, Anna Gao, Andy Z. Wu, John E. Shively, Fouad Kandeel, Junfeng Li
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1480 (2023)
Recently, a G-protein coupled receptor 44 (GPR44) was discovered to play a significant role in the process of inflammation-related diseases, including cancer and diabetes. However, the precise role of GPR44 has yet to be fully elucidated. Currently,
Externí odkaz:
https://doaj.org/article/9651c4ece46445dc974b3f96b53e9d6d
Autor:
Hongfei Ge, Jonitha Gardner, Xiaosu Wu, Ingrid Rulifson, Jinghong Wang, Yumei Xiong, Jingjing Ye, Edward Belouski, Ping Cao, Jie Tang, Ki Jeong Lee, Suzanne Coberly, Xinle Wu, Jamila Gupte, Lynn Miao, Li Yang, Natalie Nguyen, Bei Shan, Wen-Chen Yeh, Murielle M Véniant, Yang Li, Helene Baribault
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0126924 (2015)
Trefoil factor 3 (TFF3), also called intestinal trefoil factor or Itf, is a 59 amino acid peptide found as a homodimer predominantly along the gastrointestinal tract and in serum. TFF3 expression is elevated during gastrointestinal adenoma progressio
Externí odkaz:
https://doaj.org/article/80d053555e6a4ed7aa6585d3c09320bb
Autor:
Jian Luo, Gayathri Swaminath, Sean P Brown, Jane Zhang, Qi Guo, Michael Chen, Kathy Nguyen, Thanhvien Tran, Lynn Miao, Paul J Dransfield, Marc Vimolratana, Jonathan B Houze, Simon Wong, Maria Toteva, Bei Shan, Frank Li, Run Zhuang, Daniel C-H Lin
Publikováno v:
PLoS ONE, Vol 7, Iss 10, p e46300 (2012)
Type 2 diabetes is characterized by impaired glucose homeostasis due to defects in insulin secretion, insulin resistance and the incretin response. GPR40 (FFAR1 or FFA1) is a G-protein-coupled receptor (GPCR), primarily expressed in insulin-producing
Externí odkaz:
https://doaj.org/article/0849b9dfe7b244fab2862894d2869154
Autor:
Lynn Miao, Junfeng Li, Fouad Kandeel, Junie Chea, Erasmus Poku, Wei Tang, John E. Shively, Jeffrey Rawson, Feng Sui, Lin Li
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-8 (2019)
[68Ga]DO3A-VS-Cys40-Exendin-4, a glucagon-like peptide 1 receptor agonist, was evaluated as a potential PET tracer for the quantitation of human islets transplanted to the liver. The short-lived PET radionuclide 68Ga, available on a regular basis fro
Autor:
Frank Li, Xianyun Jiao, Qi Guo, Julio C. Medina, Sean P. Brown, Jian Luo, Daniel C.-H. Lin, Jonathan B. Houze, Lynn Miao, Yingcai Wang, Liusheng Zhu, Tiffany L. Correll, Michael D. Bartberger, Jane Zhang, Run Zhuang, Jiwen Jim Liu, Yongli Su, David Chow, Gayathri Swaminath, An-Rong Li, Paul John Dransfield, Khanh Nguyen, Zhongyu Wang, Simon Wong, Marc Vimolratana, Xiaohui Du, Ming Yu, Thanhvien Tran, Vatee Pattaropong, Annie Kasparian
GPR40 (FFAR1 or FFA1) is a target of high interest being pursued to treat type II diabetes due to its unique mechanism leading to little risk of hypoglycemia. We recently reported the discovery of AM-1638 (2), a potent full agonist of GPR40. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57cc725905f00876cc74627d7371cf38
https://europepmc.org/articles/PMC4027505/
https://europepmc.org/articles/PMC4027505/
Autor:
Jenny Ying-Lin Lu, Lily Liu, Helene Baribault, Heather Salomonis, Qiong Cao, Jonathan B. Houze, Franziska Steger, Yumei Xiong, Jane Zhang, Daniel C.-H. Lin, Lynn Miao, Suzanne Coberly, Gayathri Swaminath, Yingcai Wang, Li Yang, Qi Guo, Margrit Schwarz, Simon Wong, Paul John Dransfield, Jiwen Jim Liu, Ralf Schwandner
Publikováno v:
Molecular and cellular endocrinology. 369(1-2)
FFA1 (GPR40) and GPR120 are G-protein-coupled receptors activated by long-chain fatty acids. FFA1 is expressed in pancreatic β-cells, where it regulates glucose-dependent insulin secretion, and GPR120 has been implicated in mediating GLP-1 secretion
Autor:
Gayathri Swaminath, Kathy Nguyen, Sean P. Brown, Simon Wong, Marc Vimolratana, Michael Chen, Run Zhuang, Paul John Dransfield, Jane Zhang, Maria M. Toteva, Daniel C.-H. Lin, Thanhvien Tran, Jian Luo, Bei Shan, Frank Li, Lynn Miao, Jonathan B. Houze, Qi Guo
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 10, p e46300 (2012)
PLoS ONE, Vol 7, Iss 10, p e46300 (2012)
Type 2 diabetes is characterized by impaired glucose homeostasis due to defects in insulin secretion, insulin resistance and the incretin response. GPR40 (FFAR1 or FFA1) is a G-protein-coupled receptor (GPCR), primarily expressed in insulin-producing
Autor:
Helene Baribault, Natalie Nguyen, Xinle Wu, Yang Li, Suzanne Coberly, Yumei Xiong, Lynn Miao, Ki Jeong Lee, Wen-Chen Yeh, Bei Shan, Xiaosu Wu, Edward John Belouski, Jinghong Wang, Ping Cao, Murielle M. Véniant, Ingrid C. Rulifson, Jamila Gupte, Jonitha Gardner, Jingjing Ye, Hongfei Ge, Li Yang, Jie Tang
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0126924 (2015)
PLoS ONE
PLoS ONE
Trefoil factor 3 (TFF3), also called intestinal trefoil factor or Itf, is a 59 amino acid peptide found as a homodimer predominantly along the gastrointestinal tract and in serum. TFF3 expression is elevated during gastrointestinal adenoma progressio