Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Lymphocytic Leukemias"'
Autor:
Mahdieh Darvish-Khezri, Mohsen Tehrani, Hossein Ghalehnoei, Saeid Taghiloo, Amir Kahrizi, Hossein Asgarian-Orman, Abolghasem Ajami, Reza Valadan
Publikováno v:
Journal of Mazandaran University of Medical Sciences, Vol 34, Iss 238, Pp 48-56 (2024)
Background and purpose: Chronic Lymphocytic Leukemia (CLL) is a lymphoproliferative disorder characterized by the clonal and malignant proliferation of mature B-cells within the peripheral blood, bone marrow, and secondary lymphoid tissues. In chroni
Externí odkaz:
https://doaj.org/article/dece11e8917b47999a06932b78d38e49
Akademický článek
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Akademický článek
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Publikováno v:
Brazilian Journal of Development. 6:102464-102472
As leucemias linfoblastica sao caracterizadas por uma producao elevada de celulas imaturas da linhagem linfoide, subdivididas em celulas B e T, e fase aguda (LLA) ou cronica (LLC). A expressao miRNA esta correlacionadas a alteracoes citogeneticas esp
Autor:
Theodoros Moysiadis, Nikos Papakonstantinou, José I. Martín-Subero, Fotis Psomopoulos, Panagoula Kollia, Elias Campo, Martí Duran-Ferrer, Vicente Chapaprieta, Maria Tsagiopoulou, Kostas Stamatopoulos
Publikováno v:
Haematologica
Autor:
Ιoannis Kotsianidis, Anna Christoforidou, George Vrachiolias, Zoe Bezirgiannidou, Menelaos Papoutselis, Emmanouil Spanoudakis
Publikováno v:
Leukemialymphoma. 61(3)
Prolymphocytic leukemia (PLL) is a rare disorder, comprising less than 1% of chronic lymphocytic leukemias [1]. T-cell origin is more common, while B-PLL is rarely encountered. It is mostly affecti...
Publikováno v:
Gene Expression. 16:129-135
The first transgenic mouse of the TCL1 oncogene was described more than 15 years ago, and since then, the overexpression of the gene in T- and B-cells in vivo has been extensively studied to reveal the molecular details in the pathogenesis of some ly
Autor:
Antonio Cuneo, Elisabetta Melloni, Rebecca Voltan, Gian Matteo Rigolin, Giorgio Zauli, Paola Secchiero, Raffaella Bosco, Sandra Marmiroli
Publikováno v:
Clinical Cancer Research. 17:762-770
Purpose: To analyze the effect of the combination of Dasatinib, a multikinase inhibitor, plus Nutlin-3, a nongenotoxic activator of the p53 pathway, in primary B chronic lymphocytic leukemia (B-CLL) patient samples and B leukemic cell line models. Ex
Publikováno v:
Bulletin of mathematical biology. 80(5)
Modified T cells that have been engineered to recognize the CD19 surface marker have recently been shown to be very successful at treating acute lymphocytic leukemias. Here, we explore four previous approaches that have used ordinary differential equ
Autor:
Giovanni Roti, Kimberly Stegmaier
Publikováno v:
Critical Reviews™ in Oncogenesis. 16:103-115
NOTCH1 is a well-validated target in hematopoietic malignancy, with NOTCH1 activating mutations identified in more than 50% of T-cell acute lymphoblastic leukemias. Moreover, a recent report has identified NOTCH1 activating mutations in 12% of chroni