Zobrazeno 1 - 10
of 57
pro vyhledávání: '"Lyndsey E. Collins-Praino"'
Autor:
Rudrarup Bhattacharjee, Lachlan A. Jolly, Mark A. Corbett, Ing Chee Wee, Sushma R. Rao, Alison E. Gardner, Tarin Ritchie, Eline J. H. van Hugte, Ummi Ciptasari, Sandra Piltz, Jacqueline E. Noll, Nazzmer Nazri, Clare L. van Eyk, Melissa White, Dani Fornarino, Cathryn Poulton, Gareth Baynam, Lyndsey E. Collins-Praino, Marten F. Snel, Nael Nadif Kasri, Kim M. Hemsley, Paul Q. Thomas, Raman Kumar, Jozef Gecz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-25 (2024)
Abstract We implicated the X-chromosome THOC2 gene, which encodes the largest subunit of the highly-conserved TREX (Transcription-Export) complex, in a clinically complex neurodevelopmental disorder with intellectual disability as the core phenotype.
Externí odkaz:
https://doaj.org/article/f655e25df84a4da1addb5bf08b495565
Autor:
Amy L. Green, Evangeline C. Cowell, Laura M. Carr, Kim Hemsley, Emma Sherratt, Lyndsey E. Collins-Praino, Jillian M. Carr
Publikováno v:
Viruses, Vol 16, Iss 8, p 1330 (2024)
Zika virus (ZIKV) impacts the developing brain. Here, a technique was applied to define, in 3D, developmental changes in the brains of ZIKV-infected mice. Postnatal day 1 mice were uninfected or ZIKV-infected, then analysed by iodine staining and mic
Externí odkaz:
https://doaj.org/article/e5c27d7a6f8f450c93eec305446d9938
Autor:
Frances Corrigan, Alina Arulsamy, Sandy R. Shultz, David K. Wright, Lyndsey E. Collins-Praino
Publikováno v:
Neurotrauma Reports, Vol 4, Iss 1, Pp 41-50 (2023)
Traumatic brain injury (TBI) is associated with persistent impairments in multiple domains, including cognitive and neuropsychiatric function. Previous literature has suggested that the risk of such impairments may differ as a function of the initial
Externí odkaz:
https://doaj.org/article/bb55f13c94134f78a15e88b06b4d186a
Publikováno v:
Frontiers in Neurology, Vol 14 (2023)
IntroductionTraumatic brain injury (TBI) is now known to be a chronic disease, causing ongoing neurodegeneration and linked to increased risk of neurodegenerative motor diseases, such as Parkinson's disease and amyotrophic lateral sclerosis. While th
Externí odkaz:
https://doaj.org/article/2cfb68b2f37b419687a357db09dc751f
Autor:
India Boyton, Sophia C. Goodchild, Dennis Diaz, Aaron Elbourne, Lyndsey E. Collins-Praino, Andrew Care
Publikováno v:
ACS Omega, Vol 7, Iss 1, Pp 823-836 (2021)
Externí odkaz:
https://doaj.org/article/200331d4a83f46b98b6a3255c171942a
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 770 (2023)
The altered expression of known brain Aquaporin (AQP) channels 1, 4 and 9 has been correlated with neuropathological AD progression, but possible roles of other AQP classes in neurological disease remain understudied. The levels of transcripts of all
Externí odkaz:
https://doaj.org/article/dcd8c2bd1e2f4eb3b827c7eae6808989
Autor:
Bianca Guglietti, David A. Hobbs, Bradley Wesson, Benjamin Ellul, Angus McNamara, Simon Drum, Lyndsey E. Collins-Praino
Publikováno v:
Frontiers in Aging Neuroscience, Vol 14 (2022)
Whilst Parkinson’s disease (PD) is typically thought of as a motor disease, a significant number of individuals also experience cognitive impairment (CI), ranging from mild-CI to dementia. One technique that may prove effective in delaying the onse
Externí odkaz:
https://doaj.org/article/ad6166ac2a5045b79caa353e69f71401
Publikováno v:
Frontiers in Aging Neuroscience, Vol 13 (2021)
Cognitive dysfunction, primarily involving impairments in executive function, visuospatial function and memory, is one of the most common non-motor symptoms of Parkinson’s disease (PD). Currently, the only pharmacological treatments available for t
Externí odkaz:
https://doaj.org/article/a042e0095ed04e5bb8d9f3234d323eb8
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 14, Iss , Pp 100242- (2021)
Dementia is one of the leading causes of death worldwide, with tauopathies, a class of diseases defined by pathology associated with the microtubule-enriched protein, tau, as the major contributor. Although tauopathies, such as Alzheimer’s disease
Externí odkaz:
https://doaj.org/article/b5f00114c987481ea67ac6dd43dba5e8
Autor:
Abdalla Z Mohamed, Frances Corrigan, Lyndsey E. Collins-Praino, Stephanie L. Plummer, Neha Soni, Fatima A. Nasrallah
Publikováno v:
NeuroImage: Clinical, Vol 25, Iss , Pp - (2020)
Background: Diffuse traumatic brain injury (TBI) is known to lead to microstructural changes within both white and grey matter detected in vivo with diffusion tensor imaging (DTI). Numerous studies have shown alterations in fractional anisotropy (FA)
Externí odkaz:
https://doaj.org/article/378fc0718ea9422995de01471167f827