Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lymphocytes/pathology"'
Autor:
Christelle Le Dantec, Cristina Adela Iuga, Ioana-Ecaterina Pralea, Melanie Cornen, Wesley H. Brooks, Jacques-Olivier Pers, Hussam Saad, Tiffany Bergot, Adrian Tempescul, Anne Bordron, Delphine G. Bernard, Jean-Christophe Ianotto, Cristina Bagacean, Mihnea Zdrenghea, Christian Berthou, Yves Renaudineau
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, 2022, 111 (2), pp.313-325. ⟨10.1002/JLB.4HI0620-392R⟩
Journal of Leukocyte Biology, 2022, 111 (2), pp.313-325. ⟨10.1002/JLB.4HI0620-392R⟩
Chronic lymphocytic leukemia (CLL) is characterized by significant biologic and clinical heterogeneity. This study was designed to explore CLL B-cells’ proteomic profile in order to identify biologic processes affected at an early stage and during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89c0e8a083104e71222aa68c222ad12b
https://doi.org/10.1002/jlb.4hi0620-392r
https://doi.org/10.1002/jlb.4hi0620-392r
Autor:
Yasin Ozdemir, Ibrahim Toprak, Emine Kilic-Toprak, Sadettin Çalışkan, Fatih Altıntaş, Onder Demirtas, Vural Kucukatay
Publikováno v:
Eye & Contact Lens: Science & Clinical Practice. 45:399-404
Objectives: To perform a systemic investigation on oxidative stress and DNA damage in patients with primary pterygium. Methods: This prospective cross-sectional study included 32 patients with primary pterygium (60.1 +/- 2.0 years of age) and 33 age-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03fc26b60a164babbfd3fd2e363b93c1
https://doi.org/10.1097/icl.0000000000000620
https://doi.org/10.1097/icl.0000000000000620
Autor:
Charlotte G Smith, Francesca Barone, Saba Asam, David H. Gardner, Andrew Filer, Bridget Glaysher, David Roulois, Valentina Iannizzotto, Joana Campos, Frédéric Mourcin, Jason D. Turner, Mark Coles, Christopher D. Buckley, Marvin Sylvestre, Benjamin A Fisher, Karin Tarte, Simon J. Bowman, Douglas T. Fearon, Saba Nayar, Sanjiv A. Luther
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (27), pp.13490-13497. ⟨10.1073/pnas.1905301116⟩
Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 27, pp. 13490-13497
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (27), pp.13490-13497. ⟨10.1073/pnas.1905301116⟩
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences, 2019, 116 (27), pp.13490-13497. ⟨10.1073/pnas.1905301116⟩
Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 27, pp. 13490-13497
Proceedings of the National Academy of Sciences of the United States of America, 2019, 116 (27), pp.13490-13497. ⟨10.1073/pnas.1905301116⟩
Significance TLS, which are clusters of lymphocytes and stromal cells observed at sites of chronic inflammation, play a key role in sustaining disease progression in autoimmune conditions. While the role of lymphocytes in these structures has been st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcf5faf2567b08201f1df1bdd162aa98
http://europepmc.org/articles/PMC6613169
http://europepmc.org/articles/PMC6613169
Autor:
Christian Matek, Carsten Marr, Luuk F P Jacobs, Michèle C. Buck, Dragan Bošnački, Jens P E Schouten
Publikováno v:
Sci. Rep. 11:7995 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, 11(1):7995. Nature Publishing Group
