Výsledky vyhledávání - "Lynda M, Vrooman"

Akademický článek

Venous thromboembolism in adolescents and young adults with acute lymphoblastic leukemia treated on a pediatric-inspired regimen

Publikováno v: Blood Cancer Journal, Vol 14, Iss 1, Pp 1-7 (2024)

Abstract Asparaginase (ASP)-containing regimens for acute lymphoblastic leukemia (ALL) are associated with venous thromboembolism (VTE). We evaluated the prevalence, risk factors, role of prophylaxis and clinical impact of VTE among adolescents and y

Externí odkaz: https://doaj.org/article/722f871ad92a408282748661f0239bc4

Zobrazit plný text záznamu

Dexrazoxane and Long-Term Heart Function in Survivors of Childhood Cancer

Autor: Eric J. Chow, Sanjeev Aggarwal, David R. Doody, Richard Aplenc, Saro H. Armenian, K. Scott Baker, Smita Bhatia, Nancy Blythe, Steven D. Colan, Louis S. Constine, David R. Freyer, Lisa M. Kopp, Caroline Laverdière, Wendy M. Leisenring, Nao Sasaki, Lynda M. Vrooman, Barbara L. Asselin, Cindy L. Schwartz, Steven E. Lipshultz

Publikováno v: Journal of Clinical Oncology. 41:2248-2257

PURPOSE For survivors of childhood cancer treated with doxorubicin, dexrazoxane is cardioprotective for at least 5 years. However, longer-term data are lacking. METHODS Within the Children's Oncology Group and the Dana Farber Cancer Institute's Child

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5aa83f6ba1b34a89ce9210ba895b8667
https://doi.org/10.1200/jco.22.02423

Zobrazit plný text záznamu

Nelarabine combination therapy for relapsed or refractory T-cell acute lymphoblastic lymphoma/leukemia

Autor: Shai Shimony, Yiwen Liu, Yannis K. Valtis, Jonathan D. Paolino, Andrew E. Place, Andrew M. Brunner, Lachelle D. Weeks, Lewis B. Silverman, Lynda M. Vrooman, Donna S. Neuberg, Richard M. Stone, Daniel J. DeAngelo, Marlise R. Luskin

Publikováno v: Blood Advances. 7:1092-1102

Nelarabine, an antimetabolite prodrug, is approved as monotherapy for children and adults with relapsed and refractory T-cell acute lymphoblastic leukemia and lymphoma (R/R T-ALL/LBL), although it is often used in combination regimens. We sought to u

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc095a2bd1732c10f6011777ff627303
https://doi.org/10.1182/bloodadvances.2022008280

Zobrazit plný text záznamu

Akademický článek

Refining risk classification in childhood B acute lymphoblastic leukemia: results of DFCI ALL Consortium Protocol 05-001

Publikováno v: Blood Advances, Vol 2, Iss 12, Pp 1449-1458 (2018)

Abstract: Dana-Farber Cancer Institute (DFCI) ALL Consortium Protocol 05-001 tested a new risk stratification system in children and adolescents with newly diagnosed acute lymphoblastic leukemia (ALL). At study entry, B-ALL patients were classified a

Externí odkaz: https://doaj.org/article/7fe5b025a97248a2bd7140b86b897665

Zobrazit plný text záznamu

Cardiometabolic Risk in Childhood Cancer Survivors: A Report from the Children's Oncology Group

Autor: Cindy L. Schwartz, Steven E. Lipshultz, Emma R. Lipshultz, Lynda M. Vrooman, Eric J. Chow, David R. Doody, Saro H. Armenian, Barbara L. Asselin, Louis S. Constine, David R. Freyer, K. Scott Baker, Lisa M. Kopp, Smita Bhatia

Publikováno v: Cancer Epidemiology, Biomarkers & Prevention. 31:536-542

Background: Childhood cancer survivors are at risk for cardiovascular disease. We assessed the burden of potentially modifiable cardiometabolic risk factors (CRF) among survivors compared with population-matched controls. Methods: Survivors previousl

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f9233e426b18aae299eecf711dc5e0
https://doi.org/10.1158/1055-9965.epi-21-0360

Zobrazit plný text záznamu

Orthopedic toxicities among adolescents and young adults treated in DFCI ALL Consortium Trials

Autor: Daniel J. DeAngelo, Yannis K. Valtis, Lewis B. Silverman, Andrew E. Place, Kristen E. Stevenson, Lynda M. Vrooman, Mary Nauffal, Marlise R. Luskin, Giacomo Gotti, Andrew M. Brunner

Publikováno v: Blood Advances

Key Points Orthopedic toxicity was common in adolescent and young adult patients treated on DFCI Consortium ALL pediatric protocols.Younger age and exposure to pegaspargase were associated with higher risk of ON, and patients with ON had superior OS.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d80654992267ede6e099757930e0554
http://europepmc.org/articles/PMC8753211

Zobrazit plný text záznamu

Late health outcomes after dexrazoxane treatment: A report from the Children's Oncology Group

Autor: Louis S. Constine, Lisa M. Kopp, Smita Bhatia, Cindy L. Schwartz, David R. Freyer, Steven E. Lipshultz, David R. Doody, Richard Aplenc, Lynda M. Vrooman, Saro H. Armenian, K. Scott Baker, Sanjeev Aggarwal, Wendy M. Leisenring, Eric J. Chow, Barbara L. Asselin, Yuan-Shung Huang

Publikováno v: Cancer

Background The objective of this study was to examine long-term outcomes among children newly diagnosed with cancer who were treated in dexrazoxane-containing clinical trials. Methods P9404 (acute lymphoblastic leukemia/lymphoma [ALL]), P9425 and P94

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5008997f9e69602eaac4b8affbb2e959
https://doi.org/10.1002/cncr.33974

Zobrazit plný text záznamu

Predicting chronic morbidity in childhood cancer survivors

Autor: Lynda M, Vrooman, Lisa R, Diller

Publikováno v: Nat Med

Adult survivors of childhood cancer have high rates of obesity, which in combination with the cardiotoxic effects of specific cancer therapies places them at high-risk for cardiovascular morbidity. Here we show the contribution of genetic risk scores

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b225138eace9b0690456c5b9ba950c28
https://pubmed.ncbi.nlm.nih.gov/35879615

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání