Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lyndsay, Avery"'
Autor:
Lyndsay Avery, Tanner F. Robertson, Christine F. Wu, Nathan H. Roy, Samuel D. Chauvin, Eric Perkey, Ashley Vanderbeck, Ivan Maillard, Janis K. Burkhardt
Publikováno v:
Frontiers in Immunology, Vol 12 (2022)
X-linked moesin associated immunodeficiency (X-MAID) is a primary immunodeficiency disease in which patients suffer from profound lymphopenia leading to recurrent infections. The disease is caused by a single point mutation leading to a R171W amino a
Externí odkaz:
https://doaj.org/article/5d9b6894ef484ac99865935e08f454e1
Autor:
Angela M. Gocher-Demske, Jian Cui, Andrea L. Szymczak-Workman, Kate M. Vignali, Julianna N. Latini, Gwen P. Pieklo, Jesse C. Kimball, Lyndsay Avery, Ellyse M. Cipolla, Brydie R. Huckestein, Lee Hedden, Marlies Meisel, John F. Alcorn, Lawrence P. Kane, Creg J. Workman, Dario A. A. Vignali
Publikováno v:
Nat Immunol
Regulatory T (T(reg)) cells are an immunosuppressive population that are required to maintain peripheral tolerance and prevent tissue damage from immunopathology, via anti-inflammatory cytokines, inhibitor receptors and metabolic disruption. Here we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::317856fa71787b2cd7f75b69af66d144
https://doi.org/10.1038/s41590-023-01453-w
https://doi.org/10.1038/s41590-023-01453-w
Publikováno v:
eLife, Vol 9 (2020)
T cell activation by dendritic cells (DCs) involves forces exerted by the T cell actin cytoskeleton, which are opposed by the cortical cytoskeleton of the interacting antigen-presenting cell. During an immune response, DCs undergo a maturation proces
Externí odkaz:
https://doaj.org/article/c2970352579946319bfe16a53cf24405
Autor:
Shankar Revu, Lawrence P. Kane, Mandy J. McGeachy, Itay Raphael, Catherine H. Poholek, William F. Hawse, Gerard Hernandez-Mir, Lyndsay Avery
Publikováno v:
J Immunol
β-site amyloid precursor protein-cleaving enzyme 1 (BACE1) is best known for its role in Alzheimer's disease amyloid plaque formation but also contributes to neurodegenerative processes triggered by CNS injury. In this article, we report that BACE1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a173d3495a15b65229eba25409d2870
https://doi.org/10.4049/jimmunol.1800363
https://doi.org/10.4049/jimmunol.1800363
Autor:
Ivan Maillard, Pragati Chengappa, Ryan J. Petrie, Nathan H. Roy, Daniela Gómez Atria, Janis K. Burkhardt, Christine F Wu, Lyndsay Avery, Tanner F. Robertson
Publikováno v:
The Journal of Cell Biology
Robertson et al. show that unlike T cells responding to conventional chemokines, T cells responding to the lipid chemoattractant S1P utilize a bleb-based mode of motility. This response involves myosin-induced increases in intracellular pressure and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09177ffdca6f08e8000e0995149c0001
https://doi.org/10.1083/jcb.202007182
https://doi.org/10.1083/jcb.202007182
Autor:
Angela Marie Gocher, Jian Cui, Andrea Szymczak-Workman, Kate Vignali, Julianna N Latini, Gwen P Pieklo, Lyndsay Avery, Ellyse L Cipolla, Brydie R Huckestein, Lee Hedden, Marlies Meisel, John F Alcorn, Lawrence P Kane, Creg J. Workman, Dario A. A. Vignali
Publikováno v:
The Journal of Immunology. 208:53.23-53.23
Regulatory T cells (Tregs) are an immunosuppressive cell population that inhibits immune cell function to maintain peripheral tolerance and homeostasis. We have previously shown that Treg-- response to interferon gamma (IFNγ) is required for respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::651bc8c0ddbdb5afe1d2f40137c3e668
https://doi.org/10.4049/jimmunol.208.supp.53.23
https://doi.org/10.4049/jimmunol.208.supp.53.23
Autor:
Paul R. Kinchington, Benjamin R. Treat, Lyndsay Avery, Lawrence P. Kane, Anthony J. St. Leger, Kate L. Carroll, Robert L. Hendricks
Publikováno v:
Journal of Virology. 94
Herpes simplex virus 1 (HSV-1) causes a lifelong infection of neurons that innervate barrier sites like the skin and mucosal surfaces like the eye. After primary infection of the cornea, the virus enters latency within the trigeminal ganglion (TG), f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::543020629e320807a574e0033180b2db
https://doi.org/10.1128/jvi.01132-19
https://doi.org/10.1128/jvi.01132-19
Autor:
Shuchi Smita, Lawrence P. Kane, Rachael A. Gordon, Greg M. Delgoffe, Ashley V. Menk, Mark J. Shlomchik, Lyndsay Avery, Jeremy S. Tilstra, Maria Chikina
Publikováno v:
Journal of Clinical Investigation. 128:4884-4897
While T cells are important for the pathogenesis of systemic lupus erythematosus (SLE) and lupus nephritis, little is known about how T cells function after infiltrating the kidney. The current paradigm suggests that kidney-infiltrating T cells (KITs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1ef630fb710336dd441415a153a8afe
https://doi.org/10.1172/jci120859
https://doi.org/10.1172/jci120859
Publikováno v:
The Journal of Immunology. 198:640-644
There is growing appreciation that cellular metabolic and bioenergetic pathways do not play merely passive roles in activated leukocytes. Rather, metabolism has important roles in controlling cellular activation, differentiation, survival, and effect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb4ef86d4194fa5275ae3e7c0eaf1d98
https://doi.org/10.4049/jimmunol.1601150
https://doi.org/10.4049/jimmunol.1601150