Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Lynette Beattie"'
Autor:
Cameron G. Williams, Marcela L. Moreira, Takahiro Asatsuma, Hyun Jae Lee, Shihan Li, Thomas N. Burn, Irving Barrera, Evan Murray, Megan S.F. Soon, Jessica A. Engel, David S. Khoury, Shirley Le, Brooke J. Wanrooy, Dominick Schienstock, Yannick O. Alexandre, Oliver P. Skinner, Rainon Joseph, Lynette Beattie, Scott N. Mueller, Fei Chen, Ashraful Haque
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114754- (2024)
Externí odkaz:
https://doaj.org/article/3eeba6fae4804717be2dfc45ba70fa91
Autor:
Winter A. Okoth, Mei-Fong Ho, Mehfuz Zaman, Emily Cooper, Priyanka Som, Mark Burgess, Maddison Walton, Reshma J. Nevagi, Lynette Beattie, Declan Murphy, Danielle I. Stanisic, Michael F. Good
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTMalaria is a leading cause of illness and death in children under 5 years of age in Sub-Saharan Africa. Currently, there is no highly efficacious malaria vaccine capable of inducing long-lasting immunity. This has increased interest in explor
Externí odkaz:
https://doaj.org/article/58503cf4463f4620890431441d890ccb
Autor:
Nancy Wang, Timothy A Scott, Andreas Kupz, Meghanashree M Shreenivas, Newton G Peres, Dianna M Hocking, Chenying Yang, Leila Jebeli, Lynette Beattie, Joanna R Groom, Thomas P Pierce, Linda M Wakim, Sammy Bedoui, Richard A Strugnell
Publikováno v:
PLoS Pathogens, Vol 19, Iss 9, p e1011666 (2023)
Prior infection can generate protective immunity against subsequent infection, although the efficacy of such immunity can vary considerably. Live-attenuated vaccines (LAVs) are one of the most effective methods for mimicking this natural process, and
Externí odkaz:
https://doaj.org/article/f3d56009cb644d75a2d9d9ab1727aad4
Autor:
Matthias H. Enders, Ganchimeg Bayarsaikhan, Sonia Ghilas, Yu Cheng Chua, Rose May, Maria N. de Menezes, Zhengyu Ge, Peck Szee Tan, Anton Cozijnsen, Vanessa Mollard, Katsuyuki Yui, Geoffrey I. McFadden, Mireille H. Lahoud, Irina Caminschi, Anthony W. Purcell, Ralf B. Schittenhelm, Lynette Beattie, William R. Heath, Daniel Fernandez-Ruiz
Publikováno v:
Current Research in Immunology, Vol 2, Iss , Pp 79-92 (2021)
Thorough understanding of the role of CD4 T cells in immunity can be greatly assisted by the study of responses to defined specificities. This requires knowledge of Plasmodium-derived immunogenic epitopes, of which only a few have been identified, es
Externí odkaz:
https://doaj.org/article/ae70f072848a4eb3bfa16dbb9ca365ca
Autor:
Marcela Montes de Oca, Rajiv Kumar, Fabian de Labastida Rivera, Fiona H. Amante, Meru Sheel, Rebecca J. Faleiro, Patrick T. Bunn, Shannon E. Best, Lynette Beattie, Susanna S. Ng, Chelsea L. Edwards, Glen M. Boyle, Ric N. Price, Nicholas M. Anstey, Jessica R. Loughland, Julie Burel, Denise L. Doolan, Ashraful Haque, James S. McCarthy, Christian R. Engwerda
Publikováno v:
Cell Reports, Vol 17, Iss 2, Pp 399-412 (2016)
The development of immunoregulatory networks is important to prevent disease. However, these same networks allow pathogens to persist and reduce vaccine efficacy. Here, we identify type I interferons (IFNs) as important regulators in developing anti-
Externí odkaz:
https://doaj.org/article/9b05fd1ed67d459e9852bf440f0c5250
Autor:
Daniel Moyo, Lynette Beattie, Paul S. Andrews, John W. J. Moore, Jon Timmis, Amy Sawtell, Stefan Hoehme, Adam T. Sampson, Paul M. Kaye
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Cellular activation in trans by interferons, cytokines, and chemokines is a commonly recognized mechanism to amplify immune effector function and limit pathogen spread. However, an optimal host response also requires that collateral damage associated
Externí odkaz:
https://doaj.org/article/10892fa7b57246f2b60b06f207672862
Autor:
Ismail Sebina, Kylie R James, Megan S F Soon, Lily G Fogg, Shannon E Best, Fabian de Labastida Rivera, Marcela Montes de Oca, Fiona H Amante, Bryce S Thomas, Lynette Beattie, Fernando Souza-Fonseca-Guimaraes, Mark J Smyth, Paul J Hertzog, Geoffrey R Hill, Andreas Hutloff, Christian R Engwerda, Ashraful Haque
Publikováno v:
PLoS Pathogens, Vol 12, Iss 11, p e1005999 (2016)
Parasite-specific antibodies protect against blood-stage Plasmodium infection. However, in malaria-endemic regions, it takes many months for naturally-exposed individuals to develop robust humoral immunity. Explanations for this have focused on antig
Externí odkaz:
https://doaj.org/article/a54be06609244dfbb023d5a998aed957
Correction: Blimp-1-Dependent IL-10 Production by Tr1 Cells Regulates TNF-Mediated Tissue Pathology.
Autor:
Marcela Montes de Oca, Rajiv Kumar, Fabian de Labastida Rivera, Fiona H Amante, Meru Sheel, Rebecca J Faleiro, Patrick T Bunn, Shannon E Best, Lynette Beattie, Susanna S Ng, Chelsea L Edwards, Werner Muller, Erika Cretney, Stephen L Nutt, Mark J Smyth, Ashraful Haque, Geoffrey R Hill, Shyam Sundar, Axel Kallies, Christian R Engwerda
Publikováno v:
PLoS Pathogens, Vol 12, Iss 2, p e1005460 (2016)
Externí odkaz:
https://doaj.org/article/0b3b7f7fe2094524a9b7b7b6914baeab
Autor:
Rebecca J Faleiro, Rajiv Kumar, Patrick T Bunn, Neetu Singh, Shashi Bhushan Chauhan, Meru Sheel, Fiona H Amante, Marcela Montes de Oca, Chelsea L Edwards, Susanna S Ng, Shannon E Best, Ashraful Haque, Lynette Beattie, Louise M Hafner, David Sacks, Susanne Nylen, Shyam Sundar, Christian R Engwerda
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 10, Iss 2, p e0004415 (2016)
Chronic disease caused by infections, cancer or autoimmunity can result in profound immune suppression. Immunoregulatory networks are established to prevent tissue damage caused by inflammation. Although these immune checkpoints preserve tissue funct
Externí odkaz:
https://doaj.org/article/9eee71f26dbd42a5bd3a9f71736f6983
Autor:
John W J Moore, Lynette Beattie, Mohamed Osman, Benjamin M J Owens, Najmeeyah Brown, Jane E Dalton, Asher Maroof, Paul M Kaye
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0163604 (2016)
Recent thymic emigrants (RTEs) represent a source of antigen-naïve T cells that enter the periphery throughout life. However, whether RTEs contribute to the control of chronic parasitic infection and how their potential might be harnessed by therape
Externí odkaz:
https://doaj.org/article/a8c953ddabaf4a779f8c736ee8ed4224