Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lydie Viatte"'
Autor:
Manfred Nairz, Thomas Sonnweber, Bruno Galy, Ferric C. Fang, Daniela Casarrubea, Dunja Ferring-Appel, Andrea Schroll, David Haschka, Matthias W. Hentze, Lydie Viatte, Guenter Weiss
Publikováno v:
Cell Host & Microbe. 18(2):254-261
SummaryMacrophages are essential for systemic iron recycling, and also control iron availability to pathogens. Iron metabolism in mammalian cells is orchestrated posttranscriptionally by iron-regulatory proteins (IRP)-1 and -2. Here, we generated mic
Autor:
Jacques Mathieu, Lydie Viatte, Sophie Vaulont, Sara Zumerle, Stéphanie Delga, Carole Peyssonnaux
Publikováno v:
American Journal of Hematology
Autor:
T. Hallas, Klaus Schümann, Richard S. Eisenstein, Matthias W. Hentze, Daniela Casarrubea, A. Vasanthakumar, Bruno Galy, Lydie Viatte
Publikováno v:
Journal of Molecular Medicine (Berlin, Germany)
Disorders of iron metabolism account for some of the most common human diseases. Cellular iron homeostasis is maintained by iron regulatory proteins (IRP)-1 and 2 through their binding to cis-regulatory iron-responsive elements (IREs) in target mRNAs
Autor:
Sophie Vaulont, Lydie Viatte
Publikováno v:
Biochimie. 91:1223-1228
Hepcidin, a peptide hormone produced by the liver, constitutes the master regulator of iron homeostasis in mammals allowing iron adaptation according to the body iron needs. In recent years there has been important breakthrough in our knowledge of he
Publikováno v:
Journal of Molecular Medicine. 87:913-921
The maintenance of iron homeostasis is critical as both iron deficiency and iron excess are deleterious. In mammals, iron homeostasis is regulated systemically by the iron-hormone hepcidin, an acute-phase protein secreted by the liver which inhibits
Autor:
Sophie Vaulont, Axel Kahn, Lydie Viatte, Guillemette Ramey, Jeanne-Claire Lesbordes-Brion, Myriam Bennoun, Ghislaine Hamard, Dan-Qing Lou, Christophe Houbron
Publikováno v:
Blood. 108:1402-1405
We previously reported that mice made deficient for the transcriptional factor USF2 fail to express hepcidin 1 and hepcidin 2 genes as a consequence of targeted disruption of the Usf2 gene lying just upstream in the locus. These mice developed an iro
Autor:
Gaël Nicolas, Lydie Viatte, Gisèle Grimber, Marie-France Szajnert, Axel Kahn, Jeanne-Claire Lesbordes, Dan-Qing Lou, Sophie Vaulont
Publikováno v:
Blood. 103:2816-2821
Hepcidin is a 25-amino acid peptide involved in iron homeostasis in mice and humans. It is produced in the liver from a larger precursor, and it is detectable in blood and urine. In contrast to the human genome, which contains only one copy of the ge
Autor:
Lydie Viatte, Carole Peyssonnaux, Mylène Heinis, Sophie Vaulont, Jacques Mathieu, Stéphanie Delga, Sara Zumerle
Publikováno v:
Blood
Hepcidin is a 25-amino-acid peptide demonstrated to be the iron regulatory hormone capable of blocking iron absorption from the duodenum and iron release from macrophages. Mutations affecting hepcidin regulators or the hepcidin gene itself cause hemo
Autor:
Lydie Viatte
Publikováno v:
médecine/sciences. 25:557-559
557 NO UV EL LE S M AG AZ IN E a l’ADN par la NER est completement abolie durant la phase S. D’autre part, ATR ne joue aucun role dans la reparation de l’ADN pendant les phases G0/G1 ou G2/M [8]. Cette observation revele une nouvelle fonction c
Autor:
Sophie Vaulont, Lydie Viatte
Publikováno v:
médecine/sciences. 22:466-468
qu’a l’etat adulte est tres faible. Les rares survivants sont pâles, presentent un retard de croissance et une forte cardiomegalie, signes classiques d’insuffisance cardiaque. Le gene responsable de l’anomalie phenotypique du mutant frs code