Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Lynn A. Megeney"'
Autor:
Patrick G. Burgon, Jonathan J. Weldrick, Omar Mohamed Sayed Ahmed Talab, Muhammad Nadeer, Michail Nomikos, Lynn A. Megeney
Publikováno v:
Cells, Vol 12, Iss 18, p 2324 (2023)
Heart disease remains a global leading cause of death and disability, necessitating a comprehensive understanding of the heart’s development, repair, and dysfunction. This review surveys recent discoveries that explore the developmental transition
Externí odkaz:
https://doaj.org/article/41fdb186ec7a4270b4f48f2ceccc1702
Autor:
Ryan A. V. Bell, Mohammad H. Al-Khalaf, Steve Brunette, Dalal Alsowaida, Alphonse Chu, Hina Bandukwala, Georg Dechant, Galina Apostolova, F. Jeffrey Dilworth, Lynn A. Megeney
Publikováno v:
Cells, Vol 11, Iss 6, p 966 (2022)
The induction of lineage-specific gene programs are strongly influenced by alterations in local chromatin architecture. However, key players that impact this genome reorganization remain largely unknown. Here, we report that the removal of the specia
Externí odkaz:
https://doaj.org/article/401e503390fc466fa68ff97a37303090
Autor:
Didac Carmona-Gutierrez, Maria Anna Bauer, Andreas Zimmermann, Andrés Aguilera, Nicanor Austriaco, Kathryn Ayscough, Rena Balzan, Shoshana Bar-Nun, Antonio Barrientos, Peter Belenky, Marc Blondel, Ralf J. Braun, Michael Breitenbach, William C. Burhans, Sabrina Büttner, Duccio Cavalieri, Michael Chang, Katrina F. Cooper, Manuela Côrte-Real, Vítor Costa, Christophe Cullin, Ian Dawes, Jörn Dengjel, Martin B. Dickman, Tobias Eisenberg, Birthe Fahrenkrog, Nicolas Fasel, Kai-Uwe Fröhlich, Ali Gargouri, Sergio Giannattasio, Paola Goffrini, Campbell W. Gourlay, Chris M. Grant, Michael T. Greenwood, Nicoletta Guaragnella, Thomas Heger, Jürgen Heinisch, Eva Herker, Johannes M. Herrmann, Sebastian Hofer, Antonio Jiménez-Ruiz, Helmut Jungwirth, Katharina Kainz, Dimitrios P. Kontoyiannis, Paula Ludovico, Stéphen Manon, Enzo Martegani, Cristina Mazzoni, Lynn A. Megeney, Chris Meisinger, Jens Nielsen, Thomas Nyström, Heinz D. Osiewacz, Tiago F. Outeiro, Hay-Oak Park, Tobias Pendl, Dina Petranovic, Stephane Picot, Peter Polčic, Mark Ramsdale, Mark Rinnerthaler, Patrick Rockenfeller, Christoph Ruckenstuhl, Raffael Schaffrath, Maria Segovia, Fedor F. Severin, Amir Sharon, Stephan J. Sigrist, Cornelia Sommer-Ruck, Maria João Sousa, Johan M. Thevelein, Karin Thevissen, Vladimir Titorenko, Michel B. Toledano, Mick Tuite, F.-Nora Vögtle, Benedikt Westermann, Joris Winderickx, Silke Wissing, Stefan Wölfl, Zhaojie J. Zhang, Richard Y. Zhao, Bing Zhou, Lorenzo Galluzzi, Guido Kroemer, Frank Madeo
Publikováno v:
Microbial Cell, Vol 5, Iss 1, Pp 4-31 (2018)
Elucidating the biology of yeast in its full complexity has major implications for science, medicine and industry. One of the most critical processes determining yeast life and physiology is cellular demise. However, the investigation of yeast cell d
Externí odkaz:
https://doaj.org/article/7204719614c446e08c16d57347cd80b5
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 23 (2018)
Background Cardiac hypertrophy is an adaptive remodeling event that may improve or diminish contractile performance of the heart. Physiologic and pathologic hypertrophy yield distinct outcomes, yet both are dependent on caspase‐directed proteolysis
Externí odkaz:
https://doaj.org/article/eaef5e37e76a4f86b112274e7fa0bd60
Autor:
Amit Shrestha, Lynn A. Megeney
Publikováno v:
Microbial Cell, Vol 2, Iss 12, Pp 458-465 (2015)
Protein quality control or proteostasis is an essential determinant of basic cell health and aging. Eukaryotic cells have evolved a number of proteostatic mechanisms to ensure that proteins retain functional conformation, or are rapidly degraded when
Externí odkaz:
https://doaj.org/article/1ff270bb874a424b86005beb1fb61158
Autor:
Amit eShrestha, Lynn A. Megeney
Publikováno v:
Frontiers in Oncology, Vol 2 (2012)
The activation of caspase proteases and the targeting of protein substrates act as key steps in the engagement and conduct of apoptosis/programmed cell death. However, the discovery of caspase involvement in diverse non-apoptotic cellular functions s
Externí odkaz:
https://doaj.org/article/ec68a2776370489c9dba3c3b89e92fac
Publikováno v:
Trends in Cell Biology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8adc66dbce17f1bf05e7c96474145e3
https://doi.org/10.1016/j.tcb.2023.03.002
https://doi.org/10.1016/j.tcb.2023.03.002
Autor:
Kiran Nakka, Sarah Hachmer, Zeinab Mokhtari, Radmila Kovac, Hina Bandukwala, Clara Bernard, Yuefeng Li, Guojia Xie, Chengyu Liu, Magid Fallahi, Lynn A. Megeney, Julien Gondin, Bénédicte Chazaud, Marjorie Brand, Xiaohui Zha, Kai Ge, F. Jeffrey Dilworth
Publikováno v:
Science (New York, N.Y.). 377(6606)
Muscle stem cells (MuSCs) reside in a specialized niche that ensures their regenerative capacity. Although we know that innate immune cells infiltrate the niche in response to injury, it remains unclear how MuSCs adapt to this altered environment for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec37acd6420be7bb466dd1c377167eb
https://pubmed.ncbi.nlm.nih.gov/35926040
https://pubmed.ncbi.nlm.nih.gov/35926040
Autor:
Brian D. Larsen, Jan Benada, Philip Yuk Kwong Yung, Ryan A. V. Bell, George Pappas, Vaclav Urban, Johanna K. Ahlskog, Tia T. Kuo, Pavel Janscak, Lynn A. Megeney, Simon J. Elsässer, Jiri Bartek, Claus S. Sørensen
Genotoxic therapy such as radiation serves as a frontline cancer treatment, yet acquired resistance that leads to tumor reoccurrence is frequent. We found that cancer cells maintain viability during irradiation by reversibly increasing genome-wide DN
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f94a98c77fd839512eb03c92cbac49d7
Autor:
Lynn A. Megeney, Charis Putinski
Publikováno v:
Biochemistry of Apoptosis and Autophagy ISBN: 9783030787981
Biochemistry of Apoptosis and Autophagy
Biochemistry of Apoptosis and Autophagy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::68f86007e9b61e2eb1fa6db7d0032d45
https://doi.org/10.1007/978-3-030-78799-8_5
https://doi.org/10.1007/978-3-030-78799-8_5