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pro vyhledávání: '"Lynn Enders Stephens"'
Autor:
J. Scott Pounds, Un Hoi Do, Janet L. Gross, Lynn Enders Stephens, Lisa Johnson Buenaga, William F. Herblin
Publikováno v:
Biochemical pharmacology. 40(2)
The microbial alkaloid staurosporine is a member of a recently described family of protein kinase inhibitors. [N,N-dimethyl-3H]N-dimethylstaurosporine ([3H]DMS) was prepared from staurosporine by methylation with [3H]methyl iodide. Since staurosporin
Publikováno v:
Journal of cellular physiology. 141(2)
The activation of protein kinase C (PKC) by diacylglycerol or tumor promoters plays a pivotal role in signal transduction and subsequent activation of cellular processes. Since the activity of this enzyme is dependent on its immediate lipid domain, i