Zobrazeno 1 - 10
of 395
pro vyhledávání: '"Lynette M Smith"'
Publikováno v:
PLoS ONE, Vol 14, Iss 1, p e0210405 (2019)
INTRODUCTION:In this paper we perform a replication analysis of "Effect of a cash transfer programme for schooling on prevalence of HIV and herpes simplex type 2 in Malawi: a cluster randomised trial" by Sarah Baird and others published in "The Lance
Externí odkaz:
https://doaj.org/article/bc687db729374964a6d679c82f59b346
Publikováno v:
Journal of Statistics and Data Science Education, Pp 1-12 (2024)
In a biostatistics course on clinical trials, one important topic is human research ethics. In this study, an E-Learning module (e-module) was developed to train students in human research ethics. This interactive e-module provides an overview of the
Externí odkaz:
https://doaj.org/article/e642ec3e91494fc288e0e1b1ac45631c
Autor:
Rohita Sinha, Lisa A Weissenburger-Moser, Jennifer L Clarke, Lynette M Smith, Art J Heires, Debra J Romberger, Tricia D LeVan
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0191499 (2018)
Chronic obstructive pulmonary disease (COPD) is an inflammatory disorder characterized by incompletely reversible airflow obstruction. The complexity of the lung microbial community in COPD patients has been highlighted in recent years. Evidence sugg
Externí odkaz:
https://doaj.org/article/72b41894eb6943369d183f0bf051ea9e
Autor:
Pranita Atri, Ashu Shah, Gopalakrishnan Natarajan, Satyanarayana Rachagani, Sanchita Rauth, Koelina Ganguly, Joseph Carmicheal, Dario Ghersi, Jesse L. Cox, Lynette M. Smith, Maneesh Jain, Sushil Kumar, Moorthy P. Ponnusamy, Parthasarathy Seshacharyulu, Surinder K. Batra
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-15 (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) remains highly lethal due to limited therapeutic options and expensive/burdensome drug discovery processes. Utilizing genomic-data-driven Connectivity Mapping (CMAP) to identify a drug closer to real-w
Externí odkaz:
https://doaj.org/article/27698b79b7aa49419b969e281158a44b
Autor:
Partha Mukhopadhyay, Imayavaramban Lakshmanan, Moorthy P Ponnusamy, Subhankar Chakraborty, Maneesh Jain, Priya Pai, Lynette M Smith, Subodh M Lele, Surinder K Batra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e54455 (2013)
INTRODUCTION: Current studies indicate that triple negative breast cancer (TNBC), an aggressive breast cancer subtype, is associated with poor prognosis and an early pattern of metastasis. Emerging evidence suggests that MUC4 mucin is associated with
Externí odkaz:
https://doaj.org/article/ab7b3381d0184e439f605f978eacc75e
Autor:
Sukhwinder Kaur, Subhankar Chakraborty, Michael J Baine, Kavita Mallya, Lynette M Smith, Aaron Sasson, Randall Brand, Sushovan Guha, Maneesh Jain, Uwe Wittel, Shailender K Singh, Surinder K Batra
Publikováno v:
PLoS ONE, Vol 8, Iss 2, p e55171 (2013)
Pancreatic cancer (PC) is lethal malignancy with very high mortality rate. Absence of sensitive and specific marker(s) is one of the major factors for poor prognosis of PC patients. In pilot studies using small set of patients, secreted acute phase p
Externí odkaz:
https://doaj.org/article/0341217466684894a91a62f6d201010c
Autor:
Michael J Baine, Subhankar Chakraborty, Lynette M Smith, Kavita Mallya, Aaron R Sasson, Randall E Brand, Surinder K Batra
Publikováno v:
PLoS ONE, Vol 6, Iss 2, p e17014 (2011)
It is well known that many malignancies, including pancreatic cancer (PC), possess the ability to evade the immune system by indirectly downregulating the mononuclear cell machinery necessary to launch an effective immune response. This knowledge, in
Externí odkaz:
https://doaj.org/article/1d458e23fb7a4d7aa0fe8cc801f6c085
Publikováno v:
Journal of Clinical and Translational Science, Vol 5 (2021)
Abstract Introduction: Rigor and reproducibility are two important cornerstones of medical and scientific advancement. Clinical and translational research (CTR) contains four phases (T1–T4), involving the translation of basic research to humans, t
Externí odkaz:
https://doaj.org/article/53e34fa4a3fa4da898ef2a53eb8757c2
Autor:
Staci L. Haney, Dan Feng, Yashpal S. Chhonker, Michelle L. Varney, Jacob T. Williams, Lynette M. Smith, James B. Ford, Daryl J. Murry, Sarah A. Holstein
Publikováno v:
Drug Development Research. 84:62-74
Rab GTPases are critical regulators of protein trafficking in the cell. To ensure proper cellular localization and function, Rab proteins must undergo a posttranslational modification, termed geranylgeranylation. In the isoprenoid biosynthesis pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba636d175e4847ed957978b02fdcaf1
https://doi.org/10.1002/ddr.22012
https://doi.org/10.1002/ddr.22012
Autor:
Imayavaramban Lakshmanan, Saravanakumar Marimuthu, Sanjib Chaudhary, Parthasarathy Seshacharyulu, Satyanarayana Rachagani, Sakthivel Muniyan, Ramakanth Chirravuri-Venkata, Pranita Atri, Sanchita Rauth, Rama Krishna Nimmakayala, Jawed Akhtar Siddiqui, Shailendra K. Gautam, Ashu Shah, Gopalakrishnan Natarajan, Seema Parte, Namita Bhyravbhatla, Kavita Mallya, Dhanya Haridas, Geoffrey A. Talmon, Lynette M. Smith, Sushil Kumar, Apar Kishor Ganti, Maneesh Jain, Moorthy P. Ponnusamy, Surinder K. Batra
Publikováno v:
Oncogene
MUC16, membrane-bound mucin, plays an oncogenic role in pancreatic ductal adenocarcinoma (PDAC). However, the pathological role of MUC16 in the PDAC progression, tumor microenvironment, and metastasis in cooperation with Kras(G12D) and Trp53(R172H) m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::278ab0d89c58575801acb946fe049053
https://doi.org/10.1038/s41388-022-02493-6
https://doi.org/10.1038/s41388-022-02493-6