Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Lynn Law"'
Autor:
Hayden Brochu, Ruihan Wang, Tammy Tollison, Chul-Woo Pyo, Alexander Thomas, Elizabeth Tseng, Lynn Law, Louis J. Picker, Michael Gale, Daniel E. Geraghty, Xinxia Peng
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-13 (2022)
The alternative splicing and genetic variations across the whole MHC-E locus of Rhesus Macaques (Mamu-E) are analysed, which provides a foundation for more comprehensive research of Mamu-E and informs translational research of CMV-based vaccines.
Externí odkaz:
https://doaj.org/article/ce27b75a4ef747ec83fe39c04b0d8f01
Autor:
Fredrik Barrenäs, Scott G Hansen, Lynn Law, Connor Driscoll, Richard R Green, Elise Smith, Jean Chang, Inah Golez, Taryn Urion, Xinxia Peng, Leanne Whitmore, Daniel Newhouse, Colette M Hughes, David Morrow, Kurt T Randall, Andrea N Selseth, Julia C Ford, Roxanne M Gilbride, Bryan E Randall, Emily Ainslie, Kelli Oswald, Rebecca Shoemaker, Randy Fast, William J Bosche, Michael K Axthelm, Yoshinori Fukazawa, George N Pavlakis, Barbara K Felber, Slim Fourati, Rafick-Pierre Sekaly, Jeffrey D Lifson, Jan Komorowski, Ewelina Kosmider, Danica Shao, Wenjun Song, Paul T Edlefsen, Louis J Picker, Michael Gale
Publikováno v:
PLoS Pathogens, Vol 17, Iss 7, p e1009278 (2021)
Simian immunodeficiency virus (SIV) challenge of rhesus macaques (RMs) vaccinated with strain 68-1 Rhesus Cytomegalovirus (RhCMV) vectors expressing SIV proteins (RhCMV/SIV) results in a binary outcome: stringent control and subsequent clearance of h
Externí odkaz:
https://doaj.org/article/cd57c9263ff449bb8bd672c756c1208a
Autor:
Fredrik Barrenas, Kevin Raehtz, Cuiling Xu, Lynn Law, Richard R. Green, Guido Silvestri, Steven E. Bosinger, Andrew Nishida, Qingsheng Li, Wuxun Lu, Jianshui Zhang, Matthew J. Thomas, Jean Chang, Elise Smith, Jeffrey M. Weiss, Reem A. Dawoud, George H. Richter, Anita Trichel, Dongzhu Ma, Xinxia Peng, Jan Komorowski, Cristian Apetrei, Ivona Pandrea, Michael Gale
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-15 (2019)
Here, the authors compare gene expression signatures in rectal tissues of African green monkeys (AGMs) and rhesus macaques (RMs) acutely infected with simian immunodeficiency virus and find that AGMs rapidly activate and maintain evolutionarily conse
Externí odkaz:
https://doaj.org/article/107c63b54b1f4ef0ab68efce33b6be89
Autor:
Kevin D Raehtz, Fredrik Barrenäs, Cuiling Xu, Kathleen Busman-Sahay, Audrey Valentine, Lynn Law, Dongzhu Ma, Benjamin B Policicchio, Viskam Wijewardana, Egidio Brocca-Cofano, Anita Trichel, Michael Gale, Brandon F Keele, Jacob D Estes, Cristian Apetrei, Ivona Pandrea
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008333 (2020)
Unlike HIV infection, SIV infection is generally nonpathogenic in natural hosts, such as African green monkeys (AGMs), despite life-long high viral replication. Lack of disease progression was reportedly based on the ability of SIV-infected AGMs to p
Externí odkaz:
https://doaj.org/article/5c90518ccf3c43f8b835fdcb20bf9cea
Autor:
