Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Lymor Ringer"'
Autor:
Diane N. Ignacio, Kimberly D. Mason, Ezra C. Hackett-Morton, Christopher Albanese, Lymor Ringer, William D. Wagner, Paul C. Wang, Michael A. Carducci, Sushant K. Kachhap, Channing J. Paller, Janet Mendonca, Leo Li-Ying Chan, Bo Lin, Diane K. Hartle, Jeffrey E. Green, Collis A. Brown, Tamaro S. Hudson
Publikováno v:
Heliyon, Vol 5, Iss 1, Pp e01128- (2019)
Previously we demonstrated that muscadine grape skin extract (MSKE), a natural product, significantly inhibited androgen-responsive prostate cancer cell growth by inducing apoptosis through the targeting of survival pathways. However, the therapeutic
Externí odkaz:
https://doaj.org/article/0ec72566e263420685711b900634964a
Autor:
Paul Sirajuddin, Muhammad Umer Choudhry, Erika Parasido, Angiela Sivakumar, Lymor Ringer, Venkata Mahidhar Yenugonda, Iman Abdelgawad, Maria Laura Avantaggiati, Olga Rodriguez, Bhaskar Kallakury, Richard T. Lee, Adam S. Feldman, Chris Albanese, John H. Lynch, Sarah Waye, Mary M. Heckler, Anatoly Dritschilo, Richard G. Pestell, Aisha Naeem, Xuefeng Liu, Lucas Tricoli, Richard Schlegel, Chin-Lee Wu
Publikováno v:
Oncotarget
// Lymor Ringer 1,* , Paul Sirajuddin 1,* , Lucas Tricoli 1,* , Sarah Waye 1 , Muhammad Umer Choudhry 1 , Erika Parasido 1 , Angiela Sivakumar 1 , Mary Heckler 1 , Aisha Naeem 1 , Iman Abdelgawad 1,6 , Xuefeng Liu 2 , Adam S. Feldman 3 , Richard J. L
Autor:
Stanley T. Fricke, Emanuel F. Petricoin, Michael P. Lisanti, Yichien Lee, Angiela Sivakumar, Patricia Salinas, Aykut Üren, Richard Schlegel, Sana D. Karam, Sudeep Das, Sean S. Wang, Paul Sirajuddin, Bahram Moasser, Alpay Ozcan, Chris Albanese, Brian R. Rood, Venkata Mahidhar Yenugonda, Olga Rodriguez, Lymor Ringer, Yue Wang, Michael J. Pishvaian
Publikováno v:
Cell Cycle
The development of new small molecule-based therapeutic drugs requires accurate quantification of drug bioavailability, biological activity and treatment efficacy. Rapidly measuring these endpoints is often hampered by the lack of efficient assay pla
Autor:
Richard T. Lee, Hinanit Koltai, Christopher Albanese, Claire B. Pollock, Richard Schlegel, Ronit I. Yarden, Lymor Ringer, Hyo-Jung Lee, Victor S. Wang, Xin Li, Cristina Prandi, Yoram Kapulnik, Sara McDonough, Olga Rodriguez, Adam S. Feldman
Publikováno v:
Oncotarget
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
Strigolactones are a novel class of plant hormones produced in roots and regulate shoot and root development. We have previously shown that synthetic strigolactone analogues potently inhibit growth of breast cancer cells and breast cancer stem cells.
Autor:
Lymor Ringer
Cyclin-dependent kinase inhibitor VMY-1-103 induces a G2/M cell cycle arrest and apoptosis in prostate cancer cell lines. Cancer cell lines, including prostate cancer, show a differential sensitivity to VMY-1-103 that correlates with p53 status. In a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b42f4ffaae4fa76583746c6b376bf8
https://doi.org/10.21236/ada592440
https://doi.org/10.21236/ada592440
Autor:
Lymor Ringer, Chris Albanese, Jeffrey A. Toretsky, Aykut Üren, Olga Rodriguez, Milton L. Brown, Tobey J. MacDonald, Frank A. Suprynowicz, Anup K. Ghosh, Yichien Lee, Mary M. Heckler, Paul Sirajuddin, Venkata Mahidhar Yenugonda, Robert I. Glazer, Richard Schlegel
Medulloblastoma is the most prevalent of childhood brain malignancies, constituting 25% of childhood brain tumors. Craniospinal radiotherapy is a standard of care, followed by a 12mo regimen of multi-agent chemotherapy. For children less than 3 y of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a7305b20b8b2d800ee8ca5a19ddfc2
https://europepmc.org/articles/PMC3367670/
https://europepmc.org/articles/PMC3367670/
Autor:
Jeffrey A. Toretsky, Kamal P. Sajwan, Lymor Ringer, Metin Ozdemirli, Olga Rodriguez, Tobey J. MacDonald, Gülay Bulut, Michael D. Hall, Daniel Peaceman, Chris Albanese, Aykut Üren, Elspeth M. Beauchamp, Yichien Lee
The Hedgehog (Hh) pathway is activated in some human cancers, including medulloblastoma. The glioma-associated oncogene homolog (GLI) transcription factors are critical mediators of the activated Hh pathway, and their expression may be elevated in so
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::744f3a35b05ca7f0b3b26f1c2a7ac904
https://europepmc.org/articles/PMC3007144/
https://europepmc.org/articles/PMC3007144/
Autor:
Yesha Patel, Chris Albanese, Maria Laura Avantaggiati, Dean S. Rosenthal, Milton L. Brown, Paul Sirajuddin, Lymor Ringer, Amanda Brophy, Venkata Mahidhar Yenugonda, Valerie A. Trabosh, Anup K. Ghosh, Kyle A. DiVito, Scott Grindrod, Olga Rodriguez, Michael P. Lisanti
Publikováno v:
Cancer biologytherapy. 10(4)
The 2,6,9-trisubstituted purine group of cyclin dependent kinase inhibitors have the potential to be clinically relevant inhibitors of cancer cell proliferation. We have recently designed and synthesized a novel dansylated analog of purvalanol B, ter
Autor:
Sarada Vissapragada, Anup Ghosh, Lymor Ringer, Paul Sirajuddin, Patricia Salinas, Amanda Brophy, Daniel Peaceman, Bhaskar Kallakury, Partha P. Banerjee, Stanley T. Fricke, William Helfrich, Yi Chien Lee, Richard Pestell, Philipp Scherer, Herbert B. Tanowitz, Maria Laura Avantaggiati, Leena Hilakivi-Clarke, Michael P. Lisanti, Olga C. Rodriguez, Chris Albanese
Publikováno v:
Cell cycle (Georgetown, Tex.). 9(9)
Diet and obesity, and their associated metabolic alterations, are some of the fastest-growing causes of disease and death in America. Findings from epidemiological studies correlating obesity, the sources of dietary fat and prostate cancer (PCa) are
Autor:
Paul Sirajuddin, Bahram Moasser, Christopher Albanese, Sudeep Das, Patricia Salinas, Milton L. Brown, Olga Rodriguez, Lymor Ringer, Venkata Mahidhar Yenugonda
Publikováno v:
Cancer Research. 72:4774-4774
The development of new small molecule kinase inhibitors as cancer therapeutic drugs has placed increased emphasis on determining the mechanism of action of the new compounds preclinically, such as in genetically engineered mice or using human tissue