Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Lynn Haggis"'
Autor:
Richard J. Looby, Thomas J. McMurry, Manija A. Kazmi, Kenneth E. Carlson, Lynn Haggis, Jay M. Janz, Adam O'Shea, Stephen W. Hunt, Ed McBride, Pallavi Sachdev, Yong Ren, Boris Tchernychev, Thomas P. Sakmar, Qing Deng
Publikováno v:
Proceedings of the National Academy of Sciences. 107:22255-22259
The G protein-coupled receptor (GPCR), chemokine CXC-type receptor 4 (CXCR4), and its ligand, CXCL12, mediate the retention of polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs) in the bone marrow. Agents that di
Autor:
Daniel J.-F. Chinnapen, Stephen W. Hunt, Manija A. Kazmi, Richard J. Looby, Yong Ren, Kenneth E. Carlson, Thomas P. Sakmar, Amy Ying Lin, Tom W. Muir, Lynn Haggis, Jay M. Janz, Christoph Seibert, Thomas J. McMurry, Amy Grunbeck, Pallavi Sachdev
Publikováno v:
Journal of the American Chemical Society. 133(40)
Cell surface heptahelical G protein-coupled receptors (GPCRs) mediate critical cellular signaling pathways and are important pharmaceutical drug targets. (1) In addition to traditional small-molecule approaches, lipopeptide-based GPCR-derived pepduci