Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Lyle Burton"'
Publikováno v:
Journal of Proteome Research. 21:2462-2471
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43a4bc3ddcb4ff18f788d54dc88bc2f9
https://doi.org/10.1021/acs.jproteome.2c00378
https://doi.org/10.1021/acs.jproteome.2c00378
Publikováno v:
Journal of proteome research. 21(10)
We describe a method to obtain a comprehensive profile of multiple glycosylations in glycopeptide isoforms. We detected a wide range of abundances of various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::331ee079202e0e0630966263c1c4d462
https://pubmed.ncbi.nlm.nih.gov/36074808
https://pubmed.ncbi.nlm.nih.gov/36074808
Autor:
Ron Bonner, Eva Duchoslav, Gérard Hopfgartner, Emmanuel Varesio, Anita Orsolya Hidasi, Tobias Bruderer, Lyle Burton
Publikováno v:
Analytical and Bioanalytical Chemistry, Vol. 410, No 7 (2018) pp. 1873-1884
High-quality mass spectral libraries have become crucial in mass spectrometry-based metabolomics. Here, we investigate a workflow to generate accurate mass discrete and composite spectral libraries for metabolite identification and for SWATH mass spe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710f29decad4836ed896cb9d901e51da
https://doi.org/10.1007/s00216-018-0860-x
https://doi.org/10.1007/s00216-018-0860-x
Publikováno v:
Clinical Mass Spectrometry. 3:7-12
A common method for identifying an unknown compound involves acquiring its mass spectrum and then comparing that spectrum against a spectral database, or library. Accurate comparison and identification is dependent on the quality of both the library
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e129b919c79e29bad32eda395eda133f
https://doi.org/10.1016/j.clinms.2017.04.001
https://doi.org/10.1016/j.clinms.2017.04.001
Publikováno v:
Bioanalysis. 8:1679-1691
Aim: The commonly used LC–MS workflow to quantify protein therapeutics in biological samples is ‘bottom-up’ approach. In this study, the aim is to establish ‘top-down’ approach for absolute quantitation of therapeutic antibodies or proteins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::964c65cd0f6e1e02568ac755b81ed721
https://doi.org/10.4155/bio-2016-0096
https://doi.org/10.4155/bio-2016-0096
Publikováno v:
Bioanalysis. 10(11)
Aim: Compared with small molecules, LC–MS quantitation of larger biotherapeutic proteins such as antibodies and antibody–drug conjugates at the intact level presents many challenges in both LC and MS due to their higher molecular weight, bigger s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee73aaee2b7cb9bede422d11e7cc5c80
https://pubmed.ncbi.nlm.nih.gov/29863890
https://pubmed.ncbi.nlm.nih.gov/29863890
SWATH-ID: An instrument method which combines identification and quantification in a single analysis
Publikováno v:
Proteomics. 17(10)
Data-independent acquisition (DIA) approaches, such as SWATH® -MS, are showing great potential to reliably quantify significant numbers of peptides and proteins in an unbiased manner. These developments have enhanced interest in developing a single
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0251dc9bed65adc9c159600c73d62de
https://pubmed.ncbi.nlm.nih.gov/28387034
https://pubmed.ncbi.nlm.nih.gov/28387034
Publikováno v:
Analytical Chemistry. 80:4933-4944
Many modern applications of analytical chemistry involve the collection of large megavariate data sets and subsequent processing with multivariate analysis techniques (MVA), two of the more common goals being data analysis (also known as data mining
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c86a09e253304230d1c36f434cd9a692
https://doi.org/10.1021/ac800110w
https://doi.org/10.1021/ac800110w
Publikováno v:
Analytical Chemistry. 78:1296-1305
In the field of metabonomics, 1H NMR and full scan mass spectrometry methods have usually been combined with principal component analysis (PCA) and partial least squares discriminant analysis (PLS-DA) to detect patterns in biofluids that correspond t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c90c8f2d1b70f4dcf7a3077d8ee9a7e7
https://doi.org/10.1021/ac051705s
https://doi.org/10.1021/ac051705s
Autor:
Gérard Hopfgartner, Emmanuel Varesio, Ron Bonner, Lyle Burton, Rayane Mohamed, Gordana Ivosev
Publikováno v:
Analytical Chemistry, Vol. 81, No 18 (2009) pp. 7677-94
A comprehensive analytical LC-MS(/MS) platform for low weight biomarkers molecule in biological fluids is described. Two complementary retention mechanisms were used in HPLC by optimizing the chromatographic conditions for a reversed-phase column and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c3e0ff31881da6a44c3d28dd1adf3fe
https://pubmed.ncbi.nlm.nih.gov/19702294
https://pubmed.ncbi.nlm.nih.gov/19702294