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Scientific Reports, 11(1):7995. Nature Publishing Group
Scientific Reports
Convolutional neural networks (CNNs) excel as powerful tools for biomedical image classification. It is commonly assumed that training CNNs requires large amounts of annotated data. This is a bottleneck in many medical applications where annotation r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab417fcf093e20fc3a05413b9b085d24
https://doi.org/10.1038/s41598-021-86995-5
https://doi.org/10.1038/s41598-021-86995-5
Publikováno v:
Mutation research. Reviews in mutation research. 786
Auto-immune diseases (AUD) are characterized by an immune response to antigenic components of the host itself. The etiology of AUD is not well understood. The available evidence points to an interaction between genetic, epigenetic, environmental, inf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e4061d91ea2b759924ed5e5797201be
https://pubmed.ncbi.nlm.nih.gov/33339583
https://pubmed.ncbi.nlm.nih.gov/33339583
Publikováno v:
Journal of Leukocyte Biology
Journal of Leukocyte Biology, 2020, 108 (4), pp.1067-1079. ⟨10.1002/JLB.1MR0520-746R⟩
Journal of Leukocyte Biology, 2020, 108 (4), pp.1067-1079. ⟨10.1002/JLB.1MR0520-746R⟩
Innovative immunotherapies based on immune checkpoint targeting antibodies and engineered T cells are transforming the way we approach cancer treatment. However, although these T cell centered strategies result in marked and durable responses in pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc95014385f55a1f07ac5fb0e34df16
https://pubmed.ncbi.nlm.nih.gov/32620049
https://pubmed.ncbi.nlm.nih.gov/32620049
Autor:
Neven Zarkovic, Antonia Jakovcevic, Ana Mataic, Morana Jaganjac, Tea Vukovic, Georg Waeg, Kamelija Zarkovic
Publikováno v:
Cells, Vol 11, Iss 444, p 444 (2022)
Cells
Cells; Volume 11; Issue 3; Pages: 444
Cells
Cells; Volume 11; Issue 3; Pages: 444
A recent comparison of clinical and inflammatory parameters, together with biomarkers of oxidative stress, in patients who died from aggressive COVID-19 and survivors suggested that the lipid peroxidation product 4-hydroxynonenal (4-HNE) might be det
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21fe8e23b27d41c9e3b7e62e39a9caa8
https://doi.org/10.3390/cells11030444
https://doi.org/10.3390/cells11030444
Autor:
Lucy Catteau, Nicolas Dauby, Marion Montourcy, Emmanuel Bottieau, Joris Hautekiet, Els Goetghebeur, Sabrina van Ierssel, Els Duysburgh, Herman Van Oyen, Chloé Wyndham-Thomas, Dominique Van Beckhoven, Kristof Bafort, Leïla Belkhir, Nathalie Bossuyt, Philippe Caprasse, Vincent Colombie, Paul De Munter, Jessika Deblonde, Didier Delmarcelle, Mélanie Delvallee, Rémy Demeester, Thierry Dugernier, Xavier Holemans, Benjamin Kerzmann, Pierre Yves Machurot, Philippe Minette, Jean-Marc Minon, Saphia Mokrane, Catherine Nachtergal, Séverine Noirhomme, Denis Piérard, Camelia Rossi, Carole Schirvel, Erica Sermijn, Frank Staelens, Filip Triest, Nina Van Goethem, Jens Van Praet, Anke Vanhoenacker, Roeland Verstraete, Elise Willems
Publikováno v:
International Journal of Antimicrobial Agents
