Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lyndsey Castle"'
Autor:
Nzelle Delphine Kayem, Sylvanus Okogbenin, Joseph Okoeguale, Mojeed Momoh, Antonia Njoku, Reuben Eifediyi, Xavier Enodiana, Hilary Ngwu, Wilfred Irhiogbe, Yemisi Ighodalo, Thomas Olokor, George Odigie, Lyndsey Castle, Sophie Duraffour, Lisa Oestereich, Prabin Dahal, Proochista Ariana, Stephan Gunther, Peter Horby
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 5, p e0011354 (2023)
BackgroundThere is limited epidemiological evidence on Lassa fever in pregnant women with acute gaps on prevalence, infection incidence, and risk factors. Such evidence would facilitate the design of therapeutic and vaccine trials and the design of c
Externí odkaz:
https://doaj.org/article/ddc659eaf3a14e50b0db9058dda1129b
Autor:
Nzelle Delphine Kayem, Sylvanus Okogbenin, Joseph Okoeguale, Joseph Eigbefoh, Joseph Ikheloa, Reuben Eifediyi, Xavier Enodiana, Olugbenga Emmanuel Olorogbogo, Isoken Aikpokpo, Yemisi Ighodalo, Thomas Olokor, George Odigie, Lyndsey Castle, Sophie Duraffour, Lisa Oestereich, Prabin Dahal, Proochista Ariana, Stephan Gunther, Peter Horby
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 17, Iss 4, p e0011209 (2023)
BackgroundEvidence from previous studies suggest that Lassa fever, a viral haemorrhagic fever endemic to West Africa has high case fatalities, particularly in pregnancy. While there have been remarkable innovations in vaccine development, with some L
Externí odkaz:
https://doaj.org/article/54defe3329e945fd9635cd19c2c54c4e
Autor:
Yeming Wang, Wu Zhong, Alex Salam, Joel Tarning, Qingyuan Zhan, Jian-an Huang, Heng Weng, Changqing Bai, Yanhong Ren, Koichi Yamada, Dayan Wang, Qiang Guo, Qiongqiong Fang, Sakurai Tsutomu, Xiaohui Zou, Haibo Li, Annelies Gillesen, Lyndsey Castle, Cheng Chen, Hongyan Li, Jing Zhen, Binghuai Lu, Jun Duan, Liping Guo, Jinfang Jiang, Ruiyuan Cao, Guohui Fan, Jintong Li, Frederick G. Hayden, Chen Wang, Peter Horby, Bin Cao
Publikováno v:
EBioMedicine, Vol 62, Iss , Pp 103125- (2020)
Background: The pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data are also needed to determine dosage selection for favipiravir trials in COVID-19. Methods: In this dose-escalating
Externí odkaz:
https://doaj.org/article/6c395bf8af184c779dc41bcfd6011bc0
Autor:
Amanda M. Rojek, Kassiani Gkolfinopoulou, Apostolos Veizis, Angeliki Lambrou, Lyndsey Castle, Theano Georgakopoulou, Karl Blanchet, Takis Panagiotopoulos, Peter W. Horby, The Epidemic Diseases Research Group field team
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-8 (2018)
Abstract Background Refugees may have an increased vulnerability to infectious diseases, and the consequences of an outbreak are more severe in a refugee camp. When an outbreak is suspected, access to clinical information is critical for investigator
Externí odkaz:
https://doaj.org/article/eaa12499b2c542739384c0f44bfee693
Autor:
Jake Dunning, Foday Sahr, Amanda Rojek, Fiona Gannon, Gail Carson, Baimba Idriss, Thomas Massaquoi, Regina Gandi, Sebatu Joseph, Hassan K Osman, Timothy J G Brooks, Andrew J H Simpson, Ian Goodfellow, Lucy Thorne, Armando Arias, Laura Merson, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Benjamin Hope-Gill, Mauricio Ferri, Jennifer Grove, Mark Kowalski, Kasia Stepniewska, Trudie Lang, John Whitehead, Piero Olliaro, Mohammed Samai, Peter W Horby, RAPIDE-TKM trial team
Publikováno v:
PLoS Medicine, Vol 13, Iss 4, p e1001997 (2016)
BackgroundTKM-130803, a small interfering RNA lipid nanoparticle product, has been developed for the treatment of Ebola virus disease (EVD), but its efficacy and safety in humans has not been evaluated.Methods and findingsIn this single-arm phase 2 t
Externí odkaz:
https://doaj.org/article/5d847f2d4b774f4e93d2e3fad6719689
Autor:
