Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Lynda K. Doolittle"'
Autor:
Maximilian W. G. Schneider, Bryan A. Gibson, Shotaro Otsuka, Maximilian F. D. Spicer, Mina Petrovic, Claudia Blaukopf, Christoph C. H. Langer, Paul Batty, Thejaswi Nagaraju, Lynda K. Doolittle, Michael K. Rosen, Daniel W. Gerlich
Publikováno v:
Nature. 609:183-190
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells1–3. Assembly of mitotic chromosomes involves DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0cac9a3afd221a83f2f882c4ac550a
https://doi.org/10.1038/s41586-022-05027-y
https://doi.org/10.1038/s41586-022-05027-y
Autor:
Bryan A. Gibson, Claudia Blaukopf, Tracy Lou, Lifeng Chen, Lynda K. Doolittle, Ilya Finkelstein, Geeta J. Narlikar, Daniel W. Gerlich, Michael K. Rosen
Publikováno v:
Proceedings of the National Academy of Sciences. 120
Nuclear DNA in eukaryotes is wrapped around histone proteins to form nucleosomes on a chromatin fiber. Dynamic folding of the chromatin fiber into loops and variations in the degree of chromatin compaction regulate essential processes such as transcr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f804351a21fc7e38a96f62864b8c10e
https://doi.org/10.1073/pnas.2218085120
https://doi.org/10.1073/pnas.2218085120
Autor:
Baoyu Chen, Hui-Ting Chou, Chad A Brautigam, Wenmin Xing, Sheng Yang, Lisa Henry, Lynda K Doolittle, Thomas Walz, Michael K Rosen
Publikováno v:
eLife, Vol 6 (2017)
The Rho GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3 complex-mediated actin polymerization, which underpins diverse cellular processes. Here we report the structure of a WRC-Rac1 complex determined by cryo-electron microsco
Externí odkaz:
https://doaj.org/article/d8f2a102fa8b48d786f9e435625e56f9
Autor:
Daniel W. Gerlich, Michael K. Rosen, Geeta J. Narlikar, Ilya J. Finkelstein, Bryan A. Gibson, T. Lou, Claudia Blaukopf, Lynda K. Doolittle
SUMMARYEukaryotic nuclear DNA is wrapped around histone proteins to form nucleosomes, which further assemble to package and regulate the genome. Understanding of the physical mechanisms that contribute to higher order chromatin organization is limite
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::021448408550dac3ef0101a2c117969c
https://doi.org/10.1101/2021.11.22.469620
https://doi.org/10.1101/2021.11.22.469620
Autor:
Bryan A. Gibson, Daniel W. Gerlich, Michael K. Rosen, Maximilian W. G. Schneider, Christoph C. H. Langer, Lynda K. Doolittle, Mina Petrovic, Shotaro Otsuka, Maximilian F.D. Spicer, Claudia Blaukopf
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells1–3. Assembly of mitotic chromosomes involves DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::491fade5aec918161d2a56470344d8a4
https://doi.org/10.1101/2021.07.05.450834
https://doi.org/10.1101/2021.07.05.450834
Autor:
Maximilian W G, Schneider, Bryan A, Gibson, Shotaro, Otsuka, Maximilian F D, Spicer, Mina, Petrovic, Claudia, Blaukopf, Christoph C H, Langer, Paul, Batty, Thejaswi, Nagaraju, Lynda K, Doolittle, Michael K, Rosen, Daniel W, Gerlich
Publikováno v:
Nature. 609(7925)
Dividing eukaryotic cells package extremely long chromosomal DNA molecules into discrete bodies to enable microtubule-mediated transport of one genome copy to each of the newly forming daughter cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0dde7764f9363659e3b996d73e55d7b9
https://pubmed.ncbi.nlm.nih.gov/35922488
https://pubmed.ncbi.nlm.nih.gov/35922488
Autor:
Benjamin A Smith, Shae B Padrick, Lynda K Doolittle, Karen Daugherty-Clarke, Ivan R Corrêa Jr, Ming-Qun Xu, Bruce L Goode, Michael K Rosen, Jeff Gelles
Publikováno v:
eLife, Vol 2 (2013)
During cell locomotion and endocytosis, membrane-tethered WASP proteins stimulate actin filament nucleation by the Arp2/3 complex. This process generates highly branched arrays of filaments that grow toward the membrane to which they are tethered, a
Externí odkaz:
https://doaj.org/article/101ba6f4735146f682e1059f11779d6f
Autor:
Michael K. Rosen, Lynda K. Doolittle, Bryan A. Gibson, Sy Redding, Liv E. Jensen, Daniel W. Gerlich, Lisa Henry, Maximillian W.G. Schneider, Nathan Gamarra
Publikováno v:
Cell
Eukaryotic chromatin is highly condensed but dynamically accessible to regulation and organized into subdomains. We demonstrate that reconstituted chromatin undergoes histone tail-driven liquid-liquid phase separation (LLPS) in physiologic salt and w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ba876d7d5c77afa0882f8cc9ac332d9
https://pubmed.ncbi.nlm.nih.gov/31543265
https://pubmed.ncbi.nlm.nih.gov/31543265
Autor:
Lynda K. Doolittle, Bryan A. Gibson, Liv E. Jensen, Michael K. Rosen, Nathan Gamarra, Sy Redding
Genomic DNA is highly compacted in the nucleus of eukaryotic cells as a nucleoprotein assembly called chromatin1. The basic unit of chromatin is the nucleosome, where ∼146 base pair increments of the genome are wrapped and compacted around the core
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3bf4f1b862ecfd7a777a36acece108
Autor:
Hui-Ting Chou, Sheng Yang, Thomas Walz, Lynda K. Doolittle, Chad A. Brautigam, Baoyu Chen, Wenmin Xing, Michael K. Rosen, Lisa Henry
Publikováno v:
eLife
eLife, Vol 6 (2017)
eLife, Vol 6 (2017)
The Rho GTPase Rac1 activates the WAVE regulatory complex (WRC) to drive Arp2/3 complex-mediated actin polymerization, which underpins diverse cellular processes. Here we report the structure of a WRC-Rac1 complex determined by cryo-electron microsco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e3d767a24da3a3ab0c44dde6340b84d
http://europepmc.org/articles/PMC5614565
http://europepmc.org/articles/PMC5614565