Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Lyn Powell–Braxton"'
Autor:
Timothy J. Lyons, Leslie Eldridge, Mimi Sohn, Lyn Powell-Braxton, Samar M. Hammad, Debra J. Hazen-Martin, Wesley Won
Publikováno v:
Kidney and Blood Pressure Research. 26:351-361
Background/Aims: The contribution of preexisting hypercholesterolemia to diabetic nephropathy remains unclear. We assessed the impact of hypercholesterolemia on diabetic nephropathy using a double knockout (DKO) mouse, null for the low-density lipopr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf123d70739f42849bedd08cab95095
https://doi.org/10.1159/000073942
https://doi.org/10.1159/000073942
Autor:
Jed Ross, Mary E. Gerritsen, Graham F. Wagner, Dorothy French, Stuart Bunting, Renee Eckert, Constance H. Zlot, Richard A.D. Carano, Hope Steinmetz, Ellen Filvaroff, John Hoeffel, Susan Guillet, Gladys Ingle, Lyn Powell-Braxton, Min Bao
Publikováno v:
Endocrinology. 143:3681-3690
Fish stanniocalcin (STC) inhibits uptake of calcium and stimulates phosphate reabsorption. To determine the role of the highly homologous mammalian protein, STC-1, we created and characterized transgenic mice that express STC-1 under control of a mus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70c005152fbf098ff69407294a8380f3
https://doi.org/10.1210/en.2001-211424
https://doi.org/10.1210/en.2001-211424
Autor:
Colin Leary, Bernard P. Halloran, Lyn Powell-Braxton, Clifford J. Rosen, Sharmila Majumdar, Andres Laib, Wesley G. Beamer, Daniel D. Bikle, Eric A. Nauman
Publikováno v:
Journal of Bone and Mineral Research. 16:2320-2329
The importance of insulin-like growth factor I (IGF-I) for growth is well established. However, the lack of IGF-I on the skeleton has not been examined thoroughly. Therefore, we analyzed the structural properties of bone from mice rendered IGF-I defi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::792c216f03e50258ebad5ec7cca70ffd
https://doi.org/10.1359/jbmr.2001.16.12.2320
https://doi.org/10.1359/jbmr.2001.16.12.2320
Publikováno v:
Endocrinology. 140:3881-3889
Pituitary is influenced by circulating and locally produced insulinlike growth factor I (IGF-I). To further elucidate the role of pituitary IGF-I, we compared pituitary morphology of homozygous (IgfI 2/2 ), heterozygous (IgfI 1/2 ), and wild-type (Ig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df566d09fda84a4681593b00f147278
https://doi.org/10.1210/endo.140.9.6973
https://doi.org/10.1210/endo.140.9.6973
Autor:
Natasha Shinsky, Lyn Powell-Braxton, Kathleen A. Elias, Wei-Qiang Gao, Gladys Ingle, Klaus D. Beck
Publikováno v:
Journal of Neurobiology. 39:142-152
Although insulin-like growth factor-I (IGF-I) can act as a neurotrophic factor for peripheral neurons in vitro and in vivo following injury, the role IGF-I plays during normal development and functioning of the peripheral nervous system is unclear. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::967f2221357c00358d7e5f027a740d6d
https://doi.org/10.1002/(sici)1097-4695(199904)39:1<142::aid-neu11>3.0.co
https://doi.org/10.1002/(sici)1097-4695(199904)39:1<142::aid-neu11>3.0.co
Publikováno v:
Developmental Genetics. 24:293-298
Blocking the action of insulin-like growth factor I (IGF I) impairs kidney development in vitro. However, no renal developmental abnormalities have been reported in newborn transgenic mice that do not express IGF I (Igf1−/−) mice. Ninety-five per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3edde16bf96fb73b5a8b86dec38e5855
https://doi.org/10.1002/(sici)1520-6408(1999)24:3/4<293::aid-dvg12>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1999)24:3/4<293::aid-dvg12>3.0.co
Autor:
Wesley Won, Lyn Powell-Braxton, Richard D. Latvala, Stephen G. Young, Murielle M. Véniant, Nicholas O. Davidson, Constance H. Zlot, Noel Dybdal, Ken-Ichi Hirano, Jed Ross
Publikováno v:
Nature Medicine. 4:934-938
Mutations in the low density lipoprotein (LDL) receptor gene cause familial hypercholesterolemia, a human disease characterized by premature atherosclerosis and markedly elevated plasma levels of LDL cholesterol and apolipoprotein (apo) B100. In cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269aacc40542c19b47c3b56ec017e58d
https://doi.org/10.1038/nm0898-934
https://doi.org/10.1038/nm0898-934
Autor:
Napoleone Ferrara, Helen Hsifei Chen, Mark W. Moore, Lyn Powell-Braxton, Karen Carver-Moore, Lucy Lu, Kenneth J. Hillan, Mary Dowd, K. Sue O'Shea
Publikováno v:
Nature. 380:439-442
ANGIOGENESIS is required for a wide variety of physiological and pathological processes1. The endothelial cell-specific mitogen vascular endothelial growth factor (VEGF)2,3 is a major mediator of pathological angiogenesis4–6. Also, the expression o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::219e7e19ef462b190cebd74802132e5c
https://doi.org/10.1038/380439a0
https://doi.org/10.1038/380439a0
Autor:
Lyn Powell-Braxton, P Hollingshead, Sharon Pitts-Meek, M Dowd, C Warburton, D Dalton, Timothy A. Stewart, N Gillett
Publikováno v:
Genes & Development. 7:2609-2617
IGF-I is a pleiotropic hormone reported to affect linear growth, glucose metabolism, organ homeostasis, and the immune and neurologic systems. In contrast to IGF-II, IGF-I is expressed at low levels embryonically and has been thought to be more impor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c16eaa24d73f87bed07cbc108d418df
https://doi.org/10.1101/gad.7.12b.2609
https://doi.org/10.1101/gad.7.12b.2609
Autor:
Timothy J. Lyons, Samar M. Hammad, Wesley Won, Lyn Powell-Braxton, Leslie Eldridge, James D Otvos
Publikováno v:
Metabolism: clinical and experimental. 52(7)
Dyslipidemia accelerates vascular complications of diabetes. Nuclear magnetic resonance (NMR) analysis of lipoprotein subclasses is used to evaluate a mouse model of human familial hypercholesterolemia +/- streptozotocin (STZ)-induced diabetes. A dou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc081075b265d7e403fe4a11aadbe8ea
https://pubmed.ncbi.nlm.nih.gov/12870170
https://pubmed.ncbi.nlm.nih.gov/12870170