Zobrazeno 1 - 10
of 5 968
pro vyhledávání: '"Lymphoblastic leukaemia"'
Publikováno v:
Onco, Vol 4, Iss 3, Pp 232-240 (2024)
The use of chimeric antigen receptors (CAR T-cells) for the treatment of patients with malignant haematological diseases has become a well-established application for conditions such as refractory or relapsed B-cell acute lymphoblastic leukaemia (B-A
Externí odkaz:
https://doaj.org/article/681b84c48d244b28a1b50f50a66d3c15
Autor:
Eugenia Licari, Giulia Cricrì, Mario Mauri, Francesca Raimondo, Laura Dioni, Chiara Favero, Alice Giussani, Rita Starace, Silvia Nucera, Andrea Biondi, Rocco Piazza, Valentina Bollati, Erica Dander, Giovanna D’Amico
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Extracellular vesicles (EVs) are a new mechanism of cellular communication, by delivering their cargo into target cells to modulate molecular pathways. EV-mediated crosstalk contributes to tumor survival and resistance to cellular stress. Ho
Externí odkaz:
https://doaj.org/article/4d43d19d282143e3b833d35e580de20b
Autor:
Won Kee Ahn, Kyunghee Yu, Hongkyung Kim, Seung-Tae Lee, Jong Rak Choi, Jung Woo Han, Chuhl Joo Lyu, Seungmin Hahn, Saeam Shin
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Background Assessment of measurable residual disease (MRD) is an essential prognostic tool for B-lymphoblastic leukaemia (B-ALL). In this study, we evaluated the utility of next-generation sequencing (NGS)–based MRD assessment in real-worl
Externí odkaz:
https://doaj.org/article/db7ea2e458184b0a9ef0acb4ef0fcfa3
Autor:
Huidi Wang, Yajie Zhang, Qianyi Zhou, Lihua Yu, Jingxiang Fu, Danna Lin, Lulu Huang, Xiaorong Lai, Li Wu, Jingxin Zhang, Juan Zi, Xu Liao, Siying Huang, Yugu Xie, Yan He, Lihua Yang
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 23, Iss 1, Pp 1-10 (2024)
Abstract Background Emerging evidence has indicated a link between the gut microbiota and acute lymphoblastic leukaemia (ALL). However, the acute changes in gut microbiota during chemotherapy and the predictive value of baseline gut microbiota in inf
Externí odkaz:
https://doaj.org/article/963d697a63f6470f9a5abb552b31eb94
Publikováno v:
Nigerian Journal of Paediatrics, Vol 40, Iss 4, Pp 431-433 (2024)
Background: Acute Lymphoblastic Leukaemia in children commonly presents with osteo articular manifestations that may mimic Juvenile Idiopathic Arthritis. This may create considerable diagnostic difficulty and lead to delay in commencing appropriate
Externí odkaz:
https://doaj.org/article/c902222cd08543ea8436695502d52816
Publikováno v:
Nigerian Journal of Paediatrics, Vol 41, Iss 3, Pp 244-246 (2024)
Childhood acute lymphoblastic leukaemia, (ALL) is increasingly reported to present in an atypical fashion which may have significant implications for treatment outcomes and survival. This case report presents a Nigerian child who’s clinical and r
Externí odkaz:
https://doaj.org/article/11b19a1148524d6eaba7a4df9f536fbf
Autor:
Xiaowen Gong, Tianyuan Hu, Qiujin Shen, Luyang Zhang, Wei Zhang, Xueou Liu, Suyu Zong, Xiaoyun Li, Tiantian Wang, Wen Yan, Yu Hu, Xiaoli Chen, Jiarui Zheng, Aoli Zhang, Junxia Wang, Yahui Feng, Chengwen Li, Jiao Ma, Xin Gao, Zhen Song, Yingchi Zhang, Robert Peter Gale, Xiaofan Zhu, Junren Chen
Publikováno v:
eJHaem, Vol 5, Iss 2, Pp 333-345 (2024)
Abstract ETV6::RUNX1 is the most common fusion gene in childhood acute lymphoblastic leukaemia (ALL) and is associated with favorable outcomes, especially in low‐risk children. However, as many as 10% of children relapse within 3 years, and such ea
Externí odkaz:
https://doaj.org/article/2d19a6eea3e6454582900e1f537d85bf
Autor:
Aleksandra Dembowska, Maciej Dubaj, Karol Bigosiński, Mateusz Raniewicz, Małgorzata Mitura-Lesiuk
Publikováno v:
Pediatria Polska, Vol 99, Iss 1, Pp 66-70 (2024)
Cancer is the second leading cause of death in the paediatric population after injuries. 3–10% of them are multiple primary malignant neoplasms, which are a huge problem both in diagnosis and treatment. We present a case of a boy, nearly 2 years ol
Externí odkaz:
https://doaj.org/article/4df53c2ef3904e6095d84872747955f4
Autor:
Thaís Muniz Vasconcelos, Dany Mesa, Luiza Souza Rodrigues, Érika Medeiros dos Santos, Damaris Krul, Adriele Celine Siqueira, Renata Barbosa Vahia de Abreu, Fábio de Araújo Motta, Danieli Conte, Libera Maria Dalla-Costa
Publikováno v:
Journal of Global Antimicrobial Resistance, Vol 36, Iss , Pp 41-44 (2024)
ABSTRACT: Objectives: We aimed to investigate an outbreak of vancomycin-resistant Enterococcus faecium (VREfm) in paediatric patients from Hospital Pequeno Príncipe. The susceptibility profile was determined, and whole-genome sequencing (WGS) was us
Externí odkaz:
https://doaj.org/article/c5345dc6e0f7430ba15cda0a27a45429
Autor:
Punit Jain, Poonam Jain, Robert S. Ohgami, Veena Pawar, Kunal Sehgal, Pradnya Chaudhari, Ravindra Nikalji, Tejinder Singh, Vipin Khandelwal, Sanjay Khare, Vaishali Lokhande, Ashwathy Haridas, Laxman Jessani, Kanika Khandelwal
Publikováno v:
eJHaem, Vol 5, Iss 1, Pp 251-255 (2024)
Abstract Primary renal involvement by T lymphoblasts is rare among adults with T acute lymphoblastic leukaemia. We report a 28‐year‐old man presenting with acute renal failure due to infiltration by T lymphoblasts and his response to paediatric
Externí odkaz:
https://doaj.org/article/fb2a4533e9ab4efba1a634ed819ed01c