Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lyndall J. Briggs"'
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137700 (2015)
The N-isopropylammelide isopropylaminohydrolase from Pseudomonas sp. strain ADP, AtzC, provides the third hydrolytic step in the mineralization of s-triazine herbicides, such as atrazine. We obtained the X-ray crystal structure of AtzC at 1.84 Å wit
Externí odkaz:
https://doaj.org/article/d9e36db239714037abd55491391a1b0e
Publikováno v:
Acta Crystallographica. Section F, Structural Biology Communications
The amidase domain of the allophanate hydrolase AtzF from Pseudomonas sp. strain ADP has been crystallized and preliminary X-ray diffraction data have been collected.
The allophanate hydrolase from Pseudomonas sp. strain ADP was expressed and pu
The allophanate hydrolase from Pseudomonas sp. strain ADP was expressed and pu
Autor:
Sahil Balotra, Santosh Panjikar, Colin Scott, Janet Newman, Thomas S. Peat, Matthew Wilding, Nathan Cowieson, Nigel G. French, Lyndall J. Briggs
Publikováno v:
Molecular Microbiology
Summary The cyanuric acid hydrolase, AtzD, is the founding member of a newly identified family of ring-opening amidases. We report the first X-ray structure for this family, which is a novel fold (termed the ‘Toblerone’ fold) that likely evolved
Autor:
Lyndall J. Briggs, Matthew C. Taylor, Robyn J. Russell, Nigel P. French, Colin Scott, Colin J. Jackson, Thomas S. Peat, David B. Tattersall, Janet Newman, John G. Oakeshott, Peter M. Campbell, Gauri V. Lapalikar
Publikováno v:
Molecular Microbiology. 78:561-575
Aflatoxins are polyaromatic mycotoxins that contaminate a range of food crops as a result of fungal growth and contribute to serious health problems in the developing world because of their toxicity and mutagenicity. Although relatively resistant to
Autor:
Lyndall J. Briggs, Thomas S. Peat, Sahil Balotra, Janet Newman, Colin Scott, Andrew C. Warden
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0137700 (2015)
PLoS ONE
PLoS ONE
The N-isopropylammelide isopropylaminohydrolase from Pseudomonas sp. strain ADP, AtzC, provides the third hydrolytic step in the mineralization of s-triazine herbicides, such as atrazine. We obtained the X-ray crystal structure of AtzC at 1.84 Å wit
Autor:
Lyndall J. Briggs, Christopher J. Easton, Sahil Balotra, Thomas S. Peat, Nathan Cowieson, Nigel G. French, Colin Scott, Janet Newman, Andrew C. Warden, Peter M. Campbell
Publikováno v:
Applied and environmental microbiology. 81(2)
The activity of the allophanate hydrolase from Pseudomonas sp. strain ADP, AtzF, provides the final hydrolytic step for the mineralization of s -triazines, such as atrazine and cyanuric acid. Indeed, the action of AtzF provides metabolic access to tw
Autor:
Sophie L. Le Page, Sue M. Firth, Lyndall J. Briggs, Lynette J. Schedlich, Robert C. Baxter, David A. Jans
Publikováno v:
Journal of Biological Chemistry. 275:23462-23470
Although insulin-like growth factor-binding protein (IGFBP)-3 and IGFBP-5 are known to modulate cell growth by reversibly sequestering extracellular insulin-like growth factors, several reports have suggested that IGFBP-3, and possibly also IGFBP-5,
Autor:
Lyndall J. Briggs, Sabine C. Piller, Chong Yun Xiao, Torsten Jülich, David A. Jans, Patricia Jans
Publikováno v:
Biochemical and Biophysical Research Communications. 270:1055-1062
The regulatory protein Vpr of the human immunodeficiency virus HIV-1 performs multiple functions during the HIV replicative cycle. It is involved in the transport of the viral preintegration complex into the nucleus, and has the ability to interact w
Autor:
Sally C. Ford, Ian G. Young, Lyndall J. Briggs, David A. Jans, Patricia Jans, Sonja E. Gustin
Publikováno v:
FEBS Letters. 406:315-320
Interleukin (IL)-5 is central in regulating eosinophilia in allergic disease and parasitic infections. We have identified a bipartite nuclear localisation signal (NLS) within amino acids 95–111 of human IL-5 (hIL-5), also present in mouse IL-5 (mIL
Publikováno v:
Journal of Biological Chemistry. 271:30781-30789
Cytotoxic T and natural killer cells are able to kill their target cells through synergistic action of the pore-forming protein perforin and the serine protease granzyme B, resulting in very distinctive nuclear changes typical of apoptosis. Whereas p