Zobrazeno 1 - 10
of 255
pro vyhledávání: '"Lyle Isaacs"'
Publikováno v:
Molecular Imaging, Vol 17 (2018)
Positron emission tomography (PET) imaging with biological macromolecules greatly expands the possibilities of molecular imaging. There are, however, practical aspects limiting the potential of the approach, including the dosimetric consequences of t
Externí odkaz:
https://doaj.org/article/fc022d4070b04dc2bd6dafbad4f4f024
Publikováno v:
Acta Crystallographica Section E, Vol 70, Iss 4, Pp o446-o446 (2014)
In the title compound, C8H9NO4, the pyrrolidine ring (r.m.s. deviation 0.014 Å) is almost normal to the mean plane of the propenoate group (r.m.s deviation 0.028 Å), making a dihedral angle of 86.58 (4)°. In the crystal, molecules are linked via p
Externí odkaz:
https://doaj.org/article/eb5c2c60d46a44bca41206556cc3332d
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10514 (2010)
BackgroundMany drug delivery systems are based on the ability of certain macrocyclic compounds - such as cyclodextrins (CDs) - to act as molecular containers for pharmaceutical agents in water. Indeed beta-CD and its derivatives have been widely used
Externí odkaz:
https://doaj.org/article/cfe60645f0a54720809dfea2241a8141
Publikováno v:
Acta Crystallographica Section E, Vol 64, Iss 7, Pp o1321-o1322 (2008)
The title inclusion complex, C36H36N24O12·C8H14N22+·2I−·10H2O, displays a large ellipsoidal deformation of the cucurbit[6]uril (CB[6]) skeleton upon complex formation. The benzene ring of the cation is rotationally disordered between two orienta
Externí odkaz:
https://doaj.org/article/4106f69bbb584e07ba47398ac8c59742
Autor:
David King, Tatjana Šumanovac, Steven Murkli, Peter R. Schreiner, Marina Šekutor, Lyle Isaacs
Publikováno v:
New Journal of Chemistry. 47:5338-5346
Cationic triamantanes exhibit ultratight binding toward CB[7] and CB[8] as evidenced by 1H NMR spectroscopy, isothermal titration calorimetry, and computations.
Autor:
Yue Wang, Rong-Zu Liang, Tian-Zhi Jia, Xue-Li Cao, Qian Wang, Jing-Rong Cao, Shuo Li, Qixun Shi, Lyle Isaacs, Shi-Peng Sun
Publikováno v:
Journal of the American Chemical Society. 144:6483-6492
Autor:
David King, Chelsea R. Wilson, Lukas Herron, Chun-Lin Deng, Shams Mehdi, Pratyush Tiwary, Fraser Hof, Lyle Isaacs
Publikováno v:
Organic & Biomolecular Chemistry. 20:7429-7438
The molecular recognition properties of Pillar[6]MaxQ toward methylated amino acids, amino acid amides, and peptides is investigated by a combination of 1H NMR, ITC, indicator displacements assays, and molecular dynamics simulations.
Autor:
Dilanka V. D. Walpita Kankanamalage, Jennifer H. T. Tran, Noah Beltrami, Kun Meng, Xiao Zhou, Pravin Pathak, Lyle Isaacs, Alexander L. Burin, Mehnaaz F. Ali, Janarthanan Jayawickramarajah
Publikováno v:
Journal of the American Chemical Society. 144(36)
Base-pair-driven toehold-mediated strand displacement (BP-TMSD) is a fundamental concept employed for constructing DNA machines and networks with a gamut of applications─from theranostics to computational devices. To broaden the toolbox of dynamic
Autor:
Canjia Zhai, Lyle Isaacs
Publikováno v:
Chemistry – A European Journal. 28
We report that the direct macrocyclization of naphthalene monomers bearing ethyl ester functional groups delivers prism[5]arene derivatives, which can be deprotected to yield water-soluble prism[5]arenes (H1 and H3).
Publikováno v:
Angewandte Chemie International Edition. 61
Benzene, toluene and pyridine are widely used as essential raw materials in industry and laboratory research, with stringent purity requirements. Herein, we show that solid double-cavity host nor-seco-cucurbit[10]uril (ns-Q[10]) functions as an effic