Zobrazeno 1 - 10 of 17 pro vyhledávání: '"Lynn Berndt-Weis"'
1
Global transcriptional characterization of a mouse pulmonary epithelial cell line for use in genetic toxicology
Autor: Andrew Williams, Lisa Marie Kauri, Carole L. Yauk, George R. Douglas, Paul D. White, M. Lynn Berndt-Weis
Publikováno v: Toxicology in Vitro. 23:816-833
Prior to its application for in vitro toxicological assays, thorough characterization of a cell line is essential. The present study uses global transcriptional profiling to characterize a lung epithelial cell line (FE1) derived from MutaMouse [White
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4948b7743edec12a43a6f5364df55f5
https://doi.org/10.1016/j.tiv.2009.04.008
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2
Toxicogenomic Analysis of Mainstream Tobacco Smoke-Exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart
Autor: Sabina Halappanavar, Andrew Williams, Martin R. Stämpfli, Carole L. Yauk, Lynn Berndt-Weis, George R. Douglas
Publikováno v: Inhalation Toxicology
Tobacco smoking is associated with cardiovascular pathology. However, the molecular mechanisms of tobacco smoke exposure that lead to initiation or exacerbation of cardiovascular disease are unclear. In this study, the effects of mainstream tobacco s
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85c9a9f53079e23b6c0ac535fb0bbf4c
http://europepmc.org/articles/PMC2607137
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3
Sidestream tobacco smoke is a male germ cell mutagen
Autor: Andrea Rowan-Carroll, Carole L. Yauk, M. Lynn Berndt-Weis, Aris Polyzos, Francesco Marchetti, Andrew M. Williams
Publikováno v: Proceedings of the National Academy of Sciences of the United States of America. 108(31)
Active cigarette smoking increases oxidative damage, DNA adducts, DNA strand breaks, chromosomal aberrations, and heritable mutations in sperm. However, little is known regarding the effects of second-hand smoke on the male germ line. We show here th
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99aaa5123cee315e9b8b84baef94f171
https://pubmed.ncbi.nlm.nih.gov/21768363
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4
Akademický článek
Systematic review and quality ranking of studies of two phthalate metabolites and anogenital distance, bone health, inflammation, and oxidative stress.
Autor: Sweeney, Marina R.1 (AUTHOR), O'Leary, Keri G.1 (AUTHOR), Jeney, Zsuzsanna1 (AUTHOR), Braunlin, Megan C.1 (AUTHOR), Gibb, Herman J.1 (AUTHOR) Herman.Gibb@gibbepi.com
Publikováno v: Critical Reviews in Toxicology. Apr2019, Vol. 49 Issue 4, p281-301. 21p. 1 Diagram, 2 Charts.
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5
Akademický článek
Comparison of toxicogenomics and traditional approaches to inform mode of action and points of departure in human health risk assessment of benzo[ a]pyrene in drinking water.
Autor: Moffat, Ivy1,2 (AUTHOR) ivy.moffat@hc-sc.gc.ca, Chepelev, Nikolai L.2 (AUTHOR) ivy.moffat@hc-sc.gc.ca, Labib, Sarah2 (AUTHOR), Bourdon-Lacombe, Julie1,2 (AUTHOR), Kuo, Byron2 (AUTHOR), Buick, Julie K.2 (AUTHOR), Lemieux, France1 (AUTHOR), Williams, Andrew2 (AUTHOR), Halappanavar, Sabina2 (AUTHOR), Malik, Amal I2 (AUTHOR), Luijten, Mirjam3 (AUTHOR), Aubrecht, Jiri4 (AUTHOR), Hyduke, Daniel R.5 (AUTHOR), Fornace, Albert J.6 (AUTHOR), Swartz, Carol D.7 (AUTHOR), Recio, Leslie7 (AUTHOR), Yauk, Carole L.2 (AUTHOR) ivy.moffat@hc-sc.gc.ca
Publikováno v: Critical Reviews in Toxicology. Jan2015, Vol. 45 Issue 1, p1-43. 43p. 5 Diagrams, 10 Charts, 5 Graphs.
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6
Akademický článek
Integrating toxicogenomics into human health risk assessment: Lessons learned from the benzo[ a]pyrene case study.
Autor: Chepelev, Nikolai L.1 (AUTHOR) nikolai.chepelev@hc-sc.gc.ca, Moffat, Ivy D.1,2 (AUTHOR) nikolai.chepelev@hc-sc.gc.ca, Labib, Sarah1 (AUTHOR), Bourdon-Lacombe, Julie1,2 (AUTHOR), Kuo, Byron1 (AUTHOR), Buick, Julie K.1 (AUTHOR), Lemieux, France2 (AUTHOR), Malik, Amal I.1 (AUTHOR), Halappanavar, Sabina1 (AUTHOR), Williams, Andrew1 (AUTHOR), Yauk, Carole L.1 (AUTHOR) nikolai.chepelev@hc-sc.gc.ca
Publikováno v: Critical Reviews in Toxicology. Jan2015, Vol. 45 Issue 1, p44-52. 9p. 2 Diagrams, 1 Chart.
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7
Akademický článek
Thyroid hormone-regulated gene expression in juvenile mouse liver: identification of thyroid response elements using microarray profiling and in silico analyses.
Publikováno v: BMC Genomics. 2011 Supplement 2, Vol. 12 Issue Suppl 2, p634-648. 15p. 1 Color Photograph, 4 Charts, 3 Graphs.
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8
Akademický článek
Toxicogenomic Analysis of Mainstream Tobacco Smoke-Exposed Mice Reveals Repression of Plasminogen Activator Inhibitor-1 Gene in Heart.
Autor: Halappanavar, Sabina1 (AUTHOR) shalappa@hc-sc.gc.ca, Stampfli, Martin R.2 (AUTHOR), Berndt-Weis, Lynn1 (AUTHOR), Williams, Andrew3 (AUTHOR), Douglas, George R.1 (AUTHOR), Yauk, Carole L.1 (AUTHOR)
Publikováno v: Inhalation Toxicology. Jan2009, Vol. 21 Issue 1, p78-85. 8p. 1 Black and White Photograph, 1 Chart, 3 Graphs.
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9
Akademický článek
Improving confidence in (Q)SAR predictions under Canada’s Chemicals Management Plan – a chemical space approach.
Autor: Kulkarni, S. A., Benfenati, E., Barton-Maclaren, T. S.
Publikováno v: SAR & QSAR in Environmental Research; Oct2016, Vol. 27 Issue 10, p851-863, 13p
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