Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Lynn, Slobbe"'
Autor:
Michael R. Eccles, Cherie Stayner, Justin Shields, Thomas Weimbs, Lynn Slobbe, Jonathan M. Shillingford
Publikováno v:
Nephrology. 17:739-747
Aim: Polycystic kidney disease (PKD) in humans involves kidney cyst expansion beginning in utero. Recessive PKD can result in end-stage renal disease (ESRD) within the first decade, whereas autosomal dominant PKD (ADPKD), caused by mutations in the P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12bb0cad3ad10564a386b07a3302858e
https://doi.org/10.1111/j.1440-1797.2012.01639.x
https://doi.org/10.1111/j.1440-1797.2012.01639.x
Autor:
Cherie Stayner, Michael Legge, Michael R. Eccles, Jody Hazlett, Jessica Ineson, Lynn Slobbe, Ewan Robson
Publikováno v:
Journal of Reproduction and Development. 58:490-500
Genomic imprinting confers allele-specific expression in less than 1% of genes, in a parent-of-origin specific fashion. In humans and mice the Peg1/Mest gene (Mest) is maternally repressed, and paternally expressed. Mest is expressed in embryogenic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bade798ad9647f83ccd4da97f3f2710
https://doi.org/10.1262/jrd.11-115a
https://doi.org/10.1262/jrd.11-115a
Publikováno v:
Immunology & Cell Biology. 88:95-98
Animal models indicate that exposure to environmental strains of mycobacteria can modulate immune responses and influence the effectiveness of live mycobacterial vaccines. Here, we describe that between the two recently reported Mycobacterium avium i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63824ae2e9bd64a531c2d21c9369a0f
https://doi.org/10.1038/icb.2009.51
https://doi.org/10.1038/icb.2009.51
Autor:
Lynn Slobbe, Rachel Wilson, Bryce M. Buddle, Sarah L. Young, G.S. Buchan, Geofferey W. de Lisle
Publikováno v:
Infection and Immunity. 75:2833-2840
Prior exposure of a vaccinee to certain species of environmental mycobacteria can prime the immune system against common mycobacterial antigens, which can in turn reduce the subsequent efficacy of live attenuated mycobacterial vaccines (such as Mycob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be07e2005f0b9434e6a0e9ec18ede418
https://doi.org/10.1128/iai.01826-06
https://doi.org/10.1128/iai.01826-06
Publikováno v:
The FASEB Journal. 29
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13acce47a12b4edafdfe44c6de16f91a
https://doi.org/10.1096/fasebj.29.1_supplement.999.7
https://doi.org/10.1096/fasebj.29.1_supplement.999.7
Autor:
Rachel Wilson, Margaret A. Baird, Lynn Slobbe, L. Young, G.S. Buchan, Euan Lockhart, Sarah L. Young, Michelle Wilson, Jonathan Williman
Publikováno v:
Scandinavian Journal of Immunology. 60:363-371
A polyepitope DNA vaccine has the potential to generate protective immune responses to a range of antigens in a single construct. We investigated whether it was possible to obtain responses to individual epitopes from different antigens, directly lin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b90b25be46293050beb9b34403f7599
https://doi.org/10.1111/j.0300-9475.2004.01487.x
https://doi.org/10.1111/j.0300-9475.2004.01487.x
Autor:
Natalie J. Medlicott, Lynn Slobbe, Majid Razzak, G.S. Buchan, Ian G. Tucker, Nigel M. Davies, Euan Lockhart
Publikováno v:
Immunology & Cell Biology. 81:185-191
A single dose vaccine formulation which induces both humoral and cell-mediated immune responses over a prolonged period would provide a potent weapon against infectious disease. We have used a water-in-oil-in-oil, solvent evaporation method for gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::653edb9ea06ce64ae39e3e468e2589c8
https://doi.org/10.1046/j.1440-1711.2003.01155.x
https://doi.org/10.1046/j.1440-1711.2003.01155.x
Autor:
Bryce M. Buddle, Michael A. O’Donnell, Geoff de Lisle, Euan Lockhart, Sarah L. Young, G.S. Buchan, Lynn Slobbe, Yi Luo
Publikováno v:
Immunology & Cell Biology. 80:209-215
Bacillus Calmette Guerin (BCG) has been reported to show variable efficacy as a vaccine against tuberculosis. We demonstrated that the secretion of biologically active IL-2 (rBCG/IL-2),but not IL-18 (rBCG/IL-18), by BCG improves its ability to induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59da22747b61f8578cf3f43445d3b0c4
https://doi.org/10.1046/j.1440-1711.2002.01078.x
https://doi.org/10.1046/j.1440-1711.2002.01078.x
Publikováno v:
The FASEB Journal. 28
The intestinal epithelium is a complex structure consisting of distinct cell types derived from stem cells residing in the crypt base. Here we investigated the spontaneous maturation of organoids grown from human colonic crypts. Crypts were isolated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4a34bb07798b462ea2f3a7eb9a29d02
https://doi.org/10.1096/fasebj.28.1_supplement.1119.2
https://doi.org/10.1096/fasebj.28.1_supplement.1119.2
Publikováno v:
Tuberculosis. 81:115-123
Mycobacterium bovis is frequently seen inside macrophages in vivo. The outcome of M. bovis infection depends on T cell interactions with macrophages, however mycobacteria are thought to be relatively resistant to macrophage killing. Little is known a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbdb94a3a02b3a520263d2cf12d43a82
https://doi.org/10.1054/tube.2000.0280
https://doi.org/10.1054/tube.2000.0280