Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lynn Marcho"'
Publikováno v:
iScience, Vol 19, Iss , Pp 872-882 (2019)
Summary: Vascular smooth muscle cell (VSMC) proliferation promotes intimal hyperplasia (IH) in occluding vascular diseases. Here we identified a positive role of ALDH1A3 (an aldehyde dehydrogenase) in this pro-IH process. The expression of ALDH1A3, b
Externí odkaz:
https://doaj.org/article/5b152a1b77f640e9ae0dd193d80c5848
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 8 (2020)
Background Vascular smooth muscle cell phenotypic change and consequential intimal hyperplasia (IH) cause arterial stenosis and posttreatment restenosis. Smad3 is a master transcription factor, yet its underlying functional mechanisms in this disease
Externí odkaz:
https://doaj.org/article/d1868cb3d57f4377aeed9111879b6da1
Publikováno v:
J Mol Cell Cardiol
Biological aging is attributed to progressive dysfunction in systems governing genetic and metabolic integrity. At the cellular level, aging is evident by accumulated DNA damage and mutation, reactive oxygen species, alternate lipid and protein modif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28bccd4ff5dae9a194435c779a2100c9
https://doi.org/10.1016/j.yjmcc.2021.04.007
https://doi.org/10.1016/j.yjmcc.2021.04.007
Autor:
Federica Accornero, Alessandro Canella, Erin McGrail, Lynn Marcho, Bryan A. Whitson, Richard J. Gumina, Shamama Nishat, Matthew S. Stratton, Ashley Francois, Oscar Bermeo-Blanco, Paul M.L. Janssen
Publikováno v:
Circulation Research. 129
Over 6 million Americans suffer from heart failure (HF) while the 5-year mortality rate following first admission for HF is over 40%. Cardiac fibrosis is a clinical hallmark of HF, regardless of the initiating pathology and is thought to contribute t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28d448873b7ab67c21bb0c3e5acc0c2e
https://doi.org/10.1161/res.129.suppl_1.mp259
https://doi.org/10.1161/res.129.suppl_1.mp259
Publikováno v:
iScience
iScience, Vol 19, Iss, Pp 872-882 (2019)
iScience, Vol 19, Iss, Pp 872-882 (2019)
Summary Vascular smooth muscle cell (VSMC) proliferation promotes intimal hyperplasia (IH) in occluding vascular diseases. Here we identified a positive role of ALDH1A3 (an aldehyde dehydrogenase) in this pro-IH process. The expression of ALDH1A3, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3906784d31e5e69bb4b409d001b536c9
https://doi.org/10.1016/j.isci.2019.08.044
https://doi.org/10.1016/j.isci.2019.08.044
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Vascular smooth muscle cell phenotypic change and consequential intimal hyperplasia (IH) cause arterial stenosis and posttreatment restenosis. Smad3 is a master transcription factor, yet its underlying functional mechanisms in this disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::373473160f0ac08201c19bd1ebe046a5
https://pubmed.ncbi.nlm.nih.gov/32306814
https://pubmed.ncbi.nlm.nih.gov/32306814
Autor:
Yitao Huang, Lynn Marcho, Hongtao Shen, Go Urabe, Mengxue Zhang, Lian-Wang Guo, Jing Li, K. Craig Kent, Bowen Wang
A divergent member of the polo-like kinase family, PLK4 is known for its canonical role in centriole duplication. Its non-canonical function and regulators are poorly defined. Here we investigated PLK4’s activation and expression and regulations th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7914133bad2bec1ed2d7f4ece11a96
https://doi.org/10.1101/570267
https://doi.org/10.1101/570267
