Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Lynda Erskine"'
Publikováno v:
Stem Cell Research, Vol 33, Iss , Pp 185-198 (2018)
Limbal epithelial stem cells (LESCs) are believed to be responsible for corneal epithelial maintenance and repair after injury, but their activity has never been properly quantified in aging or wounded eyes. In this study, labelling with thymidine an
Externí odkaz:
https://doaj.org/article/6a4864883f7a428f9ff70d11d20d565b
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3282 (2019)
Retinal ganglion cells (RGCs) extend axons out of the retina to transmit visual information to the brain. These connections are established during development through the navigation of RGC axons along a relatively long, stereotypical pathway. RGC axo
Externí odkaz:
https://doaj.org/article/78733fc25c62473984ccec479058e391
Autor:
Lynda Erskine, Eloisa Herrera
Publikováno v:
ASN Neuro, Vol 6 (2014)
The visual system is beautifully crafted to transmit information of the external world to visual processing and cognitive centers in the brain. For visual information to be relayed to the brain, a series of axon pathfinding events must take place to
Externí odkaz:
https://doaj.org/article/20d05e4e9f1b483499264cb52e88bc4d
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
In order to navigate through the surrounding environment many mammals, including humans, primarily rely on vision. The eye, composed of the choroid, sclera, retinal pigmented epithelium, cornea, lens, iris and retina, is the structure that receives t
Publikováno v:
Developmental Dynamics. 247:1217-1226
The authors declare no conflicts of interest. The authors thank Yolanda Ramirez Casas and J. Martin Collinson for technical advice and past and present lab staff for helpful discussions.
Publikováno v:
Developmental dynamics : an official publication of the American Association of AnatomistsREFERENCES. 250(9)
Background Slits (1-3) and their Robo (1-3) receptors play multiple non-neuronal roles in development, including in development of muscle, heart and mammary gland. Previous work has demonstrated expression of Slit and Robo family members during limb
Autor:
Miguel Tillo, Urielle François, Laura Denti, Neil Vargesson, Freyja Bruce, Christiana Ruhrberg, Andy Joyce, Lynda Erskine
Publikováno v:
BASE-Bielefeld Academic Search Engine
Development (Cambridge, England)
Development (Cambridge, England)
Visual information is relayed from the eye to the brain via retinal ganglion cell (RGC) axons. Mice lacking NRP1 or NRP1-binding VEGF-A isoforms have defective RGC axon organisation alongside brain vascular defects. It is not known whether axonal def
Autor:
J. Martin Collinson, Hannah Thompson, Heather M. Walker, Jonathan N Smith, Neil Vargesson, Lynda Erskine
Publikováno v:
Development (Cambridge, England). 145(19)
Absence of the developing lens results in severe eye defects, including substantial reductions in eye size. How the lens controls eye expansion and the underlying signalling pathways are very poorly defined. We identified RDH10, a gene crucial for re
Autor:
Yaiza Coca, Luis M. Martinez, Ronan DaSilva, Artur Kania, Víctor Borrell, Santiago Negueruela, Lynda Erskine, Arturo José Valiño, Eloisa Herrera, Celia Vegar, Verónica Murcia-Belmonte, Salvador Sala, Camino de Juan
Publikováno v:
SSRN Electronic Journal.
The existence of axons extending from one retina to the other has been reported during perinatal development in different vertebrates. However, it has been thought that these axons are either a labelling artefact or misprojections. Here, we unequivoc
Autor:
Alexandra J Rafipay, William D. Figg, Lucas Rosa Fraga, Michael Gütschow, Christopher B. Mahony, Scott McMenemy, Neil Vargesson, Lynda Erskine, Shaunna-Leigh Beedie
Thalidomide notoriously caused severe birth defects, particularly to the limbs, in those exposed in utero following maternal use of the drug to treat morning sickness. How the drug caused these birth defects remains unclear. Many theories have been p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8abeae8537f6cf54532a86066f07ab44
https://europepmc.org/articles/PMC5835787/
https://europepmc.org/articles/PMC5835787/