Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Lynn C. Yeoman"'
Autor:
Eric Sheinin, Roger L. Williams, Lynn C. Yeoman, Lokesh Bhattycharyya, Roger Dabbah, Walter W. Hauck
Publikováno v:
The AAPS Journal. 7:E786-E812
This article examines the United States Pharmacopeia (USP) and its role in assessing the equivalence and inequivalence of biological and biotechnological drug substances and products-a role USP has played since its founding in 1820. A public monograp
Autor:
Lynn C. Yeoman, Mark A. Zorbas
Publikováno v:
Experimental Cell Research. 206:49-57
Transforming growth factor-alpha (TGF alpha) is able to elicit growth in many target cells expressing a functional epidermal growth factor (EGF) receptor. Other laboratories have reported that the TGF alpha precursor polypeptide (proTGF alpha) is ine
Autor:
Lynn C. Yeoman, Bonnie A. New
Publikováno v:
Journal of Cellular Physiology. 150:320-326
Basic fibroblast growth factor (bFGF) has been shown to be mitogenic to many different eukaryotic cell lines of mesodermal and neuroectodermal origin. Addition of exogenous bFGF to the chemically defined media of five characterized human colon tumor
Publikováno v:
Antisense Research and Development. 2:51-59
A natural DNA oligomer (15-mer) was synthesized with a sequence complementary to the translation initiation codon region of the human TGF-alpha mRNA and mixed with Lipofectin to form unilamellar complexes. It was found that tumor cell growth was inhi
Publikováno v:
Medical Education Online; Vol 3 (1998)
Purpose: To examine the profile of medical students’ resource use in a longitudinal problem-based learning course and to examine patterns of change. Method: Over a six-month period, 116 students indicated on resource checklists which resources they
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 73(5)
Autor:
M. A. Zorbas, Tatsuro Irimura, A. M. McIsaac, Lynn C. Yeoman, Bruce M. Boman, C. L. Novotny‐Smith, Gary E. Gallick
Publikováno v:
Journal of cellular physiology. 157(2)
Although the biologic response modifier tumor necrosis factor-alpha (TNF) is a known differentiation inducer in hematopoietic cells, its role in differentiation of other tissue types has yet to be elucidated. In the studies presented here, TNF treatm
Autor:
Charles W. Taylor, Lynn C. Yeoman
Publikováno v:
Anti-cancer drugs. 3(5)
Recent interest in site-selective cAMP analogs has focused on the role of 8-chloro-adenosine (8-Cl-adenosine) in the inhibition of tumor cell growth by 8-chloro-cAMP (8-Cl-cAMP) (Van Lookeren Campagne, et al. Cancer Res 1991; 51: 1600-5). We have eva
Publikováno v:
Cancer letters. 62(2)
Six human colon tumor cell lines were analyzed for their constitutive levels of the c-myc protein. The nuclear proto-oncogene, c-myc, was detected as an expressed product in all of the human colon tumor cell lines analyzed. The poorly differentiated
Autor:
Richard G. Cook, Lynn C. Yeoman, Harris Busch, R. Reddy, Robert L. Ochs, Eng M. Tan, Michael A. Lischwe, M Reichlin
Publikováno v:
Journal of Biological Chemistry. 260:14304-14310
A new scleroderma antigen of Mr = 34,000; pI, 8.5 has been identified. This 34-kDa protein is a nucleolar protein as determined by immunostaining procedures with affinity-purified antibodies. The 34-kDa protein was shown to localize to the fibrillar