Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Lynn Hartweck"'
Autor:
Sasha Z. Prisco, Lynn Hartweck, Jennifer L. Keen, Neal Vogel, Felipe Kazmirczak, Megan Eklund, Anna R. Hemnes, Evan L. Brittain, Kurt W. Prins
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 9 (2022)
BackgroundHeightened glycolytic flux is associated with right ventricular (RV) dysfunction in pulmonary arterial hypertension (PAH). Methylglyoxal, a glycolysis byproduct, is a highly reactive dicarbonyl that has toxic effects via non-enzymatic post-
Externí odkaz:
https://doaj.org/article/daff707aaf37400eb949e6b56db66cc5
Autor:
Sasha Z. Prisco, Lauren Rose, Francois Potus, Lian Tian, Danchen Wu, Lynn Hartweck, Ruaa Al-Qazazi, Monica Neuber-Hess, Megan Eklund, Steven Hsu, Thenappan Thenappan, Stephen L. Archer, Kurt W. Prins
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 19, p 7278 (2020)
The hexosamine biosynthetic pathway (HBP) converts glucose to uridine-diphosphate-N-acetylglucosamine, which, when added to serines or threonines, modulates protein function through protein O-GlcNAcylation. Glutamine-fructose-6-phosphate amidotransfe
Externí odkaz:
https://doaj.org/article/3d3a8833186743b3b652e0c4b8189161
Publikováno v:
Journal of the American College of Cardiology. 81:4014
Autor:
Sasha Z. Prisco, Lynn Hartweck, Jennifer Keen, Felipe Kazmirczak, Megan Eklund, Ravinder R. Mallugari, Anna Ryan Hemnes, Evan Brittain, Kurt Prins
Publikováno v:
SSRN Electronic Journal.
Autor:
Sasha Z Prisco, Megan Eklund, Lynn Hartweck, Ann QUICK, Satadru K Lahiri, Xander H Wehrens, Kurt W Prins
Publikováno v:
Circulation. 144
Introduction: Junctophilin-2 (JPH2) plays a crucial role in t-tubule structure/function and gene regulation in cardiomyocytes. In addition, JPH2 downregulation causes mitochondrial dysfunction and mitofusin-2 (MFN2) dysregulation, but the link betwee