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pro vyhledávání: '"Lynda S. Cook"'
Autor:
Lynda S. Cook
Publikováno v:
Journal of Infusion Nursing. 46:14-27
Autor:
Lynda S, Cook
Publikováno v:
Journal of infusion nursing : the official publication of the Infusion Nurses Society. 46(1)
Hemolysis is a problem associated with a variety of red cell pathologies and physiologies not limited to the transfusion of cells. Various pathways lead to the observed outcomes when a hemolytic event occurs. Each event, and the pathway it follows, i
Autor:
Lynda S, Cook
Publikováno v:
Journal of Infusion Nursing. 39:273-279
Venipuncture is generally associated with some degree of pain, discomfort, and/or apprehension. Yet most patients accept it with tolerance, even nonchalance. A few, not only pediatric patients, exhibit a higher degree of anxiety and face the procedur
Autor:
John Morrison, Kenneth M. Boy, Alan S. Robertson, Malaz AbuTarif, Jeremy H. Toyn, Valerie Guss, Xiaoliang Zhuo, Maciej Gasior, James E. Grace, Cong Wei, Jun-Sheng Wang, Quan Hong, Joseph Raybon, Lynda S. Cook, Nina Hoque, Richard E. Olson, Wendy Clarke, Rex Denton, Lorin A. Thompson, Francis Sweeney, Flora Berisha, Jere E. Meredith, Dieter M. Drexler, Holly Soares, Kimberly A. Lentz, Charlie F. Albright, Ramesh Padmanabha, Michael J. Furlong, John E. Macor, Michael K. Ahlijanian, Dmitry Zuev, Kimberly Snow
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
The amyloid-β peptide (Aβ)-in particular, the 42-amino acid form, Aβ1-42-is thought to play a key role in the pathogenesis of Alzheimer's disease (AD). Thus, several therapeutic modalities aiming to inhibit Aβ synthesis or increase the clearance
Autor:
Lori Van Gosen, Pam Sabatino-Holmes, Lisa A. Gorski, Marc Stranz, Lynda S. Cook, Kathy Kokotis, James M Joseph
Publikováno v:
Journal of infusion nursing : the official publication of the Infusion Nurses Society. 40(1)
Infiltration of a vesicant medication, defined as extravasation, may result in significant patient injuries. The first step in preventing extravasation is the identification and recognition of vesicant medications and solutions. Because there is no l
Autor:
John E. Macor, Ramesh Padmanabha, Jere E. Meredith, Jeremy H. Toyn, William J. Metzler, Andrew J. Tebben, Jodi K. Muckelbauer, Charles F. Albright, Lynda S. Cook, Lorin A. Thompson, Samuel Gerritz, Michael J. Sofia, Michael A. Poss, Shirong Zhu, Lawrence G. Iben, Daniel M. Camac, Kimberley A. Lentz, Shuhao Shi, Andrew C. Good, Weixu Zhai, Catherine R. Burton
Publikováno v:
Journal of Medicinal Chemistry. 55:9208-9223
This report describes the discovery and optimization of a BACE-1 inhibitor series containing an unusual acyl guanidine chemotype that was originally synthesized as part of a 6041-membered solid-phase library. The synthesis of multiple follow-up solid
Autor:
Lynda S. Cook
Publikováno v:
Journal of Infusion Nursing. 33:81-88
In the United States, phlebotomies are most often performed for reinfusion of blood to a designated or nondesignated recipient at a later time. These are known, respectively, as autologous or allogenic donations. For a few rare blood disorders, howev
Autor:
Lynda S. Cook
Publikováno v:
Nursing (Ed. española). 27:26-29
Publikováno v:
Combinatorial Chemistry & High Throughput Screening. 8:521-527
Changes in all aspects of HTS from compound management through to evaluation of hits and leads, strengthened by infrastructure improvements, in both automation and informatics, have made possible increased analysis and implementation of process and q
Autor:
Lynda S. Cook, Laura Zawadzke, Ramesh Padmanabha, Ping Wu, Margaret Casperson, Li Fan, Mona Kishnani, Deepa Calambur, Hofstead Sandra J
Publikováno v:
Analytical Biochemistry. 314:243-252
Assays for two enzymes from Escherichia coli were developed and validated as antibacterial inhibitor screens. The MraY and MurG enzymes were overexpressed and purified as the membrane fraction or to homogeneity, respectively. The MurG enzyme was expr