The History of Chromosomal Instability in Genome-Doubled Tumors.

Autor: Baker TM; The Francis Crick Institute, London, United Kingdom.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Medicine, University of California Los Angeles, Los Angeles, California., Lai S; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lynch AR; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Lesluyes T; The Francis Crick Institute, London, United Kingdom., Yan H; The Francis Crick Institute, London, United Kingdom.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Ogilvie HA; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas., Verfaillie A; The Francis Crick Institute, London, United Kingdom., Dentro S; Division of AI in Oncology, German Cancer Research Centre DKFZ, Heidelberg, Germany., Bowes AL; The Francis Crick Institute, London, United Kingdom., Pillay N; Research Department of Pathology, Cancer Institute, University College London, London, United Kingdom.; Department of Cellular and Molecular Pathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, United Kingdom., Flanagan AM; Research Department of Pathology, Cancer Institute, University College London, London, United Kingdom.; Department of Cellular and Molecular Pathology, Royal National Orthopaedic Hospital NHS Trust, Stanmore, United Kingdom., Swanton C; The Francis Crick Institute, London, United Kingdom.; Cancer Research UK Lung Cancer Centre of Excellence, University College London Cancer Institute, London, United Kingdom.; Department of Oncology, University College London Hospitals, London, United Kingdom., Spellman PT; Department of Medicine, University of California Los Angeles, Los Angeles, California., Tarabichi M; The Francis Crick Institute, London, United Kingdom.; Institute for Interdisciplinary Research (IRIBHM), Université Libre de Bruxelles, Brussels, Belgium., Van Loo P; The Francis Crick Institute, London, United Kingdom.; Department of Genetics, The University of Texas MD Anderson Cancer Center, Houston, Texas.; Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.

Publikováno v: Cancer discovery [Cancer Discov] 2024 Oct 04; Vol. 14 (10), pp. 1810-1822.

Diverse microtubule-targeted anticancer agents kill cells by inducing chromosome missegregation on multipolar spindles.

Autor: Zhou AS; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Tucker JB; Cancer Biology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Scribano CM; Molecular and Cellular Pharmacology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Lynch AR; Cellular and Molecular Pathology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Carlsen CL; Cellular and Molecular Biology Graduate Training Program, University of Wisconsin, Madison, Wisconsin, United States of America., Pop-Vicas ST; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America., Pattaswamy SM; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America., Burkard ME; Department of Medicine, University of Wisconsin, Madison, Wisconsin, United States of America.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America.; Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America., Weaver BA; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, Wisconsin, United States of America.; Department of Oncology/McArdle Laboratory for Cancer Research, University of Wisconsin, Madison, Wisconsin, United States of America.; Carbone Cancer Center, University of Wisconsin, Madison, Wisconsin, United States of America.

Publikováno v: PLoS biology [PLoS Biol] 2023 Oct 26; Vol. 21 (10), pp. e3002339. Date of Electronic Publication: 2023 Oct 26 (Print Publication: 2023).

Quantifying chromosomal instability from intratumoral karyotype diversity using agent-based modeling and Bayesian inference.

Autor: Lynch AR; Carbone Cancer Center, University of Wisconsin-Madison, Madison, United States.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, United States., Arp NL; Carbone Cancer Center, University of Wisconsin-Madison, Madison, United States., Zhou AS; Carbone Cancer Center, University of Wisconsin-Madison, Madison, United States.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, United States., Weaver BA; Carbone Cancer Center, University of Wisconsin-Madison, Madison, United States.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, United States.; Department of Cell and Regenerative Biology, University of Wisconsin, Madison, United States., Burkard ME; Carbone Cancer Center, University of Wisconsin-Madison, Madison, United States.; McArdle Laboratory for Cancer Research, University of Wisconsin-Madison, Madison, United States.; Division of Hematology Medical Oncology and Palliative Care, Department of Medicine University of Wisconsin, Madison, United States.

Publikováno v: ELife [Elife] 2022 Apr 05; Vol. 11. Date of Electronic Publication: 2022 Apr 05.

Low-pass whole genome sequencing of circulating tumor cells to evaluate chromosomal instability in triple-negative breast cancer.

Autor: Di Cosimo, Serena¹, Silvestri, Marco^1,2 marco.silvestri@istitutotumori.mi.it, De Marco, Cinzia¹, Calzoni, Alessia^2,3, De Santis, Maria Carmen^4,5, Carnevale, Maria Grazia^4,5, Reduzzi, Carolina⁶, Cristofanilli, Massimo⁶, Cappelletti, Vera¹

Publikováno v: Scientific Reports. 9/3/2024, Vol. 14 Issue 1, p1-8. 8p.

Culturally Relevant Palliative and End-of-Life Care for U.S. Indigenous Populations: An Integrative Review.

Autor: Isaacson MJ; 1 South Dakota State University, Sioux Falls, SD, USA., Lynch AR; 2 Independent researcher, Iowa City, IA, USA.

Publikováno v: Journal of transcultural nursing : official journal of the Transcultural Nursing Society [J Transcult Nurs] 2018 Mar; Vol. 29 (2), pp. 180-191. Date of Electronic Publication: 2017 Jul 22.