Manifold Roles of CCR7 and Its Ligands in the Induction and Maintenance of Bronchus-Associated Lymphoid Tissue

Autor: Sanjiv A. Luther, Gerd Sutter, Reinhold Förster, Anja Bubke, Marc Permanyer, Stefanie Willenzon, Berislav Bošnjak, Henrike Fleige, Jasmin Ristenpart

Publikováno v: Cell reports, vol. 23, no. 3, pp. 783-795
Cell Reports, Vol 23, Iss 3, Pp 783-795 (2018)

Summary: The processes underlying the development and maintenance of tertiary lymphoid organs are incompletely understood. Using a Ccr7 knockout/knockin approach, we show that spontaneous bronchus-associated lymphoid tissue (BALT) formation can be ca

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c34892c25d581f23ba5b5724047ddf4
https://doi.org/10.1016/j.celrep.2018.03.072

Early Antiretroviral Therapy Preserves Functional Follicular Helper T and HIV-Specific B Cells in the Gut Mucosa of HIV-1-Infected Individuals

Autor: Valérie Lorin, Mathieu Surenaud, Cyril Planchais, Hugo Mouquet, Mathieu Fusaro, Sophie Hue, Marie-Hélène Delfau-Larue, Nabila Seddiki, Clara Ibanez, Laurent Hocqueloux, Michael J. Levy, Thierry Prazuck, S. Gallien, Yves Levy, Ayrin Kök, Christiane Copie, Jean-Daniel Lelièvre, Laurent Lefrou

Publikováno v: Journal of Immunology
Journal of Immunology, 2018, 200 (10), pp.3519-3529. ⟨10.4049/jimmunol.1701615⟩
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2018, 200 (10), pp.3519-3529. ⟨10.4049/jimmunol.1701615⟩

HIV-1 infection is associated with B cell dysregulation and dysfunction. In HIV-1–infected patients, we previously reported preservation of intestinal lymphoid structures and dendritic cell maturation pathways after early combination antiretroviral

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2622102e5901a8a1bf6c99603c6ba9c4
https://hal-pasteur.archives-ouvertes.fr/pasteur-02634634/document

Pre-ART HIV-1 DNA in CD4+ T cells correlates with baseline viro-immunological status and outcome in patients under first-line ART

Autor: Ceccherini-Silberstein, F, Cozzi Lepri, A, Alteri, C, Merlini, E, Surdo, M, Marchetti, G, Capobianchi, Mr, De Luca, A, Gianotti, N, Viale, P, Andreoni, M, Antinori, A, Perno, Cf, d'Arminio Monforte, A, Castagna, A, Castelli, F, Cauda, R, Di Perri, G, Galli, M, Iardino, R, Ippolito, G, Lazzarin, A, Marchetti, Gc, Rezza, G, von Schloesser, F, Cozzi-Lepri, A, Girardi, E, Lo Caputo, S, Mussini, C, Puoti, M, Ammassari, A, Balotta, C, Bandera, A, Bonfanti, P, Bonora, S, Borderi, M, Calcagno, A, Calza, L, Cingolani, A, Cinque, P, Di Biagio, A, Gori, A, Guaraldi, G, Lapadula, G, Lichtner, M, Madeddu, G, Maggiolo, F, Marcotullio, S, Monno, L, Nozza, S, Quiros Roldan, E, Rossotti, R, Rusconi, S, Santoro, Mm, Saracino, A, Zaccarelli, M, Fanti, I, Galli, L, Lorenzini, P, Rodano, A, Shanyinde, M, Tavelli, A, Carletti, F, Carrara, S, Di Caro, A, Graziano, S, Petrone, F, Prota, G, Quartu, S, Truffa, S, Giacometti, A, Costantini, A, Barocci, V, Angarano, G, Santoro, C, Suardi, C, Donati, V, Verucchi, G, Minardi, C, Quirino, T, Abeli, C, Manconi, Pe, Piano, P, Cacopardo, B, Celesia, B, Vecchiet, J, Falasca, K, Sighinolfi, L, Segala, D, Blanc, P, Vichi, F, Cassola, G, Viscoli, C, Alessandrini, A, Bobbio, N, Mazzarello, G, Mastroianni, C, Pozzetto, I, Molteni, C, Chiodera, A, Milini, P, Nunnari, G, Pellicanò, G, Rizzardini, G, Moioli, Mc, Piolini, R, Ridolfo, Al, Salpietro, S, Tincati, C, Puzzolante, C, Chirianni, A, Borgia, G, Esposito, V, Orlando, R, Bonadies, G, Di Martino, F, Gentile, I, Maddaloni, L, Cattelan, Am, Marinello, S, Cascio, A, Colomba, C, Baldelli, F, Schiaroli, E, Parruti, G, Sozio, F, Magnani, G, Ursitti, Ma, Acinapura, R, Baldin, G, Capozzi, M, Cicalini, S, Cristaudo, A, Fontanelli Sulekova, L, Iaiani, G, Latini, A, Mastrorosa, I, Plazzi, Mm, Savinelli, S, Vergori, A, Vullo, V, Cecchetto, M, Viviani, F, Bagella, P, Rossetti, B, Franco, A, Fontana Del Vecchio, R, Francisci, D, Di Giuli, C, Caramello, P, Orofino, Gc, Sciandra, M, Bassetti, M, Londero, A, Pellizzer, G, Manfrin, V, Starnini, G, Ialungo, A.

Objectives We evaluated the association between pre-ART HIV DNA and HIV-infected participant characteristics at baseline as well as with their response to first-line ART. Methods Four hundred and thirty-three patients from the ICONA cohort, starting

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::602a7c9b321f07599c9698e9a9af3dbe
http://hdl.handle.net/11391/1437758

JCV-specific T-cells producing IFN-gamma are differently associated with PmL occurrence in HIV patients and liver transplant recipients

Autor: Chiara Agrati, Izzo, L., Berno, G., Cimini, E., Bordoni, V., Giancola, M. L., Baldini, F., Colasanti, M., Ettorre, G. M., Izzo, P., Pugliese, F., Angrisani, M., Di Cello, P., Capobianchi, M. R., Bolognese, A.

Publikováno v: Scopus-Elsevier
Europe PubMed Central

Aim of this work was to investigate a possible correlation between the frequency of JCV-specific T-cells and PML occurrence in HIV-infected subjects and in liver transplant recipients. A significant decrease of JCV-specific T-cells was observed in HI

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5a044817969165181fba1b6f8b5dca65
https://pubmed.ncbi.nlm.nih.gov/25742151

Imporved biological activity of antisense oligonucleotides conjugated to a fusogenic peptide

Autor: Bernard Lebleu, Anne-Marie Aubertin, J P Bongartz, P G Milhaud

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 1994, 22 (22), pp.4681--8. ⟨10.1093/nar/22.22.4681⟩

Recently several groups reported a dramatic improvement of reporter gene transfection efficiency using a fusogenic peptide, derived from the Influenza hemagglutinin envelop protein. This peptide changes conformation at acidic pH and destabilizes the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d43a2b88ab4d41c1ab53f90015772962
https://doi.org/10.1093/nar/22.22.4681