Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lyn Wancket"'
Publikováno v:
The Journal of Immunology. 190:138.5-138.5
Although the MKP family plays an important role during host defense, the regulation of MKPs is poorly understood. We studied the expression of MKP-1 and MKP-2 in RAW264.7 cells during LPS stimulation. We found that pretreatment of cells with U0126 (a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::668176369d040017287b84af86d46e63
https://doi.org/10.4049/jimmunol.190.supp.138.5
https://doi.org/10.4049/jimmunol.190.supp.138.5
Autor:
Yusen Liu, Ranyia Matta, John Barnard, Lyn Wancket, Jing Yan, Jessica Grieves, W. Joshua Frazier, Leif Nelin, Andrew Cato
Publikováno v:
The Journal of Immunology. 188:120.21-120.21
Il-10-/- mice develop colitis associated with exaggerated Th1/Th17 responses. Mkp-1 is a negative regulator of MAPKs, and its expression is enhanced by IL-10. To understand the role of Mkp-1 in the regulation of mucosal immune responses, we studied t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::df5fcdee2fc2efeb0c61c3ea8db011bb
https://doi.org/10.4049/jimmunol.188.supp.120.21
https://doi.org/10.4049/jimmunol.188.supp.120.21
Autor:
Yusen Liu, Jing Yan, Xiaomei Meng, Lyn Wancket, Katherine Lintner, Leif Nelin, Bernadette Chen, Kevin Francis, Charles Smith, Lynette Rogers
Publikováno v:
The Journal of Immunology. 188:172.3-172.3
Glutathione reductase (Gsr) catalyzes the reduction of glutathione disulfide to glutathione. Since Gsr has been implicated in the oxidative burst in human PMN, we hypothesized that Gsr-null mice would exhibit marked defects during the immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5c6294236d141be120c70a4419aba11d
https://doi.org/10.4049/jimmunol.188.supp.172.3
https://doi.org/10.4049/jimmunol.188.supp.172.3
Autor:
Jing Yan, Xiaomei Meng, Lyn Wancket, Katherine Lintner, Haiwa Wu, Leif Nelin, Bernadatte Chen, Charles Smith, Lynette Rogers, Yusen Liu
Publikováno v:
The Journal of Immunology. 186:111.25-111.25
Glutathione reductase (Gsr) is an enzyme that reduces glutathione disulfide to the sulfhydryl form, a major cellular antioxidant. Oxidative burst plays an important role in pathogen killing and initiation of inflammation. Proper redox regulation is c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fd94e552dd7e3ec3395e1f7b073f996a
https://doi.org/10.4049/jimmunol.186.supp.111.25
https://doi.org/10.4049/jimmunol.186.supp.111.25
Publikováno v:
The Journal of Immunology. 184:42.4-42.4
MKP-1 is a critical negative regulator of p38 and JNK MAP kinases. While loss of Mkp-1 function enhances cytokine production after bacterial challenge, little is known about the role of Mkp-1 in the innate immune response to viral infections. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ae245b167b5f04b2187cf06cebacf24
https://doi.org/10.4049/jimmunol.184.supp.42.4
https://doi.org/10.4049/jimmunol.184.supp.42.4
Publikováno v:
The Journal of Immunology. 184:47.7-47.7
IBD is a chronic intestinal inflammatory disease that often has extra-intestinal manifestations. We examined the role of the MAPK phosphatase Mkp-1 in a mouse model of IBD. Mkp-1+/+/Il-10+/+, Mkp-1-/-/Il-10+/+, Mkp-1+/+/Il-10-/-, and Mkp-1-/-/Il-10-/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b11639edfad2eeeb70cbf37e81514792
https://doi.org/10.4049/jimmunol.184.supp.47.7
https://doi.org/10.4049/jimmunol.184.supp.47.7