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Radiolabelling and preclinical characterisation of [ ⁸⁹ Zr]Zr-Df-ATG-101 bispecific to PD-L1/4-1BB.

Autor: Cao Z; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia., Wichmann CW; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia.; School of Chemistry - Bio21 Institute, University of Melbourne, Melbourne, Australia., Burvenich IJG; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia., Osellame LD; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia., Guo N; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., Rigopoulos A; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia., O'Keefe GJ; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia.; Department of Medicine, University of Melbourne, Melbourne, Australia., Scott FE; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia.; School of Cancer Medicine, La Trobe University, Melbourne, Australia., Lorensuhewa N; Antengene Biologics Limited, Shanghai, China., Lynch KP; Antengene Biologics Limited, Shanghai, China., Scott AM; Tumour Targeting Laboratory, Olivia Newton-John Cancer Research Institute, Melbourne, Australia. Andrew.Scott@onjcri.org.au.; School of Cancer Medicine, La Trobe University, Melbourne, Australia. Andrew.Scott@onjcri.org.au.; Department of Molecular Imaging and Therapy, Austin Health, Melbourne, Australia. Andrew.Scott@onjcri.org.au.; Department of Medicine, University of Melbourne, Melbourne, Australia. Andrew.Scott@onjcri.org.au.

Publikováno v: European journal of nuclear medicine and molecular imaging [Eur J Nucl Med Mol Imaging] 2024 Sep; Vol. 51 (11), pp. 3202-3214. Date of Electronic Publication: 2024 May 11.