Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Lynn, Wambua"'
Autor:
Lauren B. Arendse, James M. Murithi, Tarrick Qahash, Charisse Flerida A. Pasaje, Luiz C. Godoy, Sumanta Dey, Liezl Gibhard, Sonja Ghidelli-Disse, Gerard Drewes, Marcus Bantscheff, Maria J. Lafuente-Monasterio, Stephen Fienberg, Lynn Wambua, Samuel Gachuhi, Dina Coertzen, Mariëtte van der Watt, Janette Reader, Ayesha S. Aswat, Erica Erlank, Nelius Venter, Nimisha Mittal, Madeline R. Luth, Sabine Ottilie, Elizabeth A. Winzeler, Lizette L. Koekemoer, Lyn-Marie Birkholtz, Jacquin C. Niles, Manuel Llinás, David A. Fidock, Kelly Chibale
Publikováno v:
Science Translational Medicine. 14
Compounds acting on multiple targets are critical to combating antimalarial drug resistance. Here, we report that the human “mammalian target of rapamycin” (mTOR) inhibitor sapanisertib has potent prophylactic liver stage activity, in vitro and i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::983eea505ec8dd3d5aabe3b1a5634b48
https://doi.org/10.1126/scitranslmed.abo7219
https://doi.org/10.1126/scitranslmed.abo7219
Autor:
Lauren B, Arendse, James M, Murithi, Tarrick, Qahash, Charisse Flerida A, Pasaje, Luiz C, Godoy, Sumanta, Dey, Liezl, Gibhard, Sonja, Ghidelli-Disse, Gerard, Drewes, Marcus, Bantscheff, Maria J, Lafuente-Monasterio, Stephen, Fienberg, Lynn, Wambua, Samuel, Gachuhi, Dina, Coertzen, Mariëtte, van der Watt, Janette, Reader, Ayesha S, Aswat, Erica, Erlank, Nelius, Venter, Nimisha, Mittal, Madeline R, Luth, Sabine, Ottilie, Elizabeth A, Winzeler, Lizette L, Koekemoer, Lyn-Marie, Birkholtz, Jacquin C, Niles, Manuel, Llinás, David A, Fidock, Kelly, Chibale
Publikováno v:
Science translational medicine. 14(667)
Compounds acting on multiple targets are critical to combating antimalarial drug resistance. Here, we report that the human "mammalian target of rapamycin" (mTOR) inhibitor sapanisertib has potent prophylactic liver stage activity, in vitro and in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::cc7e03f7694ec0cc5617db67052ed099
https://pubmed.ncbi.nlm.nih.gov/36260689
https://pubmed.ncbi.nlm.nih.gov/36260689
Autor:
Sergio Wittlin, Lynn Wambua, Luyanda Centani, Lauren B. Arendse, Lyn-Marie Birkholtz, Dale Taylor, Kelly Chibale, Janette Reader, Dina Coertzen, Nina Lawrence, Malkeet Kumar, Shoneeze S Renga, Peter Mubanga Cheuka, Stephen Fienberg, Godwin Akpeko Dziwornu, Mariëtte van der Watt
Publikováno v:
ACS Infectious Diseases. 7:34-46
Recent studies on 3,6-diphenylated imidazopyridazines have demonstrated impressive in vitro activity and in vivo efficacy in mouse models of malaria infection. Herein, we report the synthesis and antiplasmodium evaluation of a new series of amidated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df75b11c41574c2c365ab07859345b41
https://doi.org/10.1021/acsinfecdis.0c00481
https://doi.org/10.1021/acsinfecdis.0c00481
Autor:
Peter Mubanga, Cheuka, Luyanda, Centani, Lauren B, Arendse, Stephen, Fienberg, Lynn, Wambua, Shoneeze S, Renga, Godwin Akpeko, Dziwornu, Malkeet, Kumar, Nina, Lawrence, Dale, Taylor, Sergio, Wittlin, Dina, Coertzen, Janette, Reader, Mariette, van der Watt, Lyn-Marie, Birkholtz, Kelly, Chibale
Publikováno v:
ACS infectious diseases. 7(1)
Recent studies on 3,6-diphenylated imidazopyridazines have demonstrated impressive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b31d5f4d31b055cbf9d3b039fa31aaf
https://pubmed.ncbi.nlm.nih.gov/33319990
https://pubmed.ncbi.nlm.nih.gov/33319990