Zobrazeno 1 - 10
of 169
pro vyhledávání: '"Lynch-like syndrome"'
Autor:
Wen-Xuan Fan, Fei Su, Yan Zhang, Xiao-Ling Zhang, Yun-Yi Du, Yang-Jun Gao, Wei-Ling Li, Wen-Qing Hu, Jun Zhao
Publikováno v:
Biomarker Research, Vol 12, Iss 1, Pp 1-14 (2024)
Abstract Colorectal cancer (CRC) ranks as the third most prevalent cancer globally. It’s recognized that the molecular subtype of CRC, characterized by mismatch repair deficiency (dMMR) or microsatellite instability-high (MSI-H), plays a critical r
Externí odkaz:
https://doaj.org/article/5ee19264a2854a77919b87c77cbadd29
Autor:
Tiansong Zhang, Xiaoqiang Huang, Wenjie Liu, Xiulan Ling, Zhenping Su, Mengwei Huang, Shuanlong Che
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-8 (2024)
Abstract Background Multiple primary malignancies are rare in cancer patients, and risk factors may include genetics, viral infection, smoking, radiation, and other environmental factors. Lynch syndrome (LS) is the most prevalent form of hereditary p
Externí odkaz:
https://doaj.org/article/534f5e82f93f4ec5b034a2ea200c8f07
Autor:
Paula Rofes, Núria Dueñas, Jesús delValle, Matilde Navarro, Judith Balmaña, Teresa Ramón y Cajal, Noemí Tuset, Carmen Castillo, Sara González, Joan Brunet, Gabriel Capellá, Conxi Lázaro, Marta Pineda
Publikováno v:
Cancer Medicine, Vol 13, Iss 7, Pp n/a-n/a (2024)
Abstract Background Up to 70% of suspected Lynch syndrome patients harboring MMR deficient tumors lack identifiable germline pathogenic variants in MMR genes, being referred to as Lynch‐like syndrome (LLS). Previous studies have reported biallelic
Externí odkaz:
https://doaj.org/article/89ec02fadf8b49ddb36b4954ab5c79ac
Autor:
Zornitsa Bogomilova Kamburova, Polina Damyanova Dimitrova, Diana Strateva Dimitrova, Katya Stefanova Kovacheva, Savelina Lubenova Popovska, Slavena Enkova Nikolova
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 21, Iss 1, Pp 1-8 (2023)
Abstract Background Synchronous endometrial and ovarian cancer (SEOC) accounts for 50–70% of all synchronous gynecology cancers in women. Approximately 14% of SEOC cases are caused by Lynch syndrome (LS). The widespread introduction of “universal
Externí odkaz:
https://doaj.org/article/e2fc24d7fb0f4ad484fba9041fad1faa
Akademický článek
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Autor:
Sowmya Jonnagadla, Sharelle L. Joseland, Sibel Saya, Nicole den Elzen, Joanne Isbister, Ingrid M. Winship, Daniel D. Buchanan
Publikováno v:
Hereditary Cancer in Clinical Practice, Vol 20, Iss 1, Pp 1-11 (2022)
Abstract Background A suspected Lynch syndrome (SLS) diagnosis is made when a tumor exhibits DNA mismatch repair deficiency but cannot be definitively assigned to an inherited or non-inherited etiology. This diagnosis poses challenges for healthcare
Externí odkaz:
https://doaj.org/article/d865cc6207444ab1a3a498c7336b9a40
Autor:
Karolin Bucksch, Silke Zachariae, Stefan Aretz, Reinhard Büttner, Elke Holinski-Feder, Stefanie Holzapfel, Robert Hüneburg, Matthias Kloor, Magnus von Knebel Doeberitz, Monika Morak, Gabriela Möslein, Jacob Nattermann, Claudia Perne, Nils Rahner, Wolff Schmiegel, Karsten Schulmann, Verena Steinke-Lange, Christian P. Strassburg, Deepak B. Vangala, Jürgen Weitz, Markus Loeffler, Christoph Engel, on behalf of the German Consortium for Familial Intestinal Cancer
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-11 (2020)
Abstract Background Individuals with pathogenic germline variants in DNA mismatch repair (MMR) genes are at increased risk of developing colorectal, endometrial and other cancers (Lynch syndrome, LS). While previous studies have extensively described
Externí odkaz:
https://doaj.org/article/7a79a4124bf24cb6aed667604ef06d07
Autor:
Bucksch, Karolin, Zachariae, Silke, Ahadova, Aysel, Aretz, Stefan, Büttner, Reinhard, Görgens, Heike, Holinski-Feder, Elke, Hüneburg, Robert, Kloor, Matthias, von Knebel Doeberitz, Magnus, Ladigan-Badura, Swetlana, Moeslein, Gabriela, Morak, Monika, Nattermann, Jacob, Nguyen, Huu Phuc, Perne, Claudia, Redler, Silke, Schmetz, Ariane, Steinke-Lange, Verena, Surowy, Harald, Vangala, Deepak B., Weitz, Jürgen, Loeffler, Markus, Engel, Christoph, for Familial Intestinal Cancer, German Consortium
Lynch syndrome (LS), Lynch-like syndrome (LLS) and familial colorectal cancer type X (FCCX) are different entities of familial cancer predisposition leading to an increased risk of colorectal cancer (CRC). The aim of this prospective study was to cha
Externí odkaz:
https://ul.qucosa.de/id/qucosa%3A85764
https://ul.qucosa.de/api/qucosa%3A85764/attachment/ATT-0/
https://ul.qucosa.de/api/qucosa%3A85764/attachment/ATT-0/
Akademický článek
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Akademický článek
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