Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lynn Lehmann"'
Autor:
Xiao-Fen Chen, Lynn Lehmann, Justin J. Lin, Ajay Vashisht, Ryan Schmidt, Roberto Ferrari, Chengyang Huang, Robin McKee, Amber Mosley, Kathrin Plath, Siavash K. Kurdistani, James Wohlschlegel, Michael Carey
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1061-1067 (2012)
A key feature of RNA polymerase II (Pol II) preinitiation complexes (PICs) is their ability to coordinate transcription initiation with chromatin modification and remodeling. To understand how this coordination is achieved, we employed extensive prot
Externí odkaz:
https://doaj.org/article/ff71cc4b35ea430ca662477a2c4ce00b
Publikováno v:
Journal of Biological Chemistry. 288:35913-35924
ZMIZ2, also named ZIMP7, is a protein inhibitor of activated STAT (PIAS)-like protein and a transcriptional coactivator. In this study, we investigated the interaction between ZMIZ2 and β-catenin, a key regulator of the Wnt signaling pathway. We dem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72bd2dfaef418ae8563724fbdc1616be
https://doi.org/10.1074/jbc.m113.529727
https://doi.org/10.1074/jbc.m113.529727
Autor:
Giancarlo Bonora, Justin J. Lin, Nancy Tran, Ajay A. Vashisht, Kathrin Plath, James A. Wohlschlegel, Lynn Lehmann, Rupa Sridharan, Michael Carey
Publikováno v:
Genes & Development. 25:2198-2209
Murine Chd1 (chromodomain helicase DNA-binding protein 1), a chromodomain-containing chromatin remodeling protein, is necessary for embryonic stem (ES) cell pluripotency. Chd1 binds to nucleosomes trimethylated at histone 3 Lys 4 (H3K4me3) near the b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbdf8b896a24bff2d510f7aca5d3e60d
https://doi.org/10.1101/gad.17554711
https://doi.org/10.1101/gad.17554711
Publikováno v:
The FASEB Journal. 29
Characterization of biomolecular interactions, such as protein-protein, protein-nucleic acid or protein-small molecule, provides critical insights into cellular processes, and is essential for the development of drug diagnostics and therapeutics.Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3c887d1e5e069ecaec83dd9652f3d3
https://doi.org/10.1096/fasebj.29.1_supplement.778.4
https://doi.org/10.1096/fasebj.29.1_supplement.778.4
Publikováno v:
Molecular and Cellular Biology. 26:8857-8867
Beta-catenin plays multiple roles in cell-cell adhesion and Wnt signal transduction. Through the Wnt signal, the cellular level of beta-catenin is constitutively regulated by the multicomponent destruction complex containing glycogen synthase kinase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::124ce9f91a613eabe9c40c7c88737d99
https://doi.org/10.1128/mcb.01031-06
https://doi.org/10.1128/mcb.01031-06
Publikováno v:
Infection and Immunity. 74:399-409
Staphylococcus aureus can grow virtually anywhere in the human body but needs to import proline through low- and high-affinity proline transporters to survive. This study examined the regulation of the S. aureus putP gene, which encodes a high-affini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::405bd2c48664d033de25c742af9d2634
https://doi.org/10.1128/iai.74.1.399-409.2006
https://doi.org/10.1128/iai.74.1.399-409.2006
Autor:
Michael Prakesch, Rima Al-awar, Kenneth Lee, Lynn Lehmann, Gennadiy Poda, Danka Vuga, David Chiovitti, Colleen Schweitzer, Marella D. Canny, Julie L. Lucas, John B. Patterson, Nero Thevakumaran, Andras Toro, Nicole M. Duffy, Qingping Zeng, Igor Kurinov, Daniel Durocher, David Uehling, Victor Tam, Brian J. Wilson, Manisha Talukdar, Mario Sanches, Frank Sicheri
Publikováno v:
Nature communications
Endoplasmic reticulum (ER) stress activates the unfolded protein response and its dysfunction is linked to multiple diseases. The stress transducer IRE1α is a transmembrane kinase endoribonuclease (RNase) that cleaves mRNA substrates to re-establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a763c3a28c964003e2743b791e1302b
https://pubmed.ncbi.nlm.nih.gov/25164867
https://pubmed.ncbi.nlm.nih.gov/25164867
Autor:
Siavash K. Kurdistani, Ajay A. Vashisht, Roberto Ferrari, Lynn Lehmann, Michael Carey, James A. Wohlschlegel
Despite the important role of Polycomb in genome-wide silencing, little is known of the specific biochemical mechanism by which it inactivates transcription. Here we address how recombinant Polycomb repressive complex 1 (PRC1) inhibits activated RNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3c8bc60edbd6d5266af713c31d4b219
https://europepmc.org/articles/PMC3476247/
https://europepmc.org/articles/PMC3476247/
Autor:
Justin J. Lin, Lynn Lehmann, Michael Carey, James A. Wohlschlegel, Chengyang Huang, Roberto Ferrari, Robin McKee, Kathrin Plath, Xiao Fen Chen, Ajay A. Vashisht, Siavash K. Kurdistani, Ryan Schmidt, Amber L. Mosley
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1061-1067 (2012)
SummaryA key feature of RNA polymerase II (Pol II) preinitiation complexes (PICs) is their ability to coordinate transcription initiation with chromatin modification and remodeling. To understand how this coordination is achieved, we employed extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3e0d61b3e8f9e1707dd3f08086e6549