International journal of antimicrobial agents
International journal of antimicrobial agents, 56 (4
International journal of antimicrobial agents, Vol. 56, no.4, p. 106144 [1-8] (2020)
International journal of antimicrobial agents
International journal of antimicrobial agents, 56 (4
International journal of antimicrobial agents, Vol. 56, no.4, p. 106144 [1-8] (2020)
Highlights • Hydroxychloroquine (HCQ) 2400 mg over 5 days was used in Belgium for COVID-19. • Impact of HCQ on mortality among 8075 patients with COVID-19 was assessed. • Lower mortality in HCQ-treated patients as compared to supportive care.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4473fee635cf334f6edcf0376c8dea9
https://doi.org/10.1016/j.ijantimicag.2020.106144
https://doi.org/10.1016/j.ijantimicag.2020.106144
Autor:
Guido Silvestri, Julie Garibal, Vasco Rodrigues, Alain Pruvost, Shahul Mouhamad, Mireille Laforge, Valérie Monceaux, Jérôme Estaquier, Anna Senik, Bruno Hurtrel, Henintsoa Rabezanahary, Ricardo Silvestre, Anabela Cordeiro-da-Silva, Laure Campillo-Gimenez, Marie-Christine Cumont
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2018, 128 (4), pp.1627-1640. ⟨10.1172/JCI95127⟩
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Journal of Clinical Investigation
Journal of Clinical Investigation, American Society for Clinical Investigation, 2018, 128 (4), pp.1627-1640. ⟨10.1172/JCI95127⟩
Apoptosis has been proposed as a key mechanism responsible for CD4+ T cell depletion and immune dysfunction during HIV infection. We demonstrated that Q-VD-OPH, a caspase inhibitor, inhibits spontaneous and activation-induced death of T cells from SI
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4a722532b12bdd83ff678a61fe5e8c8
https://europepmc.org/articles/PMC5873886/
https://europepmc.org/articles/PMC5873886/
Autor:
Jean-François Emile, Catherine Julié, Karine Le Malicot, Come Lepage, Josep Tabernero, Enrico Mini, Gunnar Folprecht, Jean-Luc Van Laethem, Stéphanie Dimet, Camille Boulagnon-Rombi, Marc-Antoine Allard, Frédérique Penault-Llorca, Jaafar Bennouna, Pierre Laurent-Puig, Julien Taieb, Josef Thaler, Richard Greil, Johannes Gaenzer, Wolfgang Eisterer, Joerg Tschmelitsch, Felix Keil, Hellmut Samonigg, August Zabernigg, Franz Schmid, Günther Steger, Robert Steinacher, Johannes Andel, Björn Jagdt, Alois Lang, Michael Fridrik, Reinhold Függer, Friedrich Hofbauer, Ewald Woell, Dietmar Geissler, Alfred Lenauer, Manfred Prager, Geert D'Haens, Gauthier Demolin, Joseph Kerger, Guido Deboever, Gilbert Ghillebert, Marc Polus, Eric Van Cutsem, Hassan Rezaie Kalantari, Thierry Delaunoit, Jean Charles Goeminne, Marc Peeters, Philippe Vergauwe, Ghislain Houbiers, Yves Humblet, Jos Janssens, Dirk Schrijvers, Erik Vanderstraeten, Jan Vermorken, Daniel Van Daele, Michel Ferrante, Frederic Forget, Alain Hendlisz, Mette Yilmaz, Svend Erik Nielsen, Lene Vestermark, Jim Larsen, Mohamed-Ayman Zawadi, Olivier Bouche, Laurent Mineur, Jaafar Bennouna-Louridi, Louis Marie Dourthe, Marc Ychou, Eveline Boucher, Denis Pezet, Francoise Desseigne, Michel Ducreux, Patrick Texereau, Laurent Miglianico, Philippe Rougier, Serge Fratte, Charles-Briac Levache, Yacine Merrouche, Stephen Ellis, Christophe