Zobrazeno 1 - 10
of 91
pro vyhledávání: '"Lydia Wachsmuth"'
Autor:
Marit ten Hove, Andreas Smyris, Richell Booijink, Lydia Wachsmuth, Uwe Hansen, Lejla Alic, Cornelius Faber, Carsten Hӧltke, Ruchi Bansal
Publikováno v:
Bioactive Materials, Vol 39, Iss , Pp 406-426 (2024)
Endothelin-1/endothelin A receptor (ET-1/ETAR) pathway plays an important role in the progression of liver fibrosis by activating hepatic stellate cells (HSCs) - a key cell type involved in the pathogenesis of liver fibrosis. Inactivating HSCs by blo
Externí odkaz:
https://doaj.org/article/116128a5ac164a989510fd0e761073b3
Autor:
Lydia Wachsmuth, Leo Hebbelmann, Jutta Prade, Laura C. Kohnert, Henriette Lambers, Annika Lüttjohann, Thomas Budde, Andreas Hess, Cornelius Faber
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
IntroductionGenetic Absence Epilepsy Rats from Strasbourg (GAERS) represent a model of genetic generalized epilepsy. The present longitudinal study in GAERS and age-matched non-epileptic controls (NEC) aimed to characterize the epileptic brain networ
Externí odkaz:
https://doaj.org/article/c5decd9743e14e2bace3bb18abbc9874
Autor:
Martin Segeroth, Lydia Wachsmuth, Mathias Gagel, Franziska Albers, Andreas Hess, Cornelius Faber
Publikováno v:
Fluids and Barriers of the CNS, Vol 20, Iss 1, Pp 1-21 (2023)
Abstract Background Despite recent attention, pathways and mechanisms of fluid transposition in the brain are still a matter of intense discussion and driving forces underlying waste clearance in the brain remain elusive. Consensus exists that net so
Externí odkaz:
https://doaj.org/article/22061e76f3d947db8345694ec04c96aa
Autor:
Emily Hoffmann, Mirjam Gerwing, Tobias Krähling, Uwe Hansen, Katharina Kronenberg, Max Masthoff, Christiane Geyer, Carsten Höltke, Lydia Wachsmuth, Regina Schinner, Verena Hoerr, Walter Heindel, Uwe Karst, Michel Eisenblätter, Bastian Maus, Anne Helfen, Cornelius Faber, Moritz Wildgruber
Publikováno v:
Breast Cancer Research, Vol 25, Iss 1, Pp 1-16 (2023)
Abstract Background Response assessment of targeted cancer therapies is becoming increasingly challenging, as it is not adequately assessable with conventional morphological and volumetric analyses of tumor lesions. The tumor microenvironment is part
Externí odkaz:
https://doaj.org/article/bb457be90422403fb4b3cade4f355994
Autor:
Thomas Vogl, Moritz Wildgruber, Cornelius Faber, Emily Hoffmann, Mirjam Gerwing, Stephan Niland, Rolf Niehoff, Max Masthoff, Christiane Geyer, Lydia Wachsmuth, Enrica Wilken, Carsten Höltke, Walter L Heindel, Verena Hoerr, Regina Schinner, Philipp Berger, Johannes A Eble, Bastian Maus, Anne Helfen
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 3 (2023)
Background The inflammatory tumor microenvironment (TME) is formed by various immune cells, being closely associated with tumorigenesis. Especially, the interaction between tumor-infiltrating T-cells and macrophages has a crucial impact on tumor prog
Externí odkaz:
https://doaj.org/article/e0037d62af4746e08616a8d85ec2720a
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionSmall animal fMRI is an essential part of translational research in the cognitive neurosciences. Due to small dimensions and animal physiology preclinical fMRI is prone to artifacts that may lead to misinterpretation of the data. To reach
Externí odkaz:
https://doaj.org/article/14404a21c66e477d8624e5856aa5456e
Autor:
Mirjam Gerwing, Emily Hoffmann, Katharina Kronenberg, Uwe Hansen, Max Masthoff, Anne Helfen, Christiane Geyer, Lydia Wachsmuth, Carsten Höltke, Bastian Maus, Verena Hoerr, Tobias Krähling, Lena Hiddeßen, Walter Heindel, Uwe Karst, Melanie A. Kimm, Regina Schinner, Michel Eisenblätter, Cornelius Faber, Moritz Wildgruber
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ObjectiveThe objective of this study was to non-invasively differentiate the degree of malignancy in two murine breast cancer models based on identification of distinct tissue characteristics in a metastatic and non-metastatic tumor model using a mul
Externí odkaz:
https://doaj.org/article/107f5fb2d2b74102a992a5af89cfb498
Autor:
Manuela Cerina, Muthuraman Muthuraman, Marco Gallus, Nabin Koirala, Andre Dik, Lydia Wachsmuth, Petra Hundehege, Patrick Schiffler, Jan-Gerd Tenberge, Vinzenz Fleischer, Gabriel Gonzalez-Escamilla, Venu Narayanan, Julia Krämer, Cornelius Faber, Thomas Budde, Sergiu Groppa, Sven G. Meuth
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-16 (2020)
Abstract Background Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS), characterized by inflammatory and neurodegenerative processes. Despite demyelination being a hallmark of the disease, how it relates to neurodeg
Externí odkaz:
https://doaj.org/article/04861f764dbb4359978bce487ff0e7bf
Autor:
Bruno Pradier, Lydia Wachsmuth, Nina Nagelmann, Daniel Segelcke, Silke Kreitz, Andreas Hess, Esther M. Pogatzki-Zahn, Cornelius Faber
Publikováno v:
NeuroImage, Vol 245, Iss , Pp 118626- (2021)
For fMRI in animal models, the combination of low-dose anesthetic, isoflurane (ISO), and the sedative medetomidine (MED) has recently become an advocated regimen to achieve stable neuronal states and brain networks in rats that are required for relia
Externí odkaz:
https://doaj.org/article/4f043c323b3e4914aa3325c4b08d3592
Autor:
Max Masthoff, Felix Noah Freppon, Lisa Zondler, Enrica Wilken, Lydia Wachsmuth, Silke Niemann, Christian Schwarz, Ina Fredrich, Asli Havlas, Helena Block, Mirjam Gerwing, Anne Helfen, Walter Heindel, Alexander Zarbock, Moritz Wildgruber, Cornelius Faber
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103670- (2021)
Background: Immune cells show distinct motion patterns that change upon inflammatory stimuli. Monocytes patrol the vasculature to screen for pathogens, thereby exerting an early task of innate immunity. Here, we aimed to non-invasively analyse single
Externí odkaz:
https://doaj.org/article/04693da21a3d46ce8204d1a900639621