Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Lyle F. Mockros"'
Publikováno v:
ASAIO Journal. 54:390-395
Lithographic techniques were used to develop patterned silicone rubber membranes that provide 15 microm high microchannels for artificial lungs. Two types of devices were fabricated as a proof-of-concept: one has a series of parallel, straight, open
Autor:
J Constantine Mavroudis, J Carl L Backer, Carrie E. Perlman, J Ralf Seipelt, Keith E. Cook, Lyle F. Mockros
Publikováno v:
ASAIO Journal. 51:412-425
A thoracic artificial lung (TAL) was attached to the pulmonary circulation in a porcine model. Proximal main pulmonary artery (PA) blood flow, in part or whole, was diverted to the TAL, and TAL outlet blood flow was split between the distal main PA a
Autor:
Keith E. Cook, Carl L. Backer, Carrie E. Perlman, Ralf G. Seipelt, Lyle F. Mockros, Constantine Mavroudis
Publikováno v:
ASAIO Journal. 51:404-411
A compliant thoracic artificial lung (TAL) has been developed for acute respiratory failure or as a bridge to transplantation. The development goal was to increase TAL compliance, lower TAL impedance, and improve right ventricular function during use
Autor:
David J. Leonard, Constantine Mavroudis, Carl L. Backer, Lyle F. Mockros, Keith E. Cook, Justin Maxhimer
Publikováno v:
ASAIO Journal. 48:620-630
Blood contact with the prosthetic surfaces of artificial lungs causes extensive activation of molecular and cellular mediators of coagulation and inflammation that can lead to patient morbidity and mortality. To determine the effects of artificial lu
Publikováno v:
ASAIO Journal. 46:42-48
A thoracic artificial lung (TAL) was designed to treat respiratory insufficiency, acting as a temporary assist device in acute cases or as a bridge to transplant in chronic cases. We developed a computational model of the pulmonary circulatory system
Publikováno v:
Journal of Biomechanics. 32:1165-1175
Leukocytes interact with endothelial cells and contribute to the development of vascular diseases such as thrombosis and atherosclerosis. These processes are possibly influenced by mechanical factors. This study focused on the role of mechanical stre
Autor:
Michael J. Vonesh, Krishnan B. Chandran, Charles J. Davidson, David D. McPherson, Lyle F. Mockros
Publikováno v:
Annals of Biomedical Engineering. 25:882-895
Stress-induced structural damage is often accompanied by sound release. This behavior is known as acoustic emission (AE). We hypothesize that vascular injury such as that produced by balloon angioplasty is associated with AE. Postmortem human periphe
Autor:
Ronald J. Leonard, H. J. Przybylo, Susan E. Crawford, José M. de la Torre Hernández, Anthony J. Makarewicz, Carl L. Backer, Lyle F. Mockros, Keith E. Cook, Constantine Mavroudis
Publikováno v:
ASAIO JOURNAL. 42:M604-608
A low input impedance, intrathoracic artificial lung is being developed for use in acute respiratory failure or as a bridge to transplantation. The device uses microporous, hollow fibers in a 0.74 void fraction, 1.83 m2 surface area bundle. The bundl
Publikováno v:
ASAIO JOURNAL. 42:M615-619
A new prototype of a pumping artificial lung (PAL) has been designed and tested. The device performs the functions of both the pump and oxygenator components of an extracorporeal perfusion circuit. Previous prototypes that the authors developed (Type
Autor:
Carrie E. Perlman, Lyle F. Mockros
Publikováno v:
ASAIO journal (American Society for Artificial Internal Organs : 1992). 58(3)
A thoracic artificial lung (TAL) provides respiratory support for lung disease. How well a TAL improves blood oxygenation for a specific pathology depends on how the TAL is attached to the pulmonary circulation: in series with the natural lungs (NLs)