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pro vyhledávání: '"Lynn Amon"'
Autor:
Daniel F. Hoft, Azra Blazevic, Asmir Selimovic, Aldin Turan, Jan Tennant, Getahun Abate, John Fulkerson, Daniel E. Zak, Robert Walker, Bruce McClain, Jerry Sadoff, Judy Scott, Barbara Shepherd, Jasur Ishmukhamedov, David A. Hokey, Veerabadran Dheenadhayalan, Smitha Shankar, Lynn Amon, Garnet Navarro, Rebecca Podyminogin, Alan Aderem, Lew Barker, Michael Brennan, Robert S. Wallis, Anne A. Gershon, Michael D. Gershon, Sharon Steinberg
Publikováno v:
EBioMedicine, Vol 7, Iss C, Pp 278-286 (2016)
Background: We report a first-in-human trial evaluating safety and immunogenicity of a recombinant BCG, AERAS-422, over-expressing TB antigens Ag85A, Ag85B, and Rv3407 and expressing mutant perfringolysin. Methods: This was a randomized, double-blind
Externí odkaz:
https://doaj.org/article/247fad6c17484ca8917acc90c57cd726
Publikováno v:
The Journal of Immunology. 196:65.6-65.6
Mycobacterium tuberculosis (Mtb) continues to be a major global health problem, infecting nearly one-third of the world’s population and leading to around 1.5 million deaths each year. Current drug regimens last 6–9 months and there is still no e
Autor:
Jarrod S Johnson, Sasha Lucas, Stephanie Skelton, Rodolfo Nazitto, Lynn Amon, Dan R Littman, Alan Aderem
Publikováno v:
The Journal of Immunology. 196:61.8-61.8
Myeloid dendritic cells (DCs) have the innate capacity to sense pathogens and mount counteroffensive responses, which include the production of type I and type III interferons (IFN). In the case of HIV-1 infection, DCs can internalize and present vir