Zobrazeno 1 - 10
of 620
pro vyhledávání: '"Lymphozyt"'
Autor:
Schempp, Rebekka Maria
Accumulation of lipid droplets (LD) and ceramides (Cer) is associated with the pathogenesis of metabolic dysfunction-associated steatotic liver disease (MASLD) a condition frequently co-occurring with type 2 diabetes and diminished immune functionali
Autor:
Schöl, Marie Lydia
Neutral sphingomyelinase 2 (NSM2), encoded by the phosphodiesterase 3 (SMPD3) gene, is a key enzyme in the sphingolipid metabolism. It catalyzes the conversion of sphingomyelin into ceramide. NSM2 activation and ceramide production play pivotal roles
Autor:
Waghmare, Trushnal
The glycoprotein leukosialin, commonly known as CD43, is heavily glycosylated and one of the major glycocalyx proteins expressed on leukocytes. CD43 is pivotal in directing cell signals and negatively affecting T-cell stimulation and proliferation. I
Autor:
Zoller, Davina Hedda
Bei der schubförmig-remittierenden Multiplen Sklerose (RRMS) und der sekundär progredienten Multiplen Sklerose (SPMS) wurden ektopische lymphoide Follikel (eLF) im zentralen Nervensystem (ZNS) nachgewiesen. Von unserer Gruppe konnte in diesen eLF k
Multiple Myeloma remains an incurable disease of clonally expanding malignant plasma cells. The bone marrow microenvironment harbors treatment resistant myeloma cells, which eventually lead to a disease relapse in patients. CD4+FoxP3+ regulatory T ce
Autor:
Woidich, Robert
In der Pathogenese der Psoriasis spielen IL 17 und die Plastizität von Tregs zu Th17 Zellen mit Produktion proinflammatorischer Zytokine sowie die möglicherweise reduzierte suppressive Funktion von Tregs eine entscheidende Rolle. Wir versuchten dah
Autor:
Gamboa Vargas, Juan Fernando
In this work we expanded upon a study from our group where a ligand-based TNF-α mutein was developed to engage specifically TNFR2 and not TNFR1 activating Tregs and expanding them, which in an allo-HCT context conferred protection from GvHD. Fusing
Autor:
Fischer, Jonas Maria
Innerhalb der Juvenilen Idiopathischen Arthritis (JIA) bilden Patienten mit Antinukleären Antikörpern (ANA) Subgruppen-übergreifend eine klinisch homogene Erkrankungsgruppe. Ob diesen klinischen Gemeinsamkeiten jedoch auch eine einheitliche Pathog
Autor:
Cruz de Casas, Paulina
The immune system is responsible for the preservation of homeostasis whenever a given organism is exposed to distinct kinds of perturbations. Given the complexity of certain organisms like mammals, and the diverse types of challenges that they encoun
Autor:
Peña Mosca, María Josefina
After priming in Peyer's patches (PPs) and mesenteric lymph nodes (mLN) T- cells infiltrate the intestine through lymphatic draining and homing through the bloodstream. However, we found that in mouse models of acute graft-versus-host disease (GvHD),