Giacomo Gorini, Slim Fourati, Monica Vaccari, Mohammad Arif Rahman, Shari N Gordon, Dallas R Brown, Lynn Law, Jean Chang, Richard Green, Fredrik Barrenäs, Namal P M Liyanage, Melvin N Doster, Luca Schifanella, Massimiliano Bissa, Isabela Silva de Castro, Robyn Washington-Parks, Veronica Galli, Deborah H Fuller, Sampa Santra, Michael Agy, Ranajit Pal, Robert E Palermo, Georgia D Tomaras, Xiaoying Shen, Celia C LaBranche, David C Montefiori, David J Venzon, Hung V Trinh, Mangala Rao, Michael Gale, Rafick P Sekaly, Genoveffa Franchini
Publikováno v:
PLoS Pathogens, Vol 16, Iss 3, p e1008377 (2020)
The recombinant Canarypox ALVAC-HIV/gp120/alum vaccine regimen was the first to significantly decrease the risk of HIV acquisition in humans, with equal effectiveness in both males and females. Similarly, an equivalent SIV-based ALVAC vaccine regimen
Externí odkaz:
https://doaj.org/article/8a54f872d2bf45ab819091328f14d7f3
Autor:
Evan S. Walsh, Tammy S. Tollison, Hayden N. Brochu, Brian I. Shaw, Kayleigh R. Diveley, Hsuan Chou, Lynn Law, Allan D. Kirk, Michael Gale, Xinxia Peng
Publikováno v:
J Immunol
Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired H and L chains of Igs and VDJ and VJ chains of TCRs from thousands of single cells simultaneously in humans and mice. Despite rhesus maca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::654ba84318c74cb343a7a63377945ac5
https://doi.org/10.4049/jimmunol.2100824
https://doi.org/10.4049/jimmunol.2100824
Autor:
Fredrik Barrenas, Kevin Raehtz, Cuiling Xu, Lynn Law, Richard R. Green, Guido Silvestri, Steven E. Bosinger, Andrew Nishida, Qingsheng Li, Wuxun Lu, Jianshui Zhang, Matthew J. Thomas, Jean Chang, Elise Smith, Jeffrey M. Weiss, Reem A. Dawoud, George H. Richter, Anita Trichel, Dongzhu Ma, Xinxia Peng, Jan Komorowski, Cristian Apetrei, Ivona Pandrea, Michael Gale
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-1 (2019)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/3bc35ea511634fe39ee935e861ff878b
Autor:
Daniel Malouli, Roxanne M. Gilbride, Helen L. Wu, Joseph M. Hwang, Nicholas Maier, Colette M. Hughes, Daniel Newhouse, David Morrow, Abigail B. Ventura, Lynn Law, Jennifer Tisoncik-Go, Leanne Whitmore, Elise Smith, Inah Golez, Jean Chang, Jason S. Reed, Courtney Waytashek, Whitney Weber, Husam Taher, Luke S. Uebelhoer, Jennie L. Womack, Matthew R. McArdle, Junwei Gao, Courtney R. Papen, Jeffrey D. Lifson, Benjamin J. Burwitz, Michael K. Axthelm, Jeremy Smedley, Klaus Früh, Michael Gale, Louis J. Picker, Scott G. Hansen, Jonah B. Sacha
Publikováno v:
Cell Host & Microbe. 30:1207-1218.e7
Strain 68-1 rhesus cytomegalovirus expressing simian immunodeficiency virus (SIV) antigens (RhCMV/SIV) primes MHC-E-restricted CD8+ T cells that control SIV replication in 50%-60% of the vaccinated rhesus macaques. Whether this unconventional SIV-spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbeca3c5f31b92deb05830f7216b8bf8
https://doi.org/10.1016/j.chom.2022.07.013
https://doi.org/10.1016/j.chom.2022.07.013
Autor:
Walsh Es, Brian I. Shaw, Tollison T, Lynn Law, Michael Gale, Hayden N. Brochu, Allan D. Kirk, Chou H, Xinxia Peng, Kayleigh Diveley
Recent advancements in microfluidics and high-throughput sequencing technologies have enabled recovery of paired heavy- and light-chains of immunoglobulins (Ig) and VDJ- and VJ-chains of T cell receptors (TCR) from thousands of single cells simultane
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::718ec981affa8797260928d15caa8863
https://doi.org/10.1101/2021.08.17.456682
https://doi.org/10.1101/2021.08.17.456682
