Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lynda L. Lanning"'
Autor:
Tina Guina, Lynda L. Lanning, Kristian S. Omland, Mark S. Williams, Larry A. Wolfraim, Stephen P. Heyse, Christopher R. Houchens, Patrick Sanz, Judith A. Hewitt
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Francisella tularensis is a highly infectious Gram-negative bacterium that is the etiologic agent of tularemia in animals and humans and a Tier 1 select agent. The natural incidence of pneumonic tularemia worldwide is very low; therefore, it is not f
Externí odkaz:
https://doaj.org/article/dcbf1003b6114ee2ac83127c33047359
Publikováno v:
Clin Infect Dis
Background Additional treatment options for pneumonic plague, the most severe form of infection by Yersinia pestis, are needed, as past US Food and Drug Administration (FDA) approvals were not based on clinical trials that meet today’s standards, a
Publikováno v:
Clin Infect Dis
BackgroundCiprofloxacin and levofloxacin, 2 fluoroquinolone antimicrobials, are ≥90% effective for the treatment of inhalational plague when administered within 2–6 hours of fever onset in African green monkeys (AGM). Based on data in the AGM mod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::799b82e0c460a6f9cb0129f1597348c4
https://europepmc.org/articles/PMC7240338/
https://europepmc.org/articles/PMC7240338/
Autor:
Beverly Fogtman, Marianne R. Baker, Tina Guina, Mark S. Williams, Lynda L Lanning, Jeanine M. May, Judith A. Hewitt, Phillip R. Pittman, Heather Hill
Publikováno v:
Frontiers in Medicine
Frontiers in Medicine, Vol 6 (2019)
Frontiers in Medicine, Vol 6 (2019)
Francisella tularensis is a highly infectious Gram-negative bacterium that is the etiologic agent of tularemia in animals and humans. The incidence of tularemia is very low with a lack of comprehensive data that describe disease in humans due to diff
Autor:
Haruhiko Murata, Romelda L Omeir, Gideon Foseh, Kathryn Phy, Lynda L Lanning, Keith Peden, Andrew M. Lewis, Wei Tu
Publikováno v:
Vaccine: X, Vol 1, Iss, Pp-(2019)
Vaccine: X
Vaccine: X
Highlights • Tumorigenicity assays can be time-consuming and results can be equivocal. • Basement membrane extract (BME) is known to enhance tumorigenicity. • The tumorigenicity of Vero (≤p258) and ARPE-19 cells were not enhanced by BME. •
Autor:
Patrick Sanz, Kristian Shawn Omland, Christopher R. Houchens, Judith A. Hewitt, Larry A. Wolfraim, Tina Guina, Mark S. Williams, Lynda L Lanning, Stephen P. Heyse
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
Frontiers in Cellular and Infection Microbiology
Frontiers in Cellular and Infection Microbiology
Francisella tularensis is a highly infectious Gram-negative bacterium that is the etiologic agent of tularemia in animals and humans and a Tier 1 select agent. The natural incidence of pneumonic tularemia worldwide is very low; therefore, it is not f
Autor:
Donald G. Blair, Li Sheng-Fowler, Juliete Macauley, Haiqing Fu, Haruhiko Murata, Stephen H. Hughes, Keith Peden, Lynda L Lanning, John M. Coffin, Andrew M. Lewis, Wei Tu, Gideon Foseh
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e108926 (2014)
PLoS ONE
PLoS ONE
As part of safety studies to evaluate the risk of residual cellular DNA in vaccines manufactured in tumorigenic cells, we have been developing in vivo assays to detect and quantify the oncogenic activity of DNA. We generated a plasmid expressing both
Autor:
Gary W. Wolfe, B Collins, J. Delaney, Robert E. Chapin, Barbara J. Davis, Yefan Wang, N. Mintz, Lynda L. Lanning
Publikováno v:
Toxicological Sciences. 52:80-91
The alkylphenol breakdown products of alkylphenol ethoxylates have been shown in in vitro studies to be weakly estrogenic, but few in vivo data address this issue in mammals. Because estrogens have been found to be most potent during developmental/pe
Publikováno v:
Marine pollution bulletin. 51(5-7)
Coral reefs are in crisis. Globally, our reefs are degrading at an accelerating rate and present methodologies for coral-reef health assessment, although providing important information in describing these global declines, have been unable to halt th
Autor:
Dianne M. Creasy, J. Mark Cline, Kenneth E. Stebbins, Barbara J. Davis, Sabine Rehm, John R. Latendresse, Karen S. Regan, George L. Foley, Daniel Morton, Lynda L. Lanning, Susan L. Makris
Publikováno v:
Toxicologic pathology. 33(3)
Evaluation of the ovary is an important endpoint in tox-icological assessments because xenobiotics that cause lossof oogonia, oocytes, or supportive somatic cells may haveadverse effects on reproduction. To make an adequate histo-logic assessment of