Zobrazeno 1 - 10 of 683 pro vyhledávání: '"Lynette C, Daws"'
1
Akademický článek
High Affinity Decynium-22 Binding to Brain Membrane Homogenates and Reduced Dorsal Camouflaging after Acute Exposure to it in Zebrafish
Autor: Georgianna G. Gould, Priscilla A. Barba-Escobedo, Rebecca E. Horton, Lynette C. Daws
Publikováno v: Frontiers in Pharmacology, Vol 13 (2022)
Organic cation transporters (OCTs) are expressed in the mammalian brain, kidney, liver, placenta, and intestines, where they facilitate the transport of cations and other substrates between extracellular fluids and cells. Despite increasing reliance
Externí odkaz: https://doaj.org/article/52d25c4c6ecb42c49b21aab261a85d83
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2
Akademický článek
Faster Serotonin Clearance in CA3 Region of Hippocampus and Antidepressant-like Effect of Decynium-22 in Juvenile Mice Are Putatively Linked to Increased Plasma Membrane Monoamine Transporter Function: Implications for Efficacy of Antidepressants in Juveniles
Autor: Melodi A. Bowman, Jorge A. Gomez, Nathan C. Mitchell, Anne M. Wells, Melissa Vitela, Kyra M. Clarke, Rebecca E. Horton, Wouter Koek, Lynette C. Daws
Publikováno v: Cells, Vol 11, Iss 15, p 2454 (2022)
Selective serotonin reuptake inhibitors (SSRIs) are less efficacious in treating depression in children than in adults. SSRIs block serotonin uptake via the high-affinity, low-capacity serotonin transporter. However, the low-affinity, high-capacity o
Externí odkaz: https://doaj.org/article/1e8fa113ae6d49c6a4e5e94164ae7fa9
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3
Akademický článek
High Salt Intake Lowers Behavioral Inhibition
Autor: T. Lee Gilman, Christina M. George, Mary Ann Andrade, Nathan C. Mitchell, Glenn M. Toney, Lynette C. Daws
Publikováno v: Frontiers in Behavioral Neuroscience, Vol 13 (2019)
Stress-related neuropsychiatric (e.g., anxiety, depression) and cardiovascular diseases are frequently comorbid, though discerning the directionality of their association has been challenging. One of the most controllable risk factors for cardiovascu
Externí odkaz: https://doaj.org/article/bd2e0062b9bc4028ae72357846a21853
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4
Akademický článek
Targeting Serotonin Transporters in the Treatment of Juvenile and Adolescent Depression
Autor: Melodi A. Bowman, Lynette C. Daws
Publikováno v: Frontiers in Neuroscience, Vol 13 (2019)
Depression is a serious public health concern. Many patients are not effectively treated, but in children and adolescents this problem is compounded by limited pharmaceutical options. Currently, the Food and Drug Administration approves only two anti
Externí odkaz: https://doaj.org/article/aa11a0ebad00480b9880a68d121e177a
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10
Role of Organic Cation Transporter 3 and Plasma Membrane Monoamine Transporter in the Rewarding Properties and Locomotor Sensitizing Effects of Amphetamine in Male andFemale Mice
Autor: Nikki J. Clauss, Wouter Koek, Lynette C. Daws
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 13420, p 13420 (2021)
International Journal of Molecular Sciences; Volume 22; Issue 24; Pages: 13420
International Journal of Molecular Sciences
A lack of effective treatment and sex-based disparities in psychostimulant addiction and overdose warrant further investigation into mechanisms underlying the abuse-related effects of amphetamine-like stimulants. Uptake-2 transporters such as organic
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3aea1534ccd5c9eb944218be90f43423
https://www.mdpi.com/1422-0067/22/24/13420
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