Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Lynda Bennett"'
Autor:
Stephen X. Skapek, Yanbin Zheng, Priscilla Liem, Qinbo Zhou, Jing Liu, Jared C. Hooks, Lynda Bennett, Lin Xu, Yen-Ting Liu
Disruption of the CDKN2A (INK4A/ARF) and B (INK4B) genes, which encode three function-independent tumor suppressors, is one of the most common events in human cancer. Because their relative importance in tumor prevention appears to be species- and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdacb882248483cb660a5ce1f2ea3454
https://doi.org/10.1158/1541-7786.c.6540370
https://doi.org/10.1158/1541-7786.c.6540370
Autor:
Stephen X. Skapek, Yanbin Zheng, Priscilla Liem, Qinbo Zhou, Jing Liu, Jared C. Hooks, Lynda Bennett, Lin Xu, Yen-Ting Liu
Supplementary Table S1. Sequences of siRNAs, sgRNAs and primers for regular PCR, qRT-PCR and ChIP-qPCR Figure S1. Global analysis of ARF regulation from The Cancer Genome Atlas (TCGA). Figure S2. The status of DNA methylation at promoter regions of C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15abb094d51e6a185b5fbcd3ea41b526
https://doi.org/10.1158/1541-7786.22512907.v1
https://doi.org/10.1158/1541-7786.22512907.v1
Publikováno v:
Cancer Research. 83:654-654
Elevated levels of immunosuppressive myeloid-derived suppressor cells (MDSCs) circulate in the peripheral blood or infiltrate the tumors as well as ascites in ovarian cancer patients, however the cause for this observed phenotype is unknown. MDSCs co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8771edcccb1dcb92f79ffe451e44788
https://doi.org/10.1158/1538-7445.am2023-654
https://doi.org/10.1158/1538-7445.am2023-654
Publikováno v:
Cancer Research. 83:3697-3697
Introduction: Cancer cells often develop a program of metabolic adaptability and epigenetic remodelling to promote gene expression changes causing cancerous cell proliferation and invasion. The metabolic-epigenetic axis as a an underlying mechanism o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d83c65bf77e87744e6355926621b4861
https://doi.org/10.1158/1538-7445.am2023-3697
https://doi.org/10.1158/1538-7445.am2023-3697
Autor:
Jared C. Hooks, Yanbin Zheng, Yen Ting Liu, Jing Liu, Lin Xu, Priscilla Liem, Stephen X. Skapek, Lynda Bennett, Qinbo Zhou
Publikováno v:
Molecular Cancer Research. 17:1854-1866
Disruption of the CDKN2A (INK4A/ARF) and B (INK4B) genes, which encode three function-independent tumor suppressors, is one of the most common events in human cancer. Because their relative importance in tumor prevention appears to be species- and co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87df8aa8aa53c4222fce40caf955ddff
https://doi.org/10.1158/1541-7786.mcr-19-0289
https://doi.org/10.1158/1541-7786.mcr-19-0289
Autor:
Candace Frerich, Ishrat Durdana, Ariella Hanker, Carlos L. Arteaga, Lynda Bennett, Suzanne Conzen
Publikováno v:
Cancer Research. 82:2699-2699
While considered uncommon, there are an estimated 39,000 new invasive lobular carcinoma (ILC) cases in the US yearly, making it the sixth most common among all tumor types. ILC is recognized for unique metastatic organotropism. Its propensity to meta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3278c589a668e23391ff3471d97873e9
https://doi.org/10.1158/1538-7445.am2022-2699
https://doi.org/10.1158/1538-7445.am2022-2699
Publikováno v:
Cancer Research. 82:1335-1335
Immunosuppressive cells abundantly infiltrate tumors during cancer progression. Notably, immunosuppressive myeloid-derived suppressor cells (MDSCs) have recently been identified as a heterogeneous cell population that expand during tumor-associated i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::718699841fbcb1e9252901ab2a0397ea
https://doi.org/10.1158/1538-7445.am2022-1335
https://doi.org/10.1158/1538-7445.am2022-1335
Autor:
Tobias Wijshake, Beth Levine, John G. Doench, Yang Xie, Guanghua Xiao, Beibei Chen, Lynda Bennett, Lin Zhong, Zhongju Zou
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Beclin 1, an essential autophagy protein, is important for tumor suppression in mice, as well as in human breast and ovarian cancers. However, it is not well understood how Beclin 1 acts as a tumor suppressor. By performing a genetic scr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::917ad133de3e5454e51f4b362984a625
https://pubmed.ncbi.nlm.nih.gov/33495338
https://pubmed.ncbi.nlm.nih.gov/33495338
Publikováno v:
The Journal of Immunology. 208:178.10-178.10
Myeloid-derived suppressor cells (MDSCs) have been identified as a heterogeneous cell population that expand during tumor progression and infiltrate the tumor, peripheral blood, as well as ascites of ovarian cancer patients. MDSCs contribute to tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40fe3a5ca2883f83deecde266faf529d
https://doi.org/10.4049/jimmunol.208.supp.178.10
https://doi.org/10.4049/jimmunol.208.supp.178.10
Autor:
Sangita C. Sinha, Beth Levine, Zhongju Zou, Li Yu, Yue Li, Lynda Bennett, Y. Zhao, Daxiao Sun
Publikováno v:
Autophagy
article-version (VoR) Version of Record
article-version (VoR) Version of Record
A key mediator of macroautophagy/autophagy induction is the class III phosphatidylinositol 3-kinase complex I (PtdIns3K-C1) consisting of PIK3C3/VPS34, PIK3R4/VPS15, BECN1, and ATG14. Although several proteins are known to enhance or decrease PtdIns3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c9c22d2df31315b28f4d1005bd9d948
https://pubmed.ncbi.nlm.nih.gov/33222586
https://pubmed.ncbi.nlm.nih.gov/33222586