Zobrazeno 1 - 10
of 71
pro vyhledávání: '"Lynn Feun"'
Autor:
Alexis R. Narvaez-Rojas, Samantha Linhares, Shaina Sedighim, Kyle Daniel Klingbeil, Clara Milikowski, George Elgart, Natalia Jaimes, Lynn Feun, Jose Lutzky, Gabriel De la Cruz Ku, Eli Avisar, Mecker G. Möller
Publikováno v:
Heliyon, Vol 10, Iss 18, Pp e37224- (2024)
Background: Previous studies have reported cases of primary melanoma of the breast parenchyma (PMBP), but the pathogenesis of this disease remains poorly understood. We review the presentation and outcomes of reported cases and provide detailed patho
Externí odkaz:
https://doaj.org/article/c8c98a52660f488795cf89873117a8ab
Autor:
Gregory A Daniels, Sigrun Hallmeyer, Mark Grose, Jon Richards, Mark Faries, Brendan D Curti, Kim A Margolin, Yiwei Zhang, Lynn Feun, Anlong Li, John R Hyngstrom, Robert H I Andtbacka
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 12 (2022)
Background Intratumoral administration of V937, a bioselected, genetically unmodified coxsackievirus A21, has previously demonstrated antitumor activity in patients with advanced melanoma as monotherapy and in combination with the programmed cell dea
Externí odkaz:
https://doaj.org/article/9f10038a20424ab08d0ae2615bc3df12
Autor:
Kim Margolin, Robert HI Andtbacka, Carlo Bifulco, Gregory Daniels, Sigrun Hallmeyer, Mark Grose, Jon Richards, Mark Faries, Yiwei Zhang, John Hyngstrom, Lynn Feun, Anlong Li
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/d81f83013c03478aa4903796a0f4c4ae
Autor:
Merve Hasanov, Denái R. Milton, William H. Sharfman, Bret Taback, Lee D. Cranmer, Gregory A Daniels, Lawrence Flaherty, Sigrun Hallmeyer, Mohammed Milhem, Lynn Feun, Ralph Hauke, Gary Doolittle, Nancy Gregory, Sapna Patel
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Combination immunotherapy with sequential administration may enhance metastatic melanoma (MM) patients with long-term disease control. High Dose Aldesleukin/Recombinant Interleukin-2 (HD rIL-2) and ipilimumab (IPI) offer complementary mechanisms agai
Externí odkaz:
https://doaj.org/article/8301b9196dbd4b3ab906e344ff9c4301
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss Suppl 3 (2020)
Externí odkaz:
https://doaj.org/article/c62fee412612401a8b0fa99714249c3f
Autor:
Pablo Eduardo Puente, Dan Nguyen, Niramol Savaraj, Chunjing Wu, Medhi Wangpaichitr, Stephane Roche, Guangkuan Zhao, Alexis Richaud, Jose Lutzky, Leonel Hernandez Aya, Mecker Moller, Jessica Crystal, Neha Goel, Lynn Feun
Publikováno v:
Cancer Research. 83:4114-4114
Immune check point inhibitor(s) have become a main stay of treatment for melanoma regardless of its mutational status. However, not all patients respond to treatment. In fact, only 40-60% respond to treatment. Currently, only PD-L1/PD-1 expression an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::84b43e8a9c2050ea7929914c23335e13
https://doi.org/10.1158/1538-7445.am2023-4114
https://doi.org/10.1158/1538-7445.am2023-4114
Autor:
Derek Isrow, Karlos Z. Oregel, Javier Cortes, Henry Gomez, Clara Milikowski, Lynn Feun, Orlando Silva
Publikováno v:
Clinical Medicine Insights: Oncology, Vol 2014, Iss 8, Pp 87-90 (2014)
Externí odkaz:
https://doaj.org/article/ff0ffaa90f5042a5b80962db4db21c15
Autor:
Sydney Spector, Chunjing Wu, Dan Nguyen, George Theodore, Ashley Garcia, Lynn Feun, Niramol Savaraj, Medhi Wangpaichitr
Publikováno v:
Cancer Research. 82:2325-2325
We discovered a crucial change common to all platinum resistant (CR) NSCLC cells, wherein a high level of reactive oxygen species (ROS) modulates tumor metabolism. CR cells activate the kynurenine (KYN) pathway (KP) during excessive oxidative stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::025fc5e95634cd6619cf1dc6e9500c5d
https://doi.org/10.1158/1538-7445.am2022-2325
https://doi.org/10.1158/1538-7445.am2022-2325
Autor:
Niramol Savaraj, Chunjing Wu, Marcus Tien Kuo, Min You, Medhi Wangpaichitr, Carlos Robles, Seth Spector, Lynn Feun
Publikováno v:
Drug Target Insights, Vol 2, Pp 119-128 (2007)
It has been shown that melanoma cells do not express argininosuccinate synthetase (ASS) and therefore are unable to synthesize arginine from citrulline. Depleting arginine using pegylated arginine deiminase (ADI-PEG20) results in cell death in melano
Externí odkaz:
https://doaj.org/article/fa24badab1a84ef38a70f6269131d41a
Autor:
Brendan D Curti, Jon Richards, John R Hyngstrom, Gregory A Daniels, Mark Faries, Lynn Feun, Kim A Margolin, Sigrun Hallmeyer, Mark Grose, Yiwei Zhang, Anlong Li, Robert H I Andtbacka
Publikováno v:
Journal for ImmunoTherapy of Cancer. 10:e005224
BackgroundIntratumoral administration of V937, a bioselected, genetically unmodified coxsackievirus A21, has previously demonstrated antitumor activity in patients with advanced melanoma as monotherapy and in combination with the programmed cell deat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11af1c60aab97f973f7486adcffb2754
https://doi.org/10.1136/jitc-2022-005224
https://doi.org/10.1136/jitc-2022-005224