Jake Dunning, Stephen B Kennedy, Annick Antierens, John Whitehead, Iza Ciglenecki, Gail Carson, Rupa Kanapathipillai, Lyndsey Castle, Rebecca Howell-Jones, Raul Pardinaz-Solis, Jennifer Grove, Janet Scott, Trudie Lang, Piero Olliaro, Peter W Horby, RAPIDE-BCV trial team
Publikováno v:
PLoS ONE, Vol 11, Iss 9, p e0162199 (2016)
BackgroundThe nucleotide analogue brincidofovir was developed to prevent and treat infections caused by double-stranded DNA viruses. Based on in vitro data suggesting an antiviral effect against Ebola virus, brincidofovir was included in the World He
Externí odkaz:
https://doaj.org/article/60c087d0d1b1410393a2f7dcb96ebb68
Autor:
Rindra Randremanana, Reziky Tiandraza Mangahasimbola, Rodrigue N. E. Hasiniatsy, Dominique Razafimandimby, Tiana Razafinambinintsoa, Anna L. Funk, Laurence Baril, Andrew M. Lovering, Randrianirina Frédérique, Minoarisoa Rajerison, Alex P. Salam, Arnaud Fontanet, Mihaja Raberahona, Faraniaina Andrianarintsiferantsoa, Mamy Jean de Dieu Randria, Norosoa Harline Razanajatovo, Voahangy Andrianaivoarimanana, Peter Horby, Eric Bertherat, Prisca Andriantsalama, Rado Rakotomalala, Jean-Michel Heraud, Lyndsey Castle, Bertrand Renaud, Liam Read
Publikováno v:
American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, 2020, 102 (6), pp.1309-1315. ⟨10.4269/ajtmh.19-0576⟩
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2020, 102 (6), pp.1309-1315. ⟨10.4269/ajtmh.19-0576⟩
The American Journal of Tropical Medicine and Hygiene
American Journal of Tropical Medicine and Hygiene, 2020, 102 (6), pp.1309-1315. ⟨10.4269/ajtmh.19-0576⟩
American Journal of Tropical Medicine and Hygiene, American Society of Tropical Medicine and Hygiene, 2020, 102 (6), pp.1309-1315. ⟨10.4269/ajtmh.19-0576⟩
The American Journal of Tropical Medicine and Hygiene
International audience; In late 2017, Madagascar experienced a large urban outbreak of pneumonic plague, the largest outbreak to date this century. During the outbreak, there were widespread reports of plague patients presenting with atypical symptom
Autor:
Lyndsey Castle, Yanhong Ren, Qiang Guo, Frederick G. Hayden, Guohui Fan, Changqing Bai, Jinfang Jiang, Chen Wang, Alex P. Salam, Annelies Gillesen, Dayan Wang, Liping Guo, Jing Zhen, Qiongqiong Fang, Peter Horby, Jun Duan, Jian-An Huang, Ruiyuan Cao, Qingyuan Zhan, Cheng Chen, Jintong Li, Sakurai Tsutomu, Hongyan Li, Xiaohui Zou, Heng Weng, Haibo Li, Bin Cao, Yeming Wang, Koichi Yamada, Joel Tarning, Wu Zhong, Binghuai Lu
Publikováno v:
EBioMedicine
EBioMedicine, Vol 62, Iss, Pp 103125-(2020)
EBioMedicine, Vol 62, Iss, Pp 103125-(2020)
Background: The pharmacokinetics and appropriate dose regimens of favipiravir are unknown in hospitalized influenza patients; such data are also needed to determine dosage selection for favipiravir trials in COVID-19. Methods: In this dose-escalating
Autor:
Michael Butler, Alex P. Salam, N D Kayem, Peter Horby, Anna Carlqvist, Lang’o Odondi, Lyndsey Castle, Emily Liddiard, Amanda Rojek, Kasia Stepniewska, Ahmed Elhussain, Robert J. Ragotte
Publikováno v:
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
Background Over 28 000 individuals were infected with Ebola virus during the West Africa (2013–2016) epidemic, yet there has been criticism of the lack of robust clinical descriptions of Ebola virus disease (EVD) illness from that outbreak. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc379d5204d18ee14e126a2cf14bdd5
https://ora.ox.ac.uk/objects/uuid:944fe4ad-6b62-408d-bc2b-36d89c8b9146
https://ora.ox.ac.uk/objects/uuid:944fe4ad-6b62-408d-bc2b-36d89c8b9146
Autor:
Steven A R Webb, Srinivas Murthy, Laura Merson, M. W. George, Gail Carson, Raul Pardinaz-Solis, Genevieve K. O'Neill, Lyndsey Castle, Kajsa-Stina Longuere, Peter Horby
Publikováno v:
International Journal of Infectious Diseases. 53