Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Lyle B. Zimmerman"'
Autor:
Laia Ribas, Ming-Shi Li, Benjamin J Doddington, Jacques Robert, Judith A Seidel, J Simon Kroll, Lyle B Zimmerman, Nicholas C Grassly, Trenton W J Garner, Matthew C Fisher
Publikováno v:
PLoS ONE, Vol 4, Iss 12, p e8408 (2009)
Amphibians are experiencing a panzootic of unprecedented proportions caused by the emergence of Batrachochytrium dendrobatidis (Bd). However, all species are not equally at risk of infection, and risk is further modified by environmental variables, s
Externí odkaz:
https://doaj.org/article/ed934a09e94246b99af3cd27f8421c85
Autor:
Tadahiro Goda, Anita Abu-Daya, Samantha Carruthers, Matthew D Clark, Derek L Stemple, Lyle B Zimmerman
Publikováno v:
PLoS Genetics, Vol 2, Iss 6, p e91 (2006)
We present here the results of forward and reverse genetic screens for chemically-induced mutations in Xenopus tropicalis. In our forward genetic screen, we have uncovered 77 candidate phenotypes in diverse organogenesis and differentiation processes
Externí odkaz:
https://doaj.org/article/9ef4d825de834e0db38a7eb1bdf0b86d
Publikováno v:
Genesis (New York, N.y. : 2000)
Summary Sarcomere structure underpins structural integrity, signaling, and force transmission in the muscle. In embryos of the frog Xenopus tropicalis, muscle contraction begins even while sarcomerogenesis is ongoing. To determine whether contractile
Autor:
Caroline S. Hill, Eric A. Miska, Joanne L. Harding, Claire Heliot, Stuart Horswell, Javier Armisen, Lyle B. Zimmerman, Nicholas M. Luscombe
Publikováno v:
Genome Research; Vol 24
Small RNA control of gene expression is critical for developmental processes in vertebrate embryos. To determine the dynamics of small RNA expression and to uncover novel small RNAs in the early vertebrate embryo, we performed high-throughput sequenc
Autor:
Lyle B. Zimmerman, Michael J. Gilchrist, Abdul K. Sesay, Frédéric J. J. Chain, Eva Seifertova, Halina Cernohorska, Vladimir Krylov, Jaroslav Macha, Svatava Kubickova, Adam J. Bewick, Ben J. Evans, Vojtech Zarsky, Tereza Tlapakova, Nick D.L. Owens
Publikováno v:
Genome Biology and Evolution
Genome biology and evolution
Genome biology and evolution
Sex chromosome divergence has been documented across phylogenetically diverse species, with amphibians typically having cytologically nondiverged ("homomorphic") sex chromosomes. With an aim of further characterizing sex chromosome divergence of an a
Publikováno v:
genesis. 50:164-175
A decade after the human genome sequence, most vertebrate gene functions remain poorly understood, limiting benefits to human health from rapidly advancing genomic technologies. Systematic in vivo functional analysis is ideally suited to the experime
Autor:
Sigmund J. Degitz, Álvaro S Roco, Tosikazu Amano, Lyle B. Zimmerman, Mónica Bullejos, Allen W. Olmstead
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 112(34)
Homomorphic sex chromosomes and rapid turnover of sex-determining genes can complicate establishing the sex chromosome system operating in a given species. This difficulty exists in Xenopus tropicalis, an anuran quickly becoming a relevant model for
Autor:
Renee Aloise, Robert M. Grainger, Lyle B. Zimmerman, Selina Noramly, Marilyn Fisher, Amanda Cox
Publikováno v:
Mechanisms of Development. 122(3):273-287
In the rapidly developing, diploid amphibian Xenopus tropicalis, genetics can be married to the already powerful tools of the amphibian system to overcome a disability that has hampered Xenopus laevis as a model organism: the difficulties inherent in
Autor:
Richard M. Harland, Chen-Ming Fan, Jill A. McMahon, Shinji Takada, Andrew P. McMahon, Lyle B. Zimmerman
Publikováno v:
Genes & Development. 12:1438-1452
Embryonic patterning in vertebrates is dependent upon the balance of inductive signals and their specific antagonists. We show thatNoggin, which encodes a bone morphogenetic protein (BMP) antagonist expressed in the node, notochord, and dorsal somite
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 917
Xenopus tropicalis combine the advantages of X. laevis, for example using explants and targeted gain of function, with the ability to take classical genetics approaches to answering cell and developmental biology questions making it arguably the most