Recombinations in staphylococcal cassette chromosome mec elements compromise the molecular detection of methicillin resistance in Staphylococcus aureus.

Autor: Grant A Hill-Cawthorne, Lyndsey O Hudson, Moataz Fouad Abd El Ghany, Olaf Piepenburg, Mridul Nair, Andrew Dodgson, Matthew S Forrest, Taane G Clark, Arnab Pain

Publikováno v: PLoS ONE, Vol 9, Iss 6, p e101419 (2014)

Clinical laboratories are increasingly using molecular tests for methicillin-resistant Staphylococcus aureus (MRSA) screening. However, primers have to be targeted to a variable chromosomal region, the staphylococcal cassette chromosome mec (SCCmec).

Externí odkaz: https://doaj.org/article/08ca4532b83a40c3972ca99540f252b0

Predictors of Hospitals with Endemic Community-Associated Methicillin-ResistantStaphylococcus aureus

Autor: Lyndsey O. Hudson, Kristen R. Elkins, Richard Alexander, Mark C. Enright, Courtney R. Murphy, Brian G. Spratt, Leah Terpstra, Paul Hannah, Christopher Nguyen, Susan S. Huang, Adrijana Gombosev

Publikováno v: Murphy, CR; Hudson, LO; Spratt, BG; Elkins, K; Terpstra, L; Gombosev, A; et al.(2013). Predictors of hospitals with endemic community-associated methicillin-resistant Staphylococcus aureus. Infection Control and Hospital Epidemiology, 34(6), 581-587. doi: 10.1086/670631. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/71g1m790

Objective.We sought to identify hospital characteristics associated with community-associated methicillin-resistantStaphylococcus aureus(CA-MRSA) carriage among inpatients.Design.Prospective cohort study.Setting.Orange County, California.Participants

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a040c68f59cd5d3bca6304453051339
https://doi.org/10.1086/670631

Association of a lukM-positive clone of Staphylococcus aureus with fatal exudative dermatitis in red squirrels (Sciurus vulgaris)

Autor: T. Blackett, Jean-Philippe Rasigade, Helen Butler, Adrian M. Whatmore, Mark S. Koylass, Nicholas J. Davison, Victor R. Simpson, B. Pichon, Angela M. Kearns, Lyndsey O. Hudson

Publikováno v: Veterinary Microbiology. 162:987-991

Fatal exudative dermatitis (FED) is a recently described condition affecting red squirrels (Sciurus vulgaris) on the Isle of Wight and Jersey (Simpson et al., 2010a). Staphylococcus aureus strains isolated from skin lesions in cases of FED were chara

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d36be6ac0183a8f99f9d1e2fb25470a
https://doi.org/10.1016/j.vetmic.2012.10.025

A genomic portrait of the emergence, evolution, and global spread of a methicillin-resistant staphylococcus aureus pandemic

Autor: J. Ross Fitzgerald, Franziska Layer, Brian G. Spratt, Helena Žemličková, Lyndsey O. Hudson, Mark C. Enright, Robert Hill, Simon R. Harris, Edward J. Feil, Angela McCann, Ian M. Gould, Hermínia de Lencastre, Stephen D. Bentley, Jonathan D. Edgeworth, Li Yang Hsu, Kate Templeton, Alison E. Mather, Julian Parkhill, Francois Balloux, Santiago Castillo-Ramírez, Lucy A. Weinert, Henrik Westh, Birgit Strommenger, Paul R. McAdam, Kevin Kurt, Zhemin Zhou, Mark Achtman, Angela M. Kearns, Matthew T. G. Holden, David M. Aanensen, Ulrich Nübel, Jonathan Cooke, Wolfgang Witte, Geoffrey W. Coombs, Giles Edwards, Vanya Gant, Robert Skov

Publikováno v: Holden, M T G, Hsu, L-Y, Kurt, K, Weinert, L A, Mather, A E, Harris, S R, Strommenger, B, Layer, F, Witte, W, de Lencastre, H, Skov, R, Westh, H, Zemlickova, H, Coombs, G, Kearns, A M, Hill, R L R, Edgeworth, J, Gould, I, Gant, V, Cooke, J, Edwards, G F, McAdam, P, Templeton, K E, McCann, A, Zhou, Z, Castillo-Ramirez, S, Feil, E J, Hudson, L O, Enright, M C, Balloux, F, Aanensen, D M, Spratt, B G, Fitzgerald, J R, Parkhill, J, Achtman, M, Bentley, S D & Nübel, U 2013, ' A genomic portrait of the emergence, evolution, and global spread of a methicillin resistant Staphylococcus aureus pandemic ', Genome Research, vol. 23, no. 4, pp. 653-664 . https://doi.org/10.1101/gr.147710.112
Genome Research

The widespread use of antibiotics in association with high-density clinical care has driven the emergence of drug-resistant bacteria that are adapted to thrive in hospitalised patients. Of particular concern are globally disseminated methicillin-resi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e478e9614bfb81a2f5ee25c07acf2e2
https://eprints.gla.ac.uk/79108/1/79108.pdf

Differences in methicillin-resistant Staphylococcus aureus strains isolated from pediatric and adult patients from hospitals in a large county in California

Autor: Courtney R. Murphy, Lyndsey O. Hudson, Lydia Mikhail, Paul Hannah, Douglas F. Moore, Richard Alexander, Brian G. Spratt, Susan S. Huang, Mark C. Enright, Adrijana Gombosev, Leah Terpstra

Publikováno v: Hudson, LO; Murphy, CR; Spratt, BG; Enright, MC; Terpstra, L; Gombosev, A; et al.(2012). Differences in methicillin-resistant Staphylococcus aureus strains isolated from pediatric and adult patients from hospitals in a large county in California. Journal of Clinical Microbiology, 50(3), 573-579. doi: 10.1128/JCM.05336-11. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/4gv2d4mp

Studies of U.S. epidemics of community- and health care-associated methicillin-resistant Staphylococcus aureus (MRSA) suggested differences in MRSA strains in adults and those in children. Comprehensive population-based studies exploring these differ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fee581e7d0bc5353d0f99e53835eb2e
http://www.escholarship.org/uc/item/4gv2d4mp