Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lynn A Sheldon"'
Publikováno v:
PLoS ONE, Vol 4, Iss 8, p e6766 (2009)
Chronic exposure to inorganic arsenic (iAs) found in the environment is one of the most significant and widespread environmental health risks in the U.S. and throughout the world. It is associated with a broad range of health effects from cancer to d
Externí odkaz:
https://doaj.org/article/e9c8889157804481bdaada72dfaebf65
Autor:
Lynn A. Sheldon
The regulation of cell cycle progression by steroid hormones and growth factors is important for maintaining normal cellular processes including development and cell proliferation. Deregulated progression through the G1/S and G2/M cell cycle transiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1471b52bf73c9083d9e29ba7412ef740
https://europepmc.org/articles/PMC5731421/
https://europepmc.org/articles/PMC5731421/
Publikováno v:
Molecular and Cellular Biology. 19:8146-8157
We utilized the mouse mammary tumor virus (MMTV) long terminal repeat (LTR) in vivo to understand how the interaction of the glucocorticoid receptor (GR) with a nucleosome-assembled promoter allows access of factors required for the transition from a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d2de7538a2a80386fbb612cdcf3fa80
https://doi.org/10.1128/mcb.19.12.8146
https://doi.org/10.1128/mcb.19.12.8146
Autor:
Ronald L. Wilder, Lynn A. Sheldon, Constance E. Brinckerhoff, David R. Burgess, Mary C. Benoit
Publikováno v:
Ciba Foundation Symposium 113-Retinoids, Differentiation and Disease ISBN: 9780470720943
Ciba Foundation Symposium 113-Retinoids, Differentiation and Disease
Ciba Foundation Symposium 113-Retinoids, Differentiation and Disease
In rheumatoid arthritis synovial tissue proliferates and destroys articular cartilage, bone and tendons. Collagenase is a major mediator of the connective tissue degradation. This enzyme is produced in large quantities by rheumatoid tissue and its sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29aa1eb70a278958357461273bfafdd2
https://doi.org/10.1002/9780470720943.ch12
https://doi.org/10.1002/9780470720943.ch12
Publikováno v:
The Journal of biological chemistry. 276(35)
Acetylation of lysines in histones H3 and H4 N-terminal tails is associated with transcriptional activation and deacetylation with repression. Our studies with the mouse mammary tumor virus (MMTV) promoter in chromatin show significant levels of acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10b897325ce17fde1ca26a1b972dff40
https://pubmed.ncbi.nlm.nih.gov/11448945
https://pubmed.ncbi.nlm.nih.gov/11448945
Autor:
Robert E. Kingston, Lynn A. Sheldon
Publikováno v:
Genesdevelopment. 7(8)
HSF2, one of the heat shock transcription factors in mammalian cells, is localized to the cytoplasm during normal growth and moves to the nucleus upon activation. Heat shock transcription factors in metazoans contain four hydrophobic heptad repeat se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc0ac2e09c2f945d86707a276962f59
https://pubmed.ncbi.nlm.nih.gov/8339932
https://pubmed.ncbi.nlm.nih.gov/8339932
Autor:
Edward D. Harris, Robert H. Gross, Robert C. Jackson, Hideaki Nagase, Constance E. Brinckerhoff, Lynn A. Sheldon
Publikováno v:
Biochemistry. 21:2674-2679
We studied mechanisms governing production of the neutral proteinase collagenase by synovial cells. We used a model system of monolayer cultures of rabbit synovial fibroblasts stimulated to produce collagenase by treatment with phorbol myristate acet
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ebec6503d154f4857f9ed5f36d27d259
https://doi.org/10.1021/bi00540a015
https://doi.org/10.1021/bi00540a015
Autor:
Eugene E. Nattie, Lynn A. Sheldon
Publikováno v:
Life Sciences. 30:1129-1133
Compared to littermate controls, unstressed Jimpy mice have higher brain water, sodium, potassium and chloride contents and lower carbonic anhydrase activity. When stressed by CO2 to produce a respiratory acidosis or by injection of distilled water t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c00bcd08816ad0de7dafa72dbe8c422
https://doi.org/10.1016/0024-3205(82)90534-3
https://doi.org/10.1016/0024-3205(82)90534-3
To facilitate our studies on the mechanisms controlling collagenase production at a molecular level in rabbit synovial fibroblasts, we have constructed a cDNA library using mRNAs isolated from cells induced with crystals of monosodium urate monohydra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f77987f4bc8208f52d157a2faa79869e
https://europepmc.org/articles/PMC345420/
https://europepmc.org/articles/PMC345420/