Locher, Jean-Francois Ramee, Claire Garnier, Frederic Viret, Bruno Chauffert, Isabelle Cojean-Zelek, Pierre Michel, Cedric Lecaille, Christian Borel, Jean-Francois Seitz, Denis Smith, Catherine Lombard-Bohas, Thierry Andre, Jean-Marc Gornet, Francine Fein, Marie-Aude Coulon-Sfairi, Marie-Christine Kaminsky, Jean-Paul Lagasse, Dominique Luet, Pierre-Luc Etienne, Mohamed Gasmi, Andre Vanoli, Suzanne Nguyen, Thomas Aparicio, Hervé Perrier, Noel Stremsdoerfer, Philippe Laplaige, Dominique Arsene, Dominique Auby, Laurent Bedenne, Romain Coriat, Bernard Denis, Patrick Geoffroy, Gilles Piot, Yves Becouarn, Gilbert Bordes, Gael Deplanque, Olivier Dupuis, Frederic Fruge, Rosine Guimbaud, Thierry Lecomte, Gérard Lledo, Iradej Sobhani, Amani Asnacios, Ahmed Azzedine, Christophe Desauw, Marie-Pierre Galais, Dany Gargot, You-Heng Lam, Abakar Abakar-Mahamat, Jean-Francois Berdah, Sylviane Catteau, Marie-Christine Clavero-Fabri, Jean-Francois Codoul, Jean-Louis Legoux, Denis Goldfain, Pierre Guichard, Denis Pere Verge, Jocelyne Provencal, Bruno Vedrenne, Catherine Brezault-Bonnet, Denis Cleau, Jean-Paul Desir, David Fallik, Bruno Garcia, Marie-Hélène Gaspard, Dominique Genet, Johannes Hartwig, Yves Krummel, Tamara Matysiak Budnik, Vanessa Palascak-Juif, Harizo Randrianarivelo, Yves Rinaldi, Albert Aleba, Ariane Darut-Jouve, Aimery de Gramont, Herve Hamon, Frederic Wendehenne, Axel Matzdorff, Michael Konrad Stahl, Wolfgang Schepp, Martin Burk, Lothar Mueller, Michael Geissler, Luisa Mantovani-Loeffler, Thomas Hoehler, Walter Asperger, Hendrik Kroening, Ludwig Fischer von Weikersthal, Stefan Fuxius, Matthias Groschek, Johannes Meiler, Tanja Trarbach, Jacqueline Rauh, Nicolas Ziegenhagen, Albrecht Kretzschmar, Ullrich Graeven, Arnd Nusch, Goetz von Wichert, Ralf-Dieter Hofheinz, Gerhard Kleber, Karl-Heinz Schmidt, Ursula Vehling-Kaiser, Claudia Baum, Jochen Schuette, Georg Martin Haag, Wilhelm Holtkamp, Jochen Potenberg, Tobias Reiber, Georg Schliesser, Hans-Joachim Schmoll, Wolfgang Schneider-Kappus, Wolfgang Abenhardt, Claudio Denzlinger, Jan Henning, Bartscht Marxsen, Hans Guenter Derigs, Helmut Lambertz, Ingulf Becker-Boost, Karel Caca, Christian Constantin, Thomas Decker, Henning Eschenburg, Sigrun Gabius, Holger Hebart, Albrecht Hoffmeister, Heinz-August Horst, Stephan Kremers, Malte Leithaeuser, Sebastian Mueller, Siegfried Wagner, Severin Daum, Frank Schlegel, Martina Stauch, Volker Heinemann, Evaristo Maiello, Luciano Latini, Alberto Zaniboni, Dino Amadori, Giuseppe Aprile, Sandro Barni, Rodolfo Mattioli, Andrea Martoni, Rodolfo Passalacqua, Mario Nicolini, Enzo Pasquini, Carla Rabbi, Enrico Aitini, Alberto Ravaioli, Carlo Barone, Guido Biasco, Stefano Tamberi, Angelo Gambi, Claudio Verusio, Marina Marzola, Giorgio Lelli, Corrado Boni, Stefano Cascinu, Paolo Bidoli, Massimo Vaghi, Giorgio Cruciani, Francesco Di Costanzo, Alberto Sobrero, Roberto Petrioli, Massimo Aglietta, Oscar Alabiso, Federico Capuzzo, Alfredo Falcone, Domenico Cristi Corsi, Roberto Labianca, Stefania Salvagni, Silvana Chiara, Libero Ciuffreda, Francesco Ferraù, Francesco Giuliani, Sara Lonardi, Nicola Gebbia, Giovanni Mantovani, Evaristo Sanches, Juan Carlos