Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Lyndon D. Su"'
Publikováno v:
Journal of the American Academy of Dermatology. 67:e187-e193
Background Richter syndrome (RS) is large-cell transformation of chronic lymphocytic leukemia (CLL). It commonly involves lymph nodes and bone marrow, but may rarely manifest in skin. Certain triggering factors, such as Epstein-Barr virus infection a
Comparison of CD23 staining patterns in Merkel cell carcinoma and non-cutaneous small cell carcinoma
Publikováno v:
Journal of Cutaneous Pathology. 36:206-210
Background: During our daily practice, we observed that cluster designation 23 (CD23) (clone BU38) labels Merkel cells in normal skin. In this study, we examined the expression of CD23 in Merkel cell carcinoma (MCC) and assessed its usefulness in dis
Publikováno v:
Human Pathology. 39:1614-1620
gamma-H2AX is a marker of activated DNA damage and is overexpressed in many malignancies and their precursor lesions. Previous studies have demonstrated the expression of gamma-H2AX in melanoma and dysplastic nevus, but its diagnostic and prognostic
Publikováno v:
Human Pathology. 39:557-563
MUM1 is a member of the interferon regulatory factor family of transcription factors. It is normally expressed in plasma cells, late B cells, and activated T cells, and has been described in several B-cell malignancies. Although its expression has be
Publikováno v:
Journal of Cutaneous Pathology. 34:597-600
Background: Enhancer of zeste homolog 2 (EZH2), a polycombgroup protein that regulates the cell cycle, has recently been implicatedin the progression of several human cancers. We sought to determinethe pattern of EZH2 expression in benign and maligna
Publikováno v:
Journal of Cutaneous Pathology. 34:386-391
Background: Recent studies have demonstrated telomerase expression in ophthalmologic sebaceous carcinoma and have suggested possible diagnostic utility in distinguishing these neoplasms from sebaceous adenomas. The aim of this study was to evaluate t
Autor:
Lori Lowe, Lyndon D. Su, Doug Fullen, Michael S. Sabel, Hidde M. Kroon, Alfred E. Chang, Vincent M. Cimmino, Timothy D. Johnson, Sandra L. Wong
Publikováno v:
Journal of Surgical Oncology. 95:623-628
Introduction: Many surgeons use the ‘‘10% rule’’ to define whether a lymph node is a sentinel node (SLN) when staging malignant melanoma. However, this increases the number of SLN removed and the time and cost of the procedure. We examined th
Autor:
Alfred E. Chang, Michael S. Sabel, Timothy M. Johnson, Jonathan B. McHugh, Lyndon D. Su, Sandra L. Wong, Vincent M. Cimmino, Kent A. Griffith, Jennifer L. Schwartz
Publikováno v:
Annals of Surgical Oncology. 13:1216-1223
Truncal melanoma involving metastases to multiple lymph node basins has a much worse prognosis than tumor involvement of a single lymph node basin. Recent results also suggest that, independently of the status of lymph node involvement, patients with
Autor:
Lyndon D. Su, Darius J. Karimipour, Timothy M. Johnson, Douglas R. Fullen, Lori Lowe, Vernon K. Sondak, Ted A. Hamilton
Publikováno v:
Journal of the American Academy of Dermatology. 50:759-764
Background Sentinel lymph node (SLN) biopsy in melanoma is an increasingly used procedure. Pathologic evaluation of SLNs using immunohistochemistry improves diagnostic accuracy, yet no universally accepted standard protocol for pathologic processing
Autor:
Timothy M. Johnson, Lyndon D. Su, Vernon K. Sondak, Jennifer L. Schwartz, Lori Lowe, Timothy S. Wang, Vincent Cimmino, Douglas R. Fullen
Publikováno v:
Cancer. 100:598-604
BACKGROUND Desmoplastic and neurotropic melanoma (DNMM) occasionally metastasizes to regional lymph nodes and extranodal sites. The value of sentinel lymph node biopsy (SLNB) has not been demonstrated clearly for patients with DNMM. The authors repor