Mellidez, Pedro Santos, Joao Freire, Cristina Sarmento, Luis Costa, Antonio Moreira Pinto, Sergio Barroso, Jorge Espirito Santo, Fátima Guedes, Amélia Monteiro, Anabela Sa, Irene Furtado, Ramon Salazar, Enrique Aranda Aguilar, Fernando Rivera Herrero, Javier Sastre Valera, Manuel Valladares Ayerbes, Jaime Feliu Batlle, Silvia Gil, Albert Abad Esteve, Carlos Garcia-Giron, Guillermo Lopez Vivanco, Antonia Salud Salvia, Vicente Alonso Orduña, Ruth Vera Garcia, Javier Gallego, Bartomeu Massuti Sureda, Jordi Remon, Maria Jose Safont Aguilera, Luis Cirera Nogueras, Bernado Queralt Merino, Cristina Gravalos Castro, Purificacion Martinez de Prado, Carlos Pijaume Pericay, Manuel Constenla Figueiras, Inmaculada Guasch Jordan, Maria Jose Gome Reina, Amelia Lopez-Ladron Garcia, Antonio Arrivi Garcia-Ramos, Andres Cervantes, Carlos Fernandez Martos, Eugenio Marcuello Gaspar, Ines Cabezas Montero, Pilar Escudero Emperador, Ana Leon Carbonero, Manuel Gallen Castillo, Teresa Garcia Garcia, Jose Garcia Lopez, Encarnacion Gonzalez Flores, Monica Guillot Morales, Marta Llanos Muñoz, Ana López Martín, Joan Maurel, Juan Carlos Camara, Rosario Dueñas Garcia, Mercedes Salgado, Isabel Hernandez Busquier, Teresa Checa Ruiz, Adelaida Lacasta Muñoa, Miquel Nogue Aliguer, Amalia Velasco Ortiz de Taranco, Miguel Mendez Ureña, Ferran Losa Gaspa, Jose Juan Ponce, Carlos Bosch Roig, Pedro Valero Jimenez, Antonio Galan Brotons, Santiago Albiol Rodriguez, Jose Ales Martinez, Liliana Canosa Ruiz, Margarita Centelles Ruiz, John Bridgewater, Rob Glynne-Jones, Saad Tahir, Tamas Hickish, Jim Cassidy, Leslie Samuel
Publikováno v:
European journal of cancer (Oxford, England : 1990)
European journal of cancer (Oxford, England : 1990), 2017, 82, pp.16-24. 〈http://www.sciencedirect.com/science/article/pii/S0959804917309528?via%3Dihub#!〉. 〈10.1016/j.ejca.2017.04.025〉
European Journal of Cancer
European Journal of Cancer, Elsevier, 2017, 82, pp.16-24. ⟨10.1016/j.ejca.2017.04.025⟩
the PETACC8 Study Investigators 2017, ' Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX ', European Journal of Cancer, vol. 82, pp. 16-24 . https://doi.org/10.1016/j.ejca.2017.04.025
European journal of cancer (Oxford, England : 1990), 2017, 82, pp.16-24. 〈http://www.sciencedirect.com/science/article/pii/S0959804917309528?via%3Dihub#!〉. 〈10.1016/j.ejca.2017.04.025〉
European Journal of Cancer
European Journal of Cancer, Elsevier, 2017, 82, pp.16-24. ⟨10.1016/j.ejca.2017.04.025⟩
the PETACC8 Study Investigators 2017, ' Prospective validation of a lymphocyte infiltration prognostic test in stage III colon cancer patients treated with adjuvant FOLFOX ', European Journal of Cancer, vol. 82, pp. 16-24 . https://doi.org/10.1016/j.ejca.2017.04.025
IF 6.029; International audience; BackgroundThe prognostic value of lymphocyte infiltration (LI) of colorectal carcinoma (CC) has been demonstrated by several groups. However, no validated test is currently available for clinical practice. We previou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecdb0610ff4a5940fb2f72afe8030fe
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01579009
https://hal-univ-bourgogne.archives-ouvertes.fr/